Early calcification of renal allografts detected by protocol biopsies: Causes and clinical implications

American Journal of Transplantation

Volumn 5, Issue 8, 2005, Pages 1934-1941

  Gwinner, Wilfried ^a   Suppa, Sylvia ^a   Mengel, Michael ^a   Hoy, Ludwig ^a   Kreipe, Hans H ^a   Haller, Hermann ^a   Schwarz, Anke ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Calcium; Graft outcome; Hyperparathyroidism; Kidney transplantation; Parathormone; Protocol biopsy

Indexed keywords

CALCINEURIN INHIBITOR; CALCIUM; PARATHYROID HORMONE;

ADULT; AGE DISTRIBUTION; ANAMNESIS; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM HOMEOSTASIS; COMORBIDITY; CONTROLLED STUDY; DIALYSIS; FEMALE; GRAFT SURVIVAL; HLA MATCHING; HUMAN; HUMAN TISSUE; HYPERPARATHYROIDISM; KIDNEY ALLOGRAFT; KIDNEY CALCIFICATION; KIDNEY DISEASE; KIDNEY TUBULE DAMAGE; MAJOR CLINICAL STUDY; MALE; PARAMETER; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; SEX DIFFERENCE; TREATMENT INDICATION;

ADULT; BIOPSY; CALCINOSIS; CALCIUM; FEMALE; GRAFT SURVIVAL; HUMANS; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; KIDNEY TUBULES; MALE; MIDDLE AGED; PARATHYROID HORMONE; RISK FACTORS; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 22844441066     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2005.00938.x     Document Type: Article

References (30)

1. Iguchi S, Nishi S, Shinbo J et al. Intratubular calcification in a post-renal transplanted patient with secondary hyperparathyroidism. Clin Transplant 2001; 15: 51-54.
2. Hartmann A, Charania B, Sund S, Holdaas H, Fauchald P, Flatmark A. Interstitial nephritis with extensive calcium deposits as a cause of renal allograft failure. Nephrol Dial Transplant 1991; 6: 984-988.
3. Ferguson RK, Reed DM, Barber KG, Bannett AD, Raja RM. Sodium-losing nephropathy and nephrocalcinosis after transplantation. Am J Kidney Dis 1985; 5: 206-210.
4. Zazgornik J, Biesenbach G, Grafinger P et al. Rapid calcification of the renal graft in a 38-year old woman with type 1 diabetes. Nephrol Dial Transplant 1996; 11: 545-547.
5. Leapman SB, Vidne BA, Butt KM, Waterhouse K, Kountz SL. Nephrolithiasis and nephrocalcinosis after renal transplantation: a case report and review of the literature. J Urol 1976; 115: 129-132.
6. Daly BD, Goldberg PA, Krebs TL, Wong-You-Cheong JJ, Drachenberg CI. End stage renal transplant failure: allograft appearances on CT. Clin Radiol 1997; 52: 849-853.
7. Boom H, Mallat MJ, de Fijter JW, Paul LC, Bruijn JA, van Es LA. Calcium levels as a risk factor for delayed graft function. Transplantation 2004; 77: 868-873.
8. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR. The natural history of chronic allograft nephropathy. N Engl J Med 2003; 349: 2326-2333.
9. Mihatsch MJ, Thiel G, Basler V et al. Morphological patterns in cyclosporine-treated renal transplant recipients. Transplant Proc 1985; 17: 101-116.
10. Racusen LC, Colvin RB, Solez K et al. Antibody-mediated rejection criteria-an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant 2003; 3: 708-714.
11. Von Kossa J. Ueber die im Organsismus kuenstlich erzeugbaren Verkalkungen. Beitr Pathol Anat Allg Pathol 1901; 29: 163.
12. Evenepoel P, Claes K, Kuypers D, Maes B, Bammens B, Vanrenterghem Y. Natural history of parathyroid function and calcium metabolism after kidney transplantation: a single-centre study. Nephrol Dial Transplant 2004; 19: 1281-1287.
13. Messa P, Sindici C, Cannella G et al. Persistent secondary hyperparathyroidism after renal transplantation. Kidney Int 1998; 54: 1704-1713.
14. Cundy T, Kanis JA, Heynen G, Morris PJ, Oliver DO. Calcium metabolism and hyperparathyroidism after renal transplantation. Q J Med 1983; 52: 67-78.
15. David DS, Sakai S, Brennan BL et al. Hypercalcemia after renal transplantation. Long-term follow-up data. N Engl J Med 1973; 289: 398-401.
16. Alfrey AC, Jenkins D, Groth CG, Schorr WS, Gecelter L, Ogden DA. Resolution of hyperparathyroidism, renal osteodystrophy and metastatic calcification after renal homotransplantation. N Engl J Med 1968; 279: 1349-1356.
17. McIntosh DA, Peterson EW, McPhaul JJ Jr. Autonomy of parathyroid function after renal homotransplantation. Ann Intern Med 1966; 65: 900-907.
18. Bonarek H, Merville P, Bonarek M et al. Reduced parathyroid functional mass after successful kidney transplantation. Kidney Int 1999; 56: 642-649.
19. Heering P, Degenhardt S, Grabensee B. Tubular dysfunction following kidney transplantation. Nephron 1996; 74: 501-511.
20. Smith KD, Wrenshall LE, Nicosia RF et al. Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use. J Am Soc Nephrol 2003; 14: 1037-1045.
21. Andoh TF, Burdmann EA, Fransechini N, Houghton DC, Bennett WM. Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506. Kidney Int 1996; 50: 1110-1117.
22. Milliner DS, Zinsmeister AR, Lieberman E, Landing B. Soft tissue calcification in pediatric patients with end-stage renal disease. Kidney Int 1990; 38: 931-936.
23. National Kidney Foundation. NKF K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Guideline 6. Serum calcium and calcium-phosphorus product. Internet access: http:/www.kidney.org/ professionals/ kdoqi/index.cfm.
24. Locatelli F. The need for better control of secondary hyperparathyroidism. Nephrol Dial Transplant 2004; 19: V15-V19.
25. National Kidney Foundation. NKF K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Guideline 16. Bone disease in the kidney transplant recipient. Internet access: http:/www.kidney.org/professionals/ kdoqi/index.cfm.
26. Ketteler M, Bongartz P, Westenfeld R et al. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet 2003; 361: 827-833.
27. Moe SM, O'Neill KD, Duan D et al. Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins. Kidney Int 2002; 61: 638-647.
28. Canfield AE, Farrington C, Dziobon MD et al. The involvement of matrix glycoproteins in vascular calcification and fibrosis: an immunohistochemical study. J Pathol 2002; 196: 228-234.
29. National Kidney Foundation. NKF K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Guideline 14. Parathyroidectomy in patients with CKD. Internet access: http:/www.kidney.org/ professionals/kdoqi/index.cfm.
30. EBPG Expert Group on Renal Transplantation European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.8. Bone disease. Nephrol Dial Transplant 2002; 17: 43-48.