Renal allograft failure in a hyperparathyroid patient following initiation of a calcimimetic

Nature Reviews Nephrology

Volumn 7, Issue 4, 2011, Pages 237-241

  Seikrit, Claudia ^a   Mühlfeld, Anja ^a   Groene, Hermann Josef ^b   Floege, Jürgen ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BASILIXIMAB; CALCIUM; CINACALCET; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROCHLOROTHIAZIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PARATHYROID HORMONE; PHOSPHATE; PHOSPHATE BINDING AGENT; PREDNISOLONE; TACROLIMUS;

ADULT; ANTIHYPERTENSIVE THERAPY; ARTICLE; CALCIUM BLOOD LEVEL; CASE REPORT; DIALYSIS; DIURETIC THERAPY; DRUG WITHDRAWAL; GRAFT FAILURE; HUMAN; HUMAN TISSUE; HYPERCALCEMIA; HYPERKALEMIA; HYPOCALCIURIA; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT; KIDNEY ALLOGRAFT FAILURE; KIDNEY BIOPSY; KIDNEY CALCIFICATION; KIDNEY FAILURE; KIDNEY GRAFT REJECTION; MALE; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROIDECTOMY; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; SECONDARY HYPERPARATHYROIDISM;

GRAFT SURVIVAL; HUMANS; HYPERPARATHYROIDISM, SECONDARY; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; NAPHTHALENES; NEPHROCALCINOSIS; POSTOPERATIVE COMPLICATIONS; TRANSPLANTATION, HOMOLOGOUS;

EID: 79953176253     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2010.169     Document Type: Article

References (25)

1. Evenepoel, P. et al. Natural history of parathyroid function and calcium metabolism after kidney transplantation: a single-centre study. Nephrol. Dial. Transplant. 19, 1281-1287 (2004). (Pubitemid 38628152)
2. Egbuna, O. I., Taylor, J. G., Bushinsky, D. A. & Zand, M. S. Elevated calcium phosphate product after renal transplantation is a risk factor for graft failure. Clin. Transplant. 21, 558-566 (2007). (Pubitemid 47177046)
3. Roodnat, J. I. et al. High pretransplant parathyroid hormone levels increase the risk for graft failure after renal transplantation. Transplantation 82, 362-367 (2006). (Pubitemid 44223035)
4. Evenepoel, P. et al. Calcium metabolism in the early posttransplantation period. Clin. J. Am. Soc. Nephrol. 4, 665-672 (2009).
5. Gwinner, W. et al. Early calcification of renal allografts detected by protocol biopsies: causes and clinical implications. Am. J. Transplant. 5, 1934-1941 (2005). (Pubitemid 41039868)
6. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int. Suppl. S1-S130 (2009).
7. Srinivas, T. R. et al. Improvement in hypercalcemia with cinacalcet after kidney transplantation. Clin. J. Am. Soc. Nephrol. 1, 323-326 (2006).
8. Kruse, A. E., Eisenberger, U., Frey, F. J. & Mohaupt, M. G. The calcimimetic cinacalcet normalizes serum calcium in renal transplant patients with persistent hyperparathyroidism. Nephrol. Dial. Transplant. 20, 1311-1314 (2005). (Pubitemid 41435024)
9. El-Amm, J. M. et al. Preliminary experience with cinacalcet use in persistent secondary hyperparathyroidism after kidney transplantation. Transplantation 83, 546-549 (2007).
10. Serra, A. L., Schwarz, A. A., Wick, F. H., Marti, H. P. & Wuthrich, R. P. Successful treatment of hypercalcemia with cinacalcet in renal transplant recipients with persistent hyperparathyroidism. Nephrol. Dial. Transplant. 20, 1315-1319 (2005). (Pubitemid 41430604)
11. Leca, N. et al. Early and severe hyperparathyroidism associated with hypercalcemia after renal transplant treated with cinacalcet. Am. J. Transplant. 6, 2391-2395 (2006). (Pubitemid 44359425)
12. Szwarc, I. et al. Cinacalcet chloride is efficient and safe in renal transplant recipients with posttransplant hyperparathyroidism. Transplantation 82, 675-680 (2006). (Pubitemid 44395239)
13. Serra, A. L. et al. Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients. Nephrol. Dial. Transplant. 22, 577-583 (2007). (Pubitemid 46189904)
14. Clinical Trials. Using cinacalcet to treat the hypophosphatemia of early kidney transplant [online], http://www.clinicaltrials.gov/ct2/show/NCT01011114? term=nct01011114&rank=1 (2009).
15. Clinical Trials. Post transplant study [online], http://www. clinicaltrials.gov/ct2/results?term=NCT00395902 (2007).
16. Peng, L. W., Logan, J. L., James, S. H., Scott, K. M. & Lien, Y. H. Cinacalcet-associated graft dysfunction and nephrocalcinosis in a kidney transplant recipient. Am. J. Med. 120, e7-e9 (2007). (Pubitemid 47313323)
17. Esposito, L. et al. Hypercalciuria induced by a high dose of cinacalcet in a renal-transplant recipient. Clin. Nephrol. 68, 245-248 (2007). (Pubitemid 47527446)
18. Borchhardt, K. A. et al. Cinacalcet increases calcium excretion in hypercalcemic hyperparathyroidism after kidney transplantation. Transplantation 86, 919-924 (2008).
19. Serra, A. L. et al. Pharmacokinetics and pharmacodynamics of cinacalcet in patients with hyperparathyroidism after renal transplantation. Am. J. Transplant. 8, 803-810 (2008). (Pubitemid 351347748)
20. Serra, A. L., Wuhrmann, C. & Wuthrich, R. P. Phosphatemic effect of cinacalcet in kidney transplant recipients with persistent hyperparathyroidism. Am. J. Kidney Dis. 52, 1151-1157 (2008).
21. Torres, A., Lorenzo, V. & Salido, E. Calcium metabolism and skeletal problems after transplantation. J. Am. Soc. Nephrol. 13, 551-558 (2002).
22. Boom, H. et al. Calcium levels as a risk factor for delayed graft function. Transplantation 77, 868-873 (2004). (Pubitemid 38436826)
23. Rayes, N. et al. Long-term results of subtotal vs total parathyroidectomy without autotransplantation in kidney transplant recipients. Arch. Surg. 143, 756-761 (2008).
24. Evenepoel, P., Claes, K., Kuypers, D. R., Debruyne, F. & Vanrenterghem, Y. Parathyroidectomy after successful kidney transplantation: a single centre study. Nephrol. Dial. Transplant. 22, 1730-1737 (2007). (Pubitemid 47073776)
25. Hebert, S. C. Bartter syndrome. Curr. Opin. Nephrol. Hypertens. 12, 527-532 (2003). (Pubitemid 37083114)