Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice

Journal of Immunological Methods

Volumn 367, Issue 1-2, 2011, Pages 27-32

  Göbel, Kerstin ^a   Bittner, Stefan ^b   Ruck, Tobias ^b   Budde, Thomas ^a   Wischmeyer, Erhard ^b   Döring, Frank ^b   Wiendl, Heinz ^a   Meuth, Sven G ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Active EAE; C3H; PLP

Indexed keywords

MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PROTEOLIPID PROTEIN;

ACTIVE IMMUNIZATION; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MOUSE; NONHUMAN; PARALYSIS; PRIORITY JOURNAL;

ANIMALS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MYELIN PROTEOLIPID PROTEIN; PEPTIDE FRAGMENTS; VACCINATION;

ANIMALIA; MUS; RODENTIA;

EID: 79953165319     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2010.12.018     Document Type: Article

References (35)

1. Amor S., Baker D., Groome N., Turk J.L. Identification of a major encephalitogenic epitope of proteolipid protein (residues 56-70) for the induction of experimental allergic encephalomyelitis in Biozzi AB/H and nonobese diabetic mice. J. Immunol. 1993, 150:5666-5672.
2. Amor S., Groome N., Linington C., Morris M.M., Dornmair K., Gardinier M.V., Matthieu J.M., Baker D. Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. J. Immunol. 1994, 153:4349-4356.
3. Bittner S., Meuth S.G., Gobel K., Melzer N., Herrmann A.M., Simon O.J., Weishaupt A., Budde T., Bayliss D.A., Bendszus M., Wiendl H. TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. Brain 2009, 132:2501-2516.
4. Brabb T., von Dassow P., Ordonez N., Schnabel B., Duke B., Goverman J. In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity. J. Exp. Med. 2000, 192:871-880.
5. Clark R.B., Grunnet M.L., Lingenheld E.G. The generation of encephalitogenic T cell lines from experimental allergic encephalomyelitis-resistant strains of mice. Int. Immunol. 1997, 9:1415-1422.
6. Cross A.H., O'Mara T., Raine C.S. Chronologic localization of myelin-reactive cells in the lesions of relapsing EAE: implications for the study of multiple sclerosis. Neurology 1993, 43:1028-1033.
7. Denic A., Johnson A.J., Bieber A.J., Warrington A.E., Rodriguez M., Pirko I. The Relevance of Animal Models in Multiple Sclerosis Research. Pathophysiology 2011, 18:21-29.
8. Duong T.T., Finkelman F.D., Singh B., Strejan G.H. Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains. J. Neuroimmunol. 1994, 53:101-107.
9. Fritz R.B., Skeen M.J., Chou C.H., Garcia M., Egorov I.K. Major histocompatibility complex-linked control of the murine immune response to myelin basic protein. J. Immunol. 1985, 134:2328-2332.
10. Greer J.M., Kuchroo V.K., Sobel R.A., Lees M.B. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. J. Immunol. 1992, 149:783-788.
11. Greer J.M., Sobel R.A., Sette A., Southwood S., Lees M.B., Kuchroo V.K. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. J. Immunol. 1996, 156:371-379.
12. Greer J.M., Csurhes P.A., Cameron K.D., McCombe P.A., Good M.F., Pender M.P. Increased immunoreactivity to two overlapping peptides of myelin proteolipid protein in multiple sclerosis. Brain 1997, 120(Pt 8):1447-1460.
13. Hickey W.F. Migration of hematogenous cells through the blood-brain barrier and the initiation of CNS inflammation. Brain Pathol. 1991, 1:97-105.
14. Kerlero de Rosbo N., Mendel I., Ben-Nun A. Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: preliminary analysis of MOG T cell epitopes. Eur. J. Immunol. 1995, 25:985-993.
15. Krishnamoorthy G., Wekerle H. EAE: an immunologist's magic eye. Eur. J. Immunol. 2009, 39:2031-2035.
16. Lando Z., Teitelbaum D., Arnon R. Effect of cyclophosphamide on suppressor cell activity in mice unresponsive to EAE. J. Immunol. 1979, 123:2156-2160.
17. Lebar R., Vincent C. Tentative identification of a second central nervous system myelin membrane autoantigen (M2) by a biochemical comparison with the basic protein (BP). J. Neuroimmunol. 1981, 1:367-389.
18. Levine S., Sowinski R. Experimental allergic encephalomyelitis in inbred and outbred mice. J. Immunol. 1973, 110:139-143.
19. Linington C., Bradl M., Lassmann H., Brunner C., Vass K. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am. J. Pathol. 1988, 130:443-454.
20. Linnington C., Webb M., Woodhams P.L. A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody. J. Neuroimmunol. 1984, 6:387-396.
21. Martenson R.E., Deibler G.E., Kies M.W. Microheterogeneity of guinea pig myelin basic protein. J. Biol. Chem. 1969, 244:4261-4267.
22. Mendel I., Kerlero de Rosbo N., Ben-Nun A. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. Eur. J. Immunol. 1995, 25:1951-1959.
23. Muller D.M., Pender M.P., Greer J.M. A neuropathological analysis of experimental autoimmune encephalomyelitis with predominant brain stem and cerebellar involvement and differences between active and passive induction. Acta Neuropathol. 2000, 100:174-182.
24. Muller D.M., Pender M.P., Greer J.M. Blood-brain barrier disruption and lesion localization in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement. J. Neuroimmunol. 2005, 160:162-169.
25. Olitsky P.K., Tal C. Acute disseminated encephalomyelitis produced in mice by brain proteolipide (Folch-Lees). Proc. Soc. Exp. Biol. Med. 1952, 79:50-53.
26. Rivers T.M., Sprunt D.H., Berry G.P. Observations on attempts to produce acute disseminated encephalomyelitis in monkeys. J. Exp. Med. 1933, 58:39-53.
27. Schuhmann M.K., Stegner D., Berna-Erro A., Bittner S., Braun A., Kleinschnitz C., Stoll G., Wiendl H., Meuth S.G., Nieswandt B. Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation. J. Immunol. 2009, 184:1536-1542.
28. Seamons A., Perchellet A., Goverman J. Immune tolerance to myelin proteins. Immunol. Res. 2003, 28:201-221.
29. Sobel R.A., Tuohy V.K., Lu Z.J., Laursen R.A., Lees M.B. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J. Neuropathol. Exp. Neurol. 1990, 49:468-479.
30. Sospedra M., Martin R. Immunology of multiple sclerosis. Annu. Rev. Immunol. 2005, 23:683-747.
31. Stromnes I.M., Goverman J.M. Active induction of experimental allergic encephalomyelitis. Nat. Protoc. 2006, 1:1810-1819.
32. Stromnes I.M., Cerretti L.M., Liggitt D., Harris R.A., Goverman J.M. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat. Med. 2008, 14:337-342.
33. Traugott U., Raine C.S., McFarlin D.E. Acute experimental allergic encephalomyelitis in the mouse: immunopathology of the developing lesion. Cell. Immunol. 1985, 91:240-254.
34. Tuohy V.K., Sobel R.A., Lu Z., Laursen R.A., Lees M.B. Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice. J. Neuroimmunol. 1992, 39:67-74.
35. Williams R.M., Moore M.J. Linkage of susceptibility to experimental allergic encephalomyelitis to the major histocompatibility locus in the rat. J. Exp. Med. 1973, 138:775-783.