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Volumn 68, Issue 2, 2011, Pages 237-247
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Synthesis of new functionalized 3-subsitituted [1,2,4]triazolo [4,3-a]pyrimidine dreivatives: Potential antihypertensive agents
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Author keywords
1,3,4 oxadiazole; 1,3,4 thiadiazole; Antihypertensive; Dioxoisoindoline; Diuretic activities; Thiazole; Thiosemicarbazide; Triazolo 4,3 a pyrimidine
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Indexed keywords
1 (1,5 DIHYDRO 5 OXO 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 3 CARBONYL) PHENYLTHIOSEMICARBAZIDE;
1 (1,5 DIHYDRO 5 OXO 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDINE 3 CARBONYL) THIOSEMICARBAZIDE;
1,5 DIHYDRO 5 OXO 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDINE 3 CARBOHYDRAZIDE;
1,5 DIHYDRO 5 OXO 1,7 DIPHENYL N (3,4 DIPHENYL 3H THIAZOL YLIDENE 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 3 CARBOHYDRAZIDE;
1,5 DIHYDRO 5 OXO N (1,3 DIOXOISOINDOLIN 2 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 3 CARBOXAMIDE;
1,7 DIPHENYL 3 (5 AMINO 1,3,4 THIADIAZOL 2 YL) 1,2,4 TRIAZOLO[4,3 A]PYRIMIDINE 5 (1H) ONE;
1,7 DIPHENYL 3 (5 PHENYLAMINO 1,3,4 THIADIAZOL 2 YL) 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 5 (1H) ONE;
3 (3 METHYLPYRAZOLE 5 OXO 1 CARBONYL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3A]PYRIMIDIN 5 (1H) ONE;
3 (3,5 DIMETHYLPYRAZOLE 1 CARBONYL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3A]PYRIMIDIN 5 (1H) ONE;
3 (5 AMINO 1,3,4 OXADIAZOL 2 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 5 (1H) ONE;
3 (5 HYDRAZINO 4 PHENYL 4H 1,2,4 TRIAZOL 3 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 5 (1H) ONE;
3 (5 MERCAPTO 1,3,4 OXADIAZOL 2 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 5 (1H) ONE;
3 (5 MERCAPTO 4 AMINO 4H [1,2,4] TRIAZOL 3 YL) 1,7 DIPHENYL[1,2,4]TRIAZOLO[4,3A]PYRIMIDIN 5(1H) ONE;
3 (5 MERCAPTO 4 PHENYL 4H 1,2,4 TRIAZOL 3 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3A]PYRIMIDIN 5 (1H) ONE;
3 (5 MERCAPTO 4H 1,2,4 TRIAZOL 3 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDINE 5(1H) ONE;
3 (5 METHYLTHIO 4 PHENYL 4H 1,2,4 TRIAZOL 3 YL) 1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3 A]PYRIMIDIN 5 (1H) ONE;
ANTIHYPERTENSIVE AGENT;
CAPTOPRIL;
FUROSEMIDE;
N (4,5,6,7 TETRACHLORO 1,3 DIOXOISOINDOLIN 2 YL) 1,5 DIHYDRO 5 OXO (1,7 DIPHENYL 1,2,4 TRIAZOLO[4,3A]PYRIMIDIN 3 CARBOXAMIDE;
PYRAZOLE;
PYRIMIDINE DERIVATIVE;
REAGENT;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANTIHYPERTENSIVE ACTIVITY;
ARTICLE;
DIURETIC ACTIVITY;
DRUG SYNTHESIS;
LD 50;
MALE;
NONHUMAN;
RAT;
SUBSTITUTION REACTION;
ANIMALS;
ANTIHYPERTENSIVE AGENTS;
BLOOD PRESSURE;
DISEASE MODELS, ANIMAL;
DIURESIS;
DIURETICS;
GAS CHROMATOGRAPHY-MASS SPECTROMETRY;
HYPERTENSION;
LETHAL DOSE 50;
MAGNETIC RESONANCE SPECTROSCOPY;
MALE;
MICE;
MOLECULAR STRUCTURE;
PYRIMIDINES;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
RATS;
RATS, INBRED SHR;
SPECTROSCOPY, FOURIER TRANSFORM INFRARED;
TRIAZOLES;
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EID: 79953245462
PISSN: 00016837
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
Times cited : (41)
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References (25)
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