MicroRNA-192 and-215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro

Oncogene

Volumn 30, Issue 13, 2011, Pages 1577-1585

  Jin, Z ^a   Selaru, F M ^a   Cheng, Y ^a   Kan, T ^a   Agarwal, R ^a   Mori, Y ^a   Olaru, A V ^a   Yang, J ^a   David, S ^a   Hamilton, J P ^a   Abraham, J M ^a   Harmon, J ^a   Duncan, M ^a   Montgomery, E A ^a   Meltzer, S J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

ALCAM; gastric cancer; microRNA 192 and 215

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; MICRORNA; MICRORNA 192; MICRORNA 215; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INVASION; CELL CYCLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH CARCINOMA; STOMACH EPITHELIUM; UPREGULATION; WESTERN BLOTTING;

ANTIGENS, CD; APOPTOSIS; CELL ADHESION MOLECULES, NEURONAL; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; FETAL PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; UP-REGULATION;

EID: 79953225838     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.534     Document Type: Article

References (35)

1. Adiseshaiah P, Lindner DJ, Kalvakolanu DV, Reddy SP. (2007). FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo. Cancer Res 67: 6204-6211. (Pubitemid 47037501)
2. Agarwal R, Mori Y, Cheng Y, Jin Z, Olaru AV, Hamilton JP et al. (2009). Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. PLoS One 4: e8002.
3. Ando T, Yoshida T, Enomoto S, Asada K, Tatematsu M, Ichinose M et al. (2009). DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect. Int J Cancer 124: 2367-2374.
4. Bartel DP. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
5. Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T et al. (2008). p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res 68: 10094-10104.
6. Carbone M, Rizzo P, Grimley PM, Procopio A, Mew DJ, Shridhar V et al. (1997). Simian virus-40 large-T antigen binds p53 in human mesotheliomas. Nat Med 3: 908-912. (Pubitemid 27353453)
7. Georges SA, Biery MC, Kim SY, Schelter JM, Guo J, Chang AN et al. (2008). Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215. Cancer Res 68: 10105-10112.
8. Guo J, Miao Y, Xiao B, Huan R, Jiang Z, Meng D et al. (2009). Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol 24: 652-657.
9. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C et al. (2006). Cancer statistics, 2006. CA Cancer J Clin 56: 106-130.
10. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. (2007). Cancer statistics, 2007. CA Cancer J Clin 57: 43-66. (Pubitemid 46148091)
11. Jezierska A, Motyl T. (2009). Matrix Metalloproteinase-2 involvement in breast cancer progression: a mini-review. Med Sci Monit 15: RA32-RA40.
12. Jezierska A, Olszewski WP, Pietruszkiewicz J, Olszewski W, Matysiak W, Motyl T. (2006). Activated Leukocyte Cell Adhesion Molecule (ALCAM) is associated with suppression of breast cancer cells invasion. Med Sci Monit 12: BR245-BR256. (Pubitemid 44031636)
13. Khushalani N. (2008). Cancer of the esophagus and stomach. Mayo Clin Proc 83: 712-722. (Pubitemid 351810570)
14. Kim JH, Takahashi T, Chiba I, Park JG, Birrer MJ, Roh JK et al. (1991). Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines. J Natl Cancer Inst 83: 938-943.
15. Kim YK, Yu J, Han TS, Park SY, Namkoong B, Kim DH et al. (2009). Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res 37: 1672-1681.
16. Kimura Y, Noguchi T, Kawahara K, Kashima K, Daa T, Yokoyama S. (2004). Genetic alterations in 102 primary gastric cancers by comparative genomic hybridization: gain of 20q and loss of 18q are associated with tumor progression. Mod Pathol 17: 1328-1337. (Pubitemid 39472987)
17. Kristiansen G, Pilarsky C, Wissmann C, Stephan C, Weissbach L, Loy V et al. (2003). ALCAM/CD166 is up-regulated in low-grade prostate cancer and progressively lost in high-grade lesions. Prostate 54: 34-43. (Pubitemid 36043834)
18. Li Z, Zhan W, Wang Z, Zhu B, He Y, Peng J et al. (2006). Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasis. Biochem Biophys Res Commun 348: 229-237. (Pubitemid 44163504)
19. 0 UTR. Proc Natl Acad Sci USA 104: 9667-9672. (Pubitemid 47175324)
20. Motoyama K, Inoue H, Nakamura Y, Uetake H, Sugihara K, Mori M. (2008). Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. Clin Cancer Res 14: 2334-2340. (Pubitemid 351551065)
21. Noguchi T, Wirtz HC, Michaelis S, Gabbert HE, Mueller W. (2001). Chromosomal imbalances in gastric cancer. Correlation with histologic subtypes and tumor progression. Am J Clin Pathol 115: 828-834. (Pubitemid 32476708)
22. Ofori-Acquah SF, King JA. (2008). Activated leukocyte cell adhesion molecule: a new paradox in cancer. Transl Res 151: 122-128. (Pubitemid 351221436)
23. 0UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 30: 460-471. (Pubitemid 351672378)
24. Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, de Martino I et al. (2008). E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 13: 272-286. (Pubitemid 351318375)
25. Rosso O, Piazza T, Bongarzone I, Rossello A, Mezzanzanica D, Canevari S et al. (2007). The ALCAM shedding by the metallo-protease ADAM17/TACE is involved in motility of ovarian carcinoma cells. Mol Cancer Res 5: 1246-1253.
26. Shi XB, Tepper CG, White RW. (2008). Cancerous miRNAs and their regulation. Cell Cycle 7: 1529-1538. (Pubitemid 351881316)
27. Song B, Wang Y, Kudo K, Gavin EJ, Xi Y, Ju J. (2008). miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. Clin Cancer Res 14: 8080-8086.
28. Swart GW. (2002). Activated leukocyte cell adhesion molecule (CD166/ALCAM): developmental and mechanistic aspects of cell clustering and cell migration. Eur J Cell Biol 81: 313-321. (Pubitemid 34692942)
29. 0-untranslated region of receptor-interacting protein 140 (RIP140) mRNA and up-regulates its protein expression. Biochem J 424: 411-418.
30. Tsukamoto Y, Uchida T, Karnan S, Noguchi T, Nguyen LT, Tanigawa M et al (2008). Genome-wide analysis of DNA copy number alterations and gene expression in gastric cancer. J Pathol 216: 471-482.
31. van Kempen LC, Meier F, Egeblad M, Kersten-Niessen MJ, Garbe C, Weidle UH et al. (2004). Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis. J Invest Dermatol 122: 1293-1301. (Pubitemid 38651106)
32. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261. (Pubitemid 43271657)
33. Wang Z, He YL, Cai SR, Zhan WH, Li ZR, Zhu BH et al. (2008). Expression and prognostic impact of PRL-3 in lymph node metastasis of gastric cancer: its molecular mechanism was investigated using artificial microRNA interference. Int J Cancer 123: 1439-1447.
34. Xia L, Zhang D, Du R, Pan Y, Zhao L, Sun S et al. (2008). miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 123: 372-379. (Pubitemid 351842022)
35. 0-untranslated region and coding sequence. Genetica 137: 159-164.