Long-term follow-up in composite tissue allotransplantation: In-depth study of five (hand and face) recipients

American Journal of Transplantation

Volumn 11, Issue 4, 2011, Pages 808-816

  Petruzzo, P ^a,b   Kanitakis, J ^a   Badet, L ^a   Pialat, J B ^a   Boutroy, S ^c   Charpulat, R ^c   Mouly, J ^a   Gazarian, A ^d   Lanzetta, M ^e   Brunet, M ^a   Devauchelle, B ^f   Testelin, S ^f   Martin, X ^a   Dubernard, J M ^a   Morelon, E ^a,g  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c Université des Sciences et Technologies de Lille   (France)

^d Polyclinique Orthopédique de Lyon ^*  (France)

^e Italian Institute of Hand Surgery   (Italy)

^f AMIENS UNIVERSITY HOSPITAL   (France)

^g UNIVERSITÉ DE LYON   (France)

Author keywords

Chronic transplant rejection; composite tissue allotransplantation; face allotransplantation; hand allotransplantation

Indexed keywords

CLOBETASOL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; STEROID; TACROLIMUS;

ADULT; ALLOTRANSPLANTATION; ARTICLE; BONE DENSITY; CHRONIC GRAFT REJECTION; CLINICAL ARTICLE; COMPOSITE GRAFT; COMPUTER ASSISTED TOMOGRAPHY; DENERVATION; ECHOGRAPHY; FACE SURGERY; FEMALE; FOLLOW UP; HAND SURGERY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LONG TERM CARE; MALE; MUSCLE HYPERTROPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIUS; SKIN FIBROSIS; SKIN STRUCTURE; TIBIA;

ADOLESCENT; ADULT; FACE; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HAND; HUMANS; MALE; MIDDLE AGED; ORGAN TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS; YOUNG ADULT;

EID: 79953234388     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2011.03469.x     Document Type: Article

References (18)

1. Jensen J, Mackinnon SE,. Composite tissue allotransplantation: A comprehensive review of the literature, part II. J Reconstr Microsurg 2000; 16: 141-157. (Pubitemid 30115353)
2. Swearingen B, Ravindra K, Xu H, Wu S, Breidenbach WC, Ildstad ST,. Science of composite tissue allotransplantation. Transplantation 2008; 86: 627-635.
3. Unadka JV, Schneeberger S, Horibe EH, et al,. Composite tissue vasculopathy and degeneration following multiple episodes of acute rejection in reconstructive surgery. Am J Transplant 2010; 10: 251-261.
4. Petruzzo P, Lanzetta M, Dubernard JM, et al,. The international registry on hand and composite tissue transplantation. Transplantation 2008; 86: 487-492.
5. Cendales LC, Kanitakis J, Schneeberger S, et al., The Banff 2007 working classification of skin-containing composite tissue allograft pathology. Am J Transplant 2008; 8: 1396-1400. (Pubitemid 351989486)
6. Kouwenhoven EA, IJzermans JN, de Bruin RW,. Etiology and pathophysiology of chronic transplant dysfunction. Transpl Int 2000; 13: 385-401.
7. Joosten SA, Sijpkens YW, van Kooten C, Paul LC,. Chronic renal allograft rejection: Pathophysiologic considerations. Kidney Int 2005; 68: 1-13. (Pubitemid 43181359)
8. Hillebrands JL, Rozing J,. Chronic transplant dysfunction and transplant arteriosclerosis: New insights into underlying mechanisms. Expert Rev Mol Med 2003; 5: 1-23.
9. Boutroy S, Bouxsein ML, Munoz F, Delmas PD,. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Met 2005; 90: 6508-6515. (Pubitemid 41759306)
10. Gummesson C, Ward M, Atroshi I,. The shortened disability of the arm, shoulder and hand questionnaire (Quick DASH): Validity and reliability based on responses within the full length DASH. BMC Musculoskeletal Disord 2006; 7: 1-7
11. Petruzzo P, Badet L, Gazarian A, et al,. Bilateral hand transplantation: Six years after the first case. Am J Transplant 2006; 6: 1718-1724. (Pubitemid 43945815)
12. Wagatsuma A,. Upregulation of gene encoding adipogenic transcriptional factors C/EBPalpha and PPARgamma2 in denervated muscle. Exp Physiol 2006; 91: 747-753. (Pubitemid 43944646)
13. Langhor HD,. Biochemical studies on muscles in neurogenic atrophies and central paralysis. Studies of trophic functions of neurons. Fortschr Med 1980; 98: 1512-1516.
14. Kanitakis J, McGregor B, Badet L, et al,. Absence of c4d deposition in human composite tissue (hands and face) allograft biopsies: An immunoperoxidase study. Transplantation. 2007; 84: 265-267. (Pubitemid 47205762)
15. Dubernard JM, Lengelé B, Morelon E, et al,. Outcomes 18 months after the first human partial face transplantation. N Engl J Med 2007; 357: 2451-2460. (Pubitemid 350272784)
16. Siemionow M, Izycki D, Ozer K, Ozmen S, Klimczak A,. Role of thymus in operational tolerance induction in limb allograft transplant model. Transplantation 2006; 15: 1568-1576. (Pubitemid 43890894)
17. Eljaafari A, Badet L, Kanitakis J, et al,. Isolation of regulatory T cells in the skin of a human hand-allograft, up to six years posttransplantation. Transplantation 2006; 27: 1764-1768. (Pubitemid 46035664)
18. Kanitakis J, Morelon E, Petruzzo P, Badet L, Dubernard JM,. Self-renewal capacity of human epidermal Langerhans cells: Observations made on a composite tissue allograft. Exp Dermatol 2011; 20: 145-146.