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Volumn 46, Issue 5, 2011, Pages 1849-1856

Identification of novel potential antibiotics for tuberculosis by in silico structure-based drug screening

Author keywords

Antibiotic; Enoyl acyl carrier protein reductase; Extensively drug resistant TB (XDR TB); In silico structure based drug screening; Mycobacterium tuberculosis (MTB); Virtual screening

Indexed keywords

2 ([4 (2 FURYLMETHYL) 5 (2 METHYLPHENYL) 4H 1,2,4 TRIAZOL 3 YL]THIO) N (2 METHOXYDIBENZO[B,D]FURAN 3 YL)ACETAMIDE; 2 ACETYL 1,4 PHENYLENEBIS[4 (1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)BUTANOATE]; 2,4 DICHLORO N (1 [4 ETHYL 5 (2 OXO 2 [(4 PHENYL 1,3 THIAZOL 2 YL)AMINO]ETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL]ETHYL)BENZAMIDE; 2,4 DICHLORO N (1 [4 METHYL 5 ((2 [(5 METHYL 4 PHENYL 1,3 THIAZOL 2 YL)AMINO] 2 OXOETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL]ETHYL)BENZAMIDE; 2,4 DICHLORO N ([4 ETHYL 5 ((2 [(5 METHYL 4 PHENYL 1,3 THIAZOL 2 YL)AMINO] 2 OXOETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL]METHYL)BENZAMIDE; 4 (9,11 DIOXO 6,7,8,9,10,11 HEXAHYDRO 5H INDENO[1,2 B]QUINOLIN 10 YL)PHENYL (1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)ACETATE; 4 CHLORO N [(4 METHYL 5 ([2 OXO 2 (10H PHENOTHIAZIN 10 YL)ETHYL]THIO) 4H 1,2,4 TRIAZOL 3 YL)METHYL]BENZAMIDE; ANTIBIOTIC AGENT; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); ETHYL 4 (([(5 ([(3,4 DICHLOROBENZYL)THIO]METHYL) 4 METHYL 4H 1,2,4 TRIAZOL 3 YL)THIO]ACETYL)AMINO) BENZOATE; METHYL 3 ([N [4 (BENZYLOXY)PHENYL] N (METHYLSULFONYL)GLYCYL]AMINO) 4 CHLOROBENZOATE; METHYL 4 CHLORO 3 ([N (2,3 DIHYDRO 1,4 BENZODIOXIN 6 YLSULFONYL) N (4 FLUOROPHENYL)GLYCYL]AMINO)BENZOATE; N (1 [4 ETHYL 5 ((2 [(5 METHYL 4 PHENYL 1,3 THIAZOL 2 YL)AMINO] 2 OXOETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL] 2 METHYLPROPYL) 4 METHYLBENZAMIDE; N (1 [4-ETHYL 5 ((2 [(5 METHYL 4 PHENYL 1,3 THIAZOL 2 YL)AMINO] 2 OXOETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL] 2 METHYLPROPYL) 4 METHYLBENZAMIDE; N (2 [4 ALLYL 5 ((2 OXO 2 [(4 PHENYL 1,3 THIAZOL 2 YL)AMINO]ETHYL)THIO) 4H 1,2,4 TRIAZOL 3 YL]ETHYL) 4 METHYLBENZAMIDE; N (4 ([(2,4 DIMETHOXYPHENYL)AMINO]SULFONYL)PHENYL) 2 (2 OXOBENZO[CD]INDOL 1 (2H) YL)ACETAMIDE; N (4 (BENZYLOXY)PHENYL)N (2 [4 (3 CHLOROPHENYL) 1 PIPERAZINYL] 2 OXOETHYL)METHANESULFONAMIDE; N 1 (1,5 DIMETHYL 3 OXO 2 PHENYL 2,3 DIHYDRO 1H PYRAZOL 4 YL)N 2 (4 PHENOXYPHENYL)N 2 (PHENYLSULFONYL)GLYCINAMIDE; N 1 ADAMANTYL 2 ([4 ANILINO 6 (4 MORPHOLINYL) 1,3,5 TRIAZIN 2 YL]THIO)ACETAMIDE; N 2 (4 CHLOROPHENYL)N 2 [(3,4 DIMETHOXYPHENYL)SULFONYL]N 1 [4 (1 PYRROLIDINYLSULFONYL)PHENYL]GLYCINAMIDE; N,N' BIS (4 [(BENZYLAMINO)CARBONYL]PHENYL)MALONAMIDE; N,N'BIS (2 PHENYLETHYL) 1,5 NAPHTHALENEDISULFONAMIDE; UNCLASSIFIED DRUG;

EID: 79953175238     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.02.047     Document Type: Article
Times cited : (21)

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