Increased breadth and depth of cytotoxic T Lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Rolland, Morgane ^a,f   Frahm, Nicole ^b,g   Nickle, David C ^a   Jojic, Nebojsa ^c   Deng, Wenjie ^a   Allen, Todd M ^b   Brander, Christian ^b,c,d   Heckerman, David E ^e   Mullins, James I ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e MICROSOFT RESEARCH   (United States)

^f HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

^g Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; B NEF PROTEIN; CD8 ANTIGEN; EPITOPE; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEF PROTEIN; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ANTIGEN; PEPTIDE;

ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CROSS REACTION; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN VARIANT; VIRUS CELL INTERACTION; VIRUS STRAIN; AMINO ACID SEQUENCE; CHEMISTRY; CONSENSUS SEQUENCE; ENZYME LINKED IMMUNOSPOT ASSAY; GENETICS; IMMUNOLOGY; MUTATION;

CERCOPITHECINE HERPESVIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; BASE SEQUENCE; CONSENSUS SEQUENCE; CROSS REACTIONS; ENZYME-LINKED IMMUNOSPOT ASSAY; EPITOPES; HIV-1; HUMANS; INTERFERON-GAMMA; MUTATION; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PEPTIDES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 79953142380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017969     Document Type: Article

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