Impaired glucose metabolism in Japanese patients with acromegaly is restored after successful pituitary surgery if pancreatic β-cell function is preserved

European Journal of Endocrinology

Volumn 164, Issue 4, 2011, Pages 467-473

  Kinoshita, Yuka ^a,b   Fujii, Hiroko ^a,c   Takeshita, Akira ^a,d   Taguchi, Manabu ^a,b   Miyakawa, Megumi ^a,d   Oyama, Kenich ^a   Yamada, Shozo ^a,d   Takeuchi, Yasuhiro ^a,d  

^a TORANOMON HOSPITAL   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^d Okinaka Memorial Institute for Medical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; HEMOGLOBIN A1C; SOMATOMEDIN C;

ACROMEGALY; ADULT; ARTICLE; BODY MASS; CELL FUNCTION; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; ENDOCRINE SURGERY; FEMALE; GLUCOSE TOLERANCE; GROWTH HORMONE BLOOD LEVEL; HUMAN; HYPOPHYSIS SURGERY; INSULIN RESISTANCE; INSULIN SENSITIVITY; JAPANESE; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; AGE; DISEASE ASSOCIATION; HORMONE DETERMINATION; TREATMENT OUTCOME;

ACROMEGALY; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; PITUITARY GLAND; RETROSPECTIVE STUDIES;

EID: 79953180947     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-1096     Document Type: Article

References (18)

1. Ben-Shlomo A & Melmed S. Acromegaly. Endocrinology and Metabolism Clinics of North America 2008 37 101-122. (doi:10.1016/j.ecl.2007.10.002)
2. Holdaway IM. Excess morality in acromegaly. Hormone Research 2007 68 (Supplement 5) 166-172. (doi:10.1159/000110617)
3. Colao A, Ferone D, Marzullo P & Lombardi G. Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocrine Reviews 2004 25 102-152. (doi:10.1210/er.2002-0022)
4. Resmini E, Minuto F, Colao A & Ferone D. Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities. Acta Diabetologica 2009 46 85-95. (doi:10.1007/s00592-009-0112-9)
5. Kreze A, Kreze-Spirova E & Mikulecky M. Risk factors for glucose intolerance in active acromegaly. Brazilian Journal of Medical and Biological Research 2001 34 1429-1433. (doi:10.1590/S0100-879X2001001100009)
6. Nabarro JD. Acromegaly. Clinical Endocrinology 1987 26 481-512. (doi:10.1111/j.1365-2265.1987.tb00805.x)
7. Kasayama S, Otsuki M, Takagi M, Saito H, Sumitani S, Kouhara H, Koga M, Saitoh Y, Ohnishi T & Arita N. Impaired β-cell function in the presence of reduced insulin sensitivity determines glucose tolerance status in acromegalic patients. Clinical Endocrinology 2000 52 549-555. (doi:10.1046/j.1365-2265.2000.00986.x)
8. Fukuoka H, Takahashi Y, Iida K, Kudo T, Nishizawa H, Imanaka M, Takeno R, Iguchi G, Takahashi K, Okimura Y, Kaji H & Chihara K. Low serum IGF-1/GH ratio is associated with abnormal glucose tolerance in acromegaly. Hormone Research 2008 69 165-171. (doi:10.1159/000112590)
9. Stelmachowska-Banas M, Zdunowski P & Zglicaynski W. Abnormalities in glucose homeostasis in acromegaly. Does the prevalence of glucose intolerance depend on the level of activity of the disease and the duration of the symptoms? Endokrynologia Polska 2009 60 20-24.
10. Puder JJ, Nilavar S, Post KD & Freda PU. Relationship between disease-related morbidity and biochemical markers of activity in patients with acromegaly. Journal of Clinical Endocrinology and Metabolism 2005 90 1972-1978. (doi:10.1210/jc.2004-2009)
11. Giustina A, Barkan A, Casanueva FF, Cavagnini F, Frohman L, Ho K, Veldhuis J, Wass J, Von Werder K & Melmed S. Criteria for cure of acromegaly: a consensus statement. Journal of Clinical Endocrinology and Metabolism 2000 85 526-529. (doi:10.1210/jc.85.2.526)
12. Levy JC, Matthews DR & Hermans MP. Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care 1998 21 2191-2192. (doi:10.2337/diacare.21.12.2191)
13. Wallace TM, Levy JC & Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004 27 1487-1495. (doi:10.2337/diacare.27.6.1487)
14. Seltzer HS, Allen EW, Herron AL Jr & Brennan MT. Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus. Journal of Clinical Investigation 1967 46 323-335. (doi:10.1172/JCI105534)
15. Hanley JA & McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982 143 29-36. (Pubitemid 12142173)
16. Hanley JA & McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983 148 839-843. (Pubitemid 13033817)
17. De Fronzo RA, Bonadonna RC & Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 1992 15 318-368. (doi:10.2337/diacare.15.3.318)
18. Funakoshi S, Fujimoto S, Hamasaki A, Fujiwara H, Fujita Y, Ikeda K, Hamamoto Y, Hosokawa M, Seino Y & Inagaki N. Analysis of factors influencing pancreatic β-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure. Diabetes Research and Clinical Practice 2008 82 353-358. (doi:10.1016/j.diabres.2008.09. 010)