Tumor Delivery of ultrasound contrast agents using shiga toxin B subunit

Molecular Imaging

Volumn 10, Issue 2, 2011, Pages 135-143

  Couture, Olivier ^a,b,c,d   Dransart, Estelle ^a,b,c,d   Dehay, Sabrina ^a,b,c,d   Nemati, Fariba ^a,b,c,d   Decaudin, Didier ^a,b,c,d   Johannes, Ludger ^a,b,c,d   Tanter, Mickael ^a,b,c,d  

^a INSTITUT LANGEVIN   (France)

^b INSTITUT CURIE   (France)

^c INSTITUT CURIE   (France)

^d Fondation Pierre Gilles de Gennes Pour la Recherche   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; BACK-SCATTERED; CELL-BINDING; CONTRAST ENHANCEMENT; CULTURE PLATES; FUNCTIONALIZED; GLYCO LIPIDS; IN-VITRO; MICRO-BUBBLE; MICROBUBBLES; NEOVASCULATURE; OVER-EXPRESSION; SHIGA TOXIN; SIGNAL INTENSITIES; SUBCUTANEOUS TUMOR; TUMOR CELLS; ULTRASOUND CONTRAST AGENT;

FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; LIGANDS; TOXIC MATERIALS; TUMORS; ULTRASONIC IMAGING; ULTRASONICS;

CELL CULTURE;

CERAMIDE TRIHEXOSIDE; CONTRAST MEDIUM; GLOBOTRIAOSYLCERAMIDE; PROTEIN SUBUNIT; SHIGA TOXIN;

ANIMAL; ARTICLE; CELL STRAIN HT29; DRUG DELIVERY SYSTEM; DRUG SCREENING; ECHOGRAPHY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; METHODOLOGY; MICROBUBBLE; MOUSE; NEOPLASM; NONLINEAR SYSTEM; PROTEIN BINDING;

ANIMALS; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; FLOW CYTOMETRY; HT29 CELLS; HUMANS; MICE; MICROBUBBLES; MICROSCOPY, FLUORESCENCE; NEOPLASMS; NONLINEAR DYNAMICS; PROTEIN BINDING; PROTEIN SUBUNITS; SHIGA TOXIN; TRIHEXOSYLCERAMIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79953236196     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2010.00030     Document Type: Article

References (41)

1. Qin S, Caskey CF, Ferrara KW. Ultrasound contrast microbubbles in imaging and therapy: Physical principles and engineering. Phys Med Biol 2009;54:R27-57.
2. Burns PN, Wilson SR. Microbubble contrast for radiological imaging: 1-principles. Ultrasound Q 2006;22:5-13. (Pubitemid 44510222)
3. Dijkmans PA, Knaapen P, Sieswerda GTJ, et al. Quantification of myocardial perfusion using intravenous myocardial contrast echocardiography in healthy volunteers: Comparison with position emission tomography. J Am Soc Echocardiogr 2006;19:285-93. (Pubitemid 43267452)
4. Wilson SR, Burns PN. Microbubble contrast for radiological imaging: 1-applications. Ultrasound Q 2006;22:15-8. (Pubitemid 44510223)
5. Fisher T, Dieckhofer J, Muhler M, et al. The use of contrastenhanced US in renal transplant. Eur Radiol 2005;15:E109-16.
6. Xiong L, Deng YB, Zhu Y, et al. Correlation of carotid plaque neovascularization detected by using contrast-enhanced US with clinical symptoms. Radiology 2009;251:583-9.
7. Dayton PA, Rychak JJ. Molecular ultrasound imaging using microbubble contrast agents. Front Biosci 2007;12:5124-42.
8. Willmann JK, Cheng Z, Davis C, et al. Targeted microbubbles for imaging tumor angiogenesis: Assessment of whole-body distribution with dynamic micro-PET in mice. Radiology 2008;249: 212-9.
9. Lindner JR, Coggins MP, Kaul S, et al. Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes. Circulation 2000;101:668-75. (Pubitemid 30094739)
10. Schumann PA, Christiansen JP, Quigley RM, et al. Targetedmicrobubble binding selectively to GPIIb IIIa receptors of platelet thrombi. Invest Radiol 2002;37:587-93. (Pubitemid 35231692)
11. Ferrara KW, Merritt CR, Burns PN, et al. Evaluation of tumor angiogenesis with US: Imaging, Doppler, and contrast agents. Acad Radiol 2000;7:824-39.
12. Chappell CJ, Price RJ. Targeted therapeutic applications of acoustically active microspheres in the microcirculation. Microcirculation 2006;13:57-70.
13. Lyshchik A, Fleischer AC, Huamani J, et al. Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography. J Ultrasound Med 2007;26:1575-86. (Pubitemid 351519803)
14. Ellegala DB, Leong-Poi H, Carpenter JE, et al. Imaging tumor angiogenesis with contrast ultrasound and microbubbles targeted to alpha(v)beta3. Circulation 2003;108:336-41. (Pubitemid 36899026)
15. Hakomori S. Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res 1996;56:5309-18. (Pubitemid 27011703)
16. Arab S, Russel E, Chapman WB, et al. Expression of the verotoxin receptor glycolipid, globotriaosylceramide, in ovarian hyperplasias. Oncol Res 1997;9:553-63. (Pubitemid 127761181)
17. Ohyama C, Fukushi Y, Satoh M, et al. Changes in glycolipid expression in human testicular tumor. Int J Cancer 1990;45: 1040-4. (Pubitemid 20201572)
18. LaCasse EC, Bray MR, et al. Shiga-like toxin-1 receptor on human breast cancer, lymphoma and myeloma. Blood 1999;94:2901-10.
19. Kovbasnjuk O, Mourtazina R, Baibakov B, et al. The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer. Proc Natl Acad Sci U S A 2006;102:19087-92.
20. Falguières T, Maak M, von Weyhern C, et al. Human colorectal tumors and metastases express Gb3 and can be targeted by an intestinal pathogen-based delivery tool. Mol Cancer Ther 2008;7: 2498-508.
21. Kalisiak A, Minniti JG, Oosterwijk E, et al. Neutral glycosphingolipid expression in B-cell neoplasms. Int J Cancer 1991; 49:837-45.
22. Hannah MH, Lingwood CA. Verotoxin sensitivity of ECV304 cells in vitro and in vivo in a xenograph tumour model: VT1 as a tumour neovascular marker. Angiogenesis 2003;6:129-41. (Pubitemid 38173864)
23. Lingwood CA. Verotoxin/globotriaosyl ceramide recognition: Angiopathy, angiogenesis and antineoplasia. Biosci Rep 1999;19: 345-54. (Pubitemid 30169335)
24. Johannes L, Römer W. Shiga toxins - from cell biology to biomedical applications. Nat Rev Microbiol 2010;8:105-16.
25. Johannes L, Popoff V. Tracing the retrograde route in protein trafficking. Cell 2008;135:1175-87.
26. Lord JM, Roberts LM, Lencer WI. Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: Co-opting basic mechanisms of endoplasmic reticulumassociated degradation. Curr Top Microbiol Immunol 2005;300: 149-68. (Pubitemid 43057940)
27. St Hilaire PM, Boyd MK, Toone EJ. Interaction of the Shiga-like toxin type-1 b-subunit with its carbohydrate receptor. Biochemistry 1994;33:14452-63.
28. Pina DG, Gomez J, Villar E, et al. Thermodynamic analysis of the structural stability of the Shiga toxin B-subunit. Biochemistry 2003;42:9498-506. (Pubitemid 36959258)
29. Johannes L, Decaudin D. Protein toxins: Intracellular trafficking for targeted therapy. Gene Ther 2005;16:1360-8. (Pubitemid 43090385)
30. Janssen KP, Vignjevic D, Boisgard R, et al. In vivo tumor targeting using a novel intestinal pathogen-based delivery approach. Cancer Res 2006;66:7230-6. (Pubitemid 44197703)
31. Viel T, Dransart E, Nemati F, et al. In vivo tumor targeting by the B-subunit of Shiga toxin. Mol Imaging 2008;7:239-47.
32. El Alaoui A, Schmidt F, Amessou M, et al. Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug. Angew Chem Int Ed Engl 2007;46:6469-72. (Pubitemid 47340174)
33. El Alaoui A, Schmidt F, Sarr M, et al. Synthesis and properties of a mitochondrial peripheral benzodiazepine receptor conjugate. Chem Med Chem 2008;3:1687-95.
34. Amessou M, Carez D, Patin P, et al. Retrograde delivery of photosensitizer (TPPp-O-b-GluOH)3 selectively potentiates its photodynamic activity. Bioconjug Chem 2008;19:532-8. (Pubitemid 351294926)
35. Couture O, Bannouf S, Montaldo G, et al. Ultrafast imaging of ultrasound contrast agents. Ultrasound Med Biol 2009;35:1908-16.
36. Brock-Fisher G, Poland M, Rafter P, Mooney M. Experimental observations of the sensitivity and frequency response of the power modulation technique for contrast imaging. In: Ten Cate FJ, de Jong N, Cosgrove DO, eds. Fifth Heart Centre European Symposium on Ultrasound Contrast Imaging; Rotterdam. 2000. p. 1-77.
37. Montaldo G, Tanter M, Bercoff J, et al. Coherent plane-wave compounding for very high frame rate ultrasonography and transient elastography. IEEE Ultr Ferro Freq Cont 2009;56:489-506.
38. Poirier C, van Effenterre D, Delord B, et al. Specific adsorption of functionalized colloids at the surface of living cells: A quantitative kinetic analysis of the receptor-mediated binding. Biochim Biophys Acta 2008;1778:2450-7.
39. Bouter A, Delord B, Dransart E, et al. Intracellular trafficking of Shiga toxin B-subunit functionalized spherulites. Biol Cell 2008; 100:717-25.
40. Rychak JJ, Graba J, Cheung AM, et al. Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesis. Mol Imaging 2007;6:289-96. (Pubitemid 350013534)
41. Couture O, Aubry JF, Tanter M, Fink M. Time-reversal focusing of therapeutic ultrasound on targeted microbubbles. Appl Phys Lett 2009;94:173901.