Neural respiratory drive in patients with COPD during exercise tests

Respiration

Volumn 81, Issue 4, 2011, Pages 294-301

  Luo, Y M ^a   Li, R F ^a   Jolley, C ^b   Wu, H D ^a   Steier, J ^b   Moxham, J ^b   Zhong, N S ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease; Diaphragm; Neural respiratory drive; Respiratory muscle function

Indexed keywords

ADULT; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; DISEASE SEVERITY; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; HUMAN; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RESPIRATORY DRIVE; TREADMILL EXERCISE;

DIAPHRAGM; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMANS; INHALATION; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATION; TOTAL LUNG CAPACITY;

EID: 79953162872     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000317136     Document Type: Article

References (25)

1. Mador MJ, Dahuja M: Mechanisms for diaphragmatic fatigue following high-intensity leg exercise. Am J Respir Crit Care Med 1996; 154: 1484-1489. (Pubitemid 26391202)
2. Polkey MI, Kyroussis D, Keilty SE, Hamnegard CH, Mills GH, Green M, Moxham J: Exhaustive treadmill exercise does not reduce twitch transdiaphragmatic pressure in patients with COPD. Am J Respir Crit Care Med 1995; 152: 959-964.
3. Kyroussis D, Polkey MI, Hamnegard CH, et al: Respiratory muscle activity in patients with COPD walking to exhaustion with and without pressure support. Eur Respir J 2000; 15: 649-655. (Pubitemid 30196290)
4. O'Donnell DE, Revill SM, Webb KA: Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 164: 770-777. (Pubitemid 32881912)
5. Olséna MF, Westerdahlb E: Positive expiratorypressure in patients with chronic obstructive pulmonary disease: a systematic review. Respiration 2009; 77: 110-118.
6. Krieger BP: Hyperinflation and intrinsic positive end-expiratory pressure: less room to breathe. Respiration 2009; 77: 344-350.
7. Clini EM, Crisafulli E: Exercise capacity as a pulmonary rehabilitation outcom. Respiration 2009; 77: 121-128.
8. Luo YM, Hart N, Mustfa N, Lyall RA, Polkey MI, Moxham J: Effect of diaphragm fatigue on neural respiratory drive. J Appl Physiol 2001; 90: 1691-1699. (Pubitemid 32336449)
9. Luo YM, Moxham J: Measurement of neural respiratory drive in patients with COPD. Respir Physiol Neurobiol 2005; 146: 165-174. (Pubitemid 40349087)
10. Sinderby C, Spahija J, Beck J, Kaminski D, Yan S, Comtois N, Sliwinski P: Diaphragm activation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 163: 1637-1641. (Pubitemid 32578769)
11. Luo YM, Wu HD, Tang J, Jolley C, Steier J, Moxham J, Zhong NS, Polkey MI: Neural respiratory drive during apnoeic events in obstructive sleep apnoea. Eur Respir J 2008; 31: 650-657.
12. Casas A, Vilaro J, Rabinovich R, Mayer A, Barberà JA, Rodriguez-Roisin R, Roca J: Encouraged 6 min walking test indicates maximum sustainable exercise in COPD patients. Chest 2005; 128: 55-61. (Pubitemid 40994454)
13. Luo YM, J Moxham, MI Polkey: Diaphragm electromyography using an esophagealcatheter; current concepts. Clin Sci 2008; 115: 233-244.
14. O'Donnell DE, Webb KA: Exertional breathlessness in patients with chronic airflow limitation. Am Rev Respir Dis 1993; 148: 1351-1357. (Pubitemid 23326038)
15. Aldrich TK, Spiro P: Maximal inspiratory pressure: does reproducibility indicate full effort? Thorax 1995; 50: 40-43 .
16. Mador MJ, Kufel TJ, Pineda LA, Sharma GK: Diaphragmatic fatigue and high-intensity exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 161: 118-123. (Pubitemid 30055912)
17. Man WD, Mustfa N, Nikoletou D, Kaul S, Hart N, Rafferty GF, Donaldson N, Polkey MI, Moxham J: Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD. Thorax 2004; 59: 471-476. (Pubitemid 38797518)
18. Polkey MI, Hamnegård CH, Hughes PD, Rafferty GF, Green M, Moxham J: Influence of acute lung volume change on contractile properties of human diaphragm J Appl Physiol 1998; 85: 1322-1328. (Pubitemid 28465059)
19. Ninane V, Rypens F, Yernault JC, De Troyer A: Abdominal muscle use during breathing in patients with chronic airflow obstruction. Am Rev Respir Dis 1992; 146: 16-21.
20. Casas A, Vilaro J, Rabinovich R, Mayer A, Barberà JA, Rodriguez-Roisin R, Roca J: Encouraged 6 min walking test indicates maximum sustainable exercise in COPD patients. Chest 2005; 128: 55-61. (Pubitemid 40994454)
21. Oga T, Nishimura K, Tsukino M, Hajiro T, Ikeda A, Izumi T: The effects of oxitropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease: a comparison of three different exercise tests. Am J Respir Crit Care Med 2000; 161: 1897-1901. (Pubitemid 30418126)
22. Killian KL, Campbell ME: Dyspnea; in Roussos Ch (ed): The Thorax. New York, Marcel Dekker, 1995, pp 1709-1747.
23. Bellemare F, Bigland-Ritchie B: Central components of diaphragmatic fatigue assessed by phrenic nerve stimulation. J Appl Physiol 1987; 62: 1307-1316. (Pubitemid 17073937)
24. Ferguson GT: Respiratory failure due to altered central drive during inspiratory loading in rabbits. Respir Physiol 1995; 99: 75-87.
25. Sassoon CS, Gruer SE, Sieck GC: Temporal relationships of ventilatory failure, pump failure, and diaphragm fatigue. J Appl Physiol 1996; 81: 238-245. (Pubitemid 26255515)