Genetic and immunological processes in the pathomechanism of gluten-sensitive enteropathy and associated metabolic bone disorders

Autoimmunity Reviews

Volumn 10, Issue 6, 2011, Pages 336-340

  Vereckei, Edit ^a   Szodoray, Peter ^b   Poor, Gyula ^a   Kiss, Emese ^a  

^a NATIONAL INSTITUTE OF RHEUMATOLOGY AND PHYSIOTHERAPY   (Hungary)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Bone metabolism; Celiac disease; Cytokines; Genetic predisposition; Immunological background

Indexed keywords

ENDOMYSIUM ANTIBODY; GLUTEN; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANTIBODY DETECTION; APHTHOUS STOMATITIS; CELIAC DISEASE; CLINICAL FEATURE; CYTOKINE PRODUCTION; DERMATITIS HERPETIFORMIS; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; GENETIC PREDISPOSITION; GLUTEN FREE DIET; HISTOPATHOLOGY; HUMAN; IMMUNOGLOBULIN A DEFICIENCY; IMMUNOGLOBULIN A NEPHROPATHY; INSULIN DEPENDENT DIABETES MELLITUS; JEJUNUM BIOPSY; METABOLIC BONE DISEASE; NONHUMAN; PATHOGENESIS; REVIEW; T LYMPHOCYTE;

BONE DISEASES, METABOLIC; CELIAC DISEASE; GLUTENS; HUMANS;

EID: 79953164292     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2010.12.001     Document Type: Review

References (40)

1. Fasano A., Catassi C. Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum. Gastroenterology 2001, 6:1527-1528.
2. Fernández A., González L., de-la-Fuente J. Coeliac disease: clinical features in adult populations. Rev Esp Enferm Dig 2010, 8:466-471.
3. Setty M., Hormaza L., Guandalini S. Celiac disease: risk assessment, diagnosis, and monitoring. Mol Diagn Ther 2008, 5:289-298.
4. Ensari A. Gluten-sensitive enteropathy [celiac disease]: controversies in diagnosis and classification. Arch Pathol Lab Med 2010, 6:826-836.
5. De Nitto D., Monteleone I., Franzè E., et al. Involvement of interleukin-15 and interleukin-21, two gamma-chain-related cytokines, in celiac disease. World J Gastroenterol 2009, 37:4609-4614.
6. Sapone A., Lammers K.M., Mazzarella G., et al. Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. Int Arch Allergy Immunol 2009, 1:75-80.
7. Kapitány A., Tóth L., Tumpek J., et al. Diagnostic significance of HLA-DQ typing in patients with previous coeliac disease diagnosis based on histology alone. Aliment Pharmacol Ther 2006, 9:1395-1402.
8. Szodoray P., Barta Z., Lakos G., Szakáll S., Zeher M. Coeliac disease in Sjögren's syndrome - a study of 111 Hungarian patients. Rheumatol Int 2004 Sep, 24(5):278-282.
9. Shakeri R., Zamani F., Sotoudehmanesh R., et al. C Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis. Gastroenterol 2009 Jun 17, 9:44.
10. Volta U. Liver dysfunction in celiac disease. Minerva Med 2008 Dec, 99(6):619-629.
11. Bourne J.T., Kumar P., Huskisson E.C. Arthritis and coeliac disease. Ann Rheum Dis 1985, 9:592-598.
12. Vereckei E., Mester Á., Hodinka L., et al. Back pain and sacroiliitis in long-standing adult celiac disease: a cross-sectional and follow-up study. Rheumatol Int 2009, jun.6.
13. Usai P., Boi M.F., Piga M., et al. Adult celiac disease is frequently associated with sacroiliitis. Dig Dis Sci 1995, 9:1906-1908.
14. Vereckei E., Mester Á., Hodinka L., et al. Study of inflammatory musculoskeletal disorders and bone metabolism of patients with gluten-sensitive enteropathy. Magy Reumatol 2007, 1:31-41.
15. Capriles V.D., Martini L.A., Arêas J.A. Metabolic osteopathy in celiac disease: importance of a gluten-free diet. Nutr Rev 2009, 10:599-606.
16. Bianchi M.L., Bardella M.T. Bone in celiac disease. Osteoporos Int 2008, 12:1705-1716.
17. Pazianas M., Butcher G.P., Subhani J.M., et al. Calcium absorption and bone mineral density in celiacs after long term treatment with gluten-free diet and adequate calcium intake. Osteoporos Int 2005, 1:56-63.
18. Pazianas M., Butcher G.P., Subhani J.M., et al. Risk of osteoporosis in endocrine disorders and celiac disease. Ann Ist Super Sanità 2007, 4:430-433.
19. Bianchi M.L., Bardella M.T. Bone and celiac disease. Calcif Tissue Int 2002, 6:465-471.
20. Kavuncu V., Dundar U., Ciftci I.H., et al. Is there any requirement for celiac disease screening routinely in postmenapausal women with osteoporosis?. Rheumatol Int 2009, 7:841-845.
21. Vogelsang H., Suk E.K., Janisiw M., et al. Calcaneal ultrasound attenuation and vitamin-D-receptor genotypes in celiac disease. Scand J Gastroenterol 2000, 2:172-176.
22. San-Pedro J.I., Bilbao J.R., Perez de Nanclares G., et al. Heterogeneity of vitamin D receptor gene association with celiac disease and type 1 diabetes mellitus. Autoimmunity 2005, 6:439-644.
23. Riches P.L., McRorie E., Fraser W.D., et al. Osteoporosis associated with neutralizing autoantibodies against osteoprotegerin. N Engl J Med 2009, 15:1459-1465.
24. Sugai E., Cherñavsky A., Pedreira S., et al. Bone-specific antibodies in sera from patients with celiac disease: characterization and implications in osteoporosis. J Clin Immunol 2002, 6:353-362.
25. Moreno M.L., Crusius J.B., Cherñavsky A., et al. The IL-1 gene family and bone involvement in celiac disease. Immunogenetics 2005, 8:618-620.
26. Stazi A.V., Trinti B. Risk of osteoporosis in endocrine disorders and celiac disease. Ann Ist Super Sanità 2007, 4:430-433.
27. Duerksen D.R., Leslie W.D. Positive celiac disease serology and reduced bone mineral density in adult women. Can J Gastroenterol 2010, 2:103-107.
28. Zofková I. Celiac disease and its relation to bone metabolism. Cas Lék Cesk 2009, 6:246-248.
29. Tilg H., Moschen A.R., Kaser A., et al. Gut, inflammation and osteoporosis: basic and clinical concepts. Gut 2008, 5:684-694.
30. Lerner A. New therapeutic strategies for celiac disease. Autoimmun Rev 2010, 3:144-147.
31. Lindfors K., Mäki M., Kaukinen K. Transglutaminase 2-targeted autoantibodies in celiac disease: pathogenetic players in addition to diagnostic tools?. Autoimmun Rev 2010, 9:744-749.
32. Logan I., Bowlus C.L. The geoepidemiology of autoimmune intestinal diseases. Autoimmun Rev 2010, 9:A372-A378.
33. Lerner A. New therapeutic strategies for celiac disease. Autoimmun Rev 2010, 9:144-147.
34. Plot L., Amital H. Infectious associations of celiac disease. Autoimmun Rev 2009, 8:316-319.
35. Briani C., Samaroo D., Alaedini A. Celiac disease: from gluten to autoimmunity. Autoimmun Rev 2008, 7:644-650.
36. Shaoul R., Lerner A. Associated autoantibodies in celiac disease. Autoimmun Rev 2007, 6:559-565.
37. Periolo N., Cherńavsky A.C. Coeliac disease. Autoimmun Rev 2006, 5:202-208.
38. Freitag T., Schulze-Koops H., Niedobitek G., Melino G., Schuppan D. The role of the immune response against tissue transglutaminase in the pathogenesis of coeliac disease. Autoimmun Rev 2004, 3:13-20.
39. Reif S., Lerner A. Tissue transglutaminase - the key player in celiac disease: a review. Autoimmun Rev 2004, 3:40-45.
40. Bizzaro N., Villalta D., Tonutti E., Tampoia M., Bassetti D., Tozzoli R. Association of celiac disease with connective tissue diseases and autoimmune diseases of the digestive tract. Autoimmun Rev 2003, 2:358-363.