Depression, osteoporosis, serotonin and cell membrane viscosity between biology and philosophical anthropology

Annals of General Psychiatry

Volumn 10, Issue , 2011, Pages

  Cocchi, Massimo ^a,b,d   Tonello, Lucio ^a   Gabrielli, Fabio ^a   Pregnolato, Massimo ^a,c  

^a Department of Veterinary Medical Sciences   (Switzerland)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d Via dei Faggi 4 ^*  (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; PROTEIN DERIVATIVE; SEROTONIN; TRYPTOPHAN HYDROXYLASE 2; TUBULIN;

ANTHROPOLOGY; CELL MEMBRANE; CYTOSKELETON; DEPRESSION; GENE EXPRESSION; MOLECULAR BIOLOGY; OSTEOPOROSIS; REVIEW; SEROTONIN RELEASE; THROMBOCYTE MEMBRANE; VISCOSITY;

EID: 79953117879     PISSN: None     EISSN: 1744859X     Source Type: Journal    
DOI: 10.1186/1744-859X-10-9     Document Type: Review

References (38)

1. Thompson E, Rosch E. The Embodied Mind. Cognitive Science and Human Experience 1991, Cambridge, MA: MIT Press.
2. Nietzsche F. Untimely meditations, II, on the use and abuse of history for life. 1997, Cambridge, UK: Cambridge University Press.
3. Jankélévítch V. Il non-so-che e il quasi niente 1987, Genova, Italy: Marietti.
4. Gabrielli F. L'uomo a due dimensioni. Anima e corpo, cura e salvezza dall'Orfismo al Platone pre-metafisico 2009, Lugano, Switzerland: Ludes University Press.
5. Leipoldt J, Schenke HM. Koptisch gnostiche Schriften aus dem Papyrus-Codices von Nag Hammadi 1960, Bergstedt, Germany, H. Reich.
6. Lidzbarsky M. Ginza: Des Schatz oder das Grosse Buch der Mandder (Quellen der Religongeschichte, XIII/4). 1925, Göttingen-Leipzig, Germany; Vandenhoeck & Ruprecht.
7. Löwith K. Man between infinities. Measure. A Critical Journal 1950, Chicago, Henry Regnery Company, vol.1.
8. Carotenuto A. Le lacrime del male 2001, Milano, Italy: Bompiani.
9. Cocchi M, Tonello L, Rasenick MM. Human depression: a new approach in quantitative psychiatry. Ann Gen Psychiatry 2010, 9:25. 10.1186/1744-859X-9-25, 2890698, 20525273.
10. Cocchi M, Gabrielli F, Tonello L, Pregnolato M. Interactome hypothesis of depression. Neuroquantology 2010, 8:603-613.
11. Tonello L, Cocchi M. The cell membrane: is it a bridge from psychiatry to quantum consciousness?. Neuroquantology 2010, 8:54-60.
12. Cocchi M, Tonello L. Biomolecular considerations in major depression and ischemic cardiovascular disease. Cent Nerv Syst Agents Med Chem 2010, 10:97-107.
13. Cocchi M, Tonello L, De Lucia A, Amato P. Platelet and brain fatty acids: a model for the classifcation of the animals? Part 1. Int J Anthropology 2009, 24:69-76.
14. Cocchi M, Tonello L, De Lucia A, Amato P. Platelet and brain fatty acids: a model for the classification of the animals? Part 2. Platelet and brain fatty acid transfer: hypothesis on arachidonic acid and its relationship to major depression. Int J Anthropology 2009, 24:69-76.
15. Heron DS, Shinitzky M, Hershkowitz M, Samuel D. Lipid fluidity markedly modulates the binding of serotonin to mouse brain membranes. Proc Natl Acad Sci USA 1980, 77:7463-7467. 10.1073/pnas.77.12.7463, 350524, 6938985.
16. Takahashi S. Reduction of blood platelet serotonin levels in manic and depressed patients. Folia Psychiatr Neurol Jpn 1976, 30:475-486.
17. Stahl SM. The human platelet. A diagnostic and research tool for the study of biogenic amines in psychiatric and neurologic disorders. Arch Gen Psychiatry 1977, 34:509-516.
18. Kim HL, Plaisant O, Leboyer M, Gay C, Kamal L, Devynck MA, Meyer P. Reduction of platelet serotonin in major depression (endogenous depression) [in French]. C R Seances Acad Sci III 1982, 295:619-622.
19. Dreux C, Launay JM. Blood platelets: neuronal model in psychiatric disorders. Encephale 1985, 11:57-64.
20. Ostojic P, Zivojinovic S, Reza T, Milivojevic D, Damjanov N. Symptoms of depression and anxiety in Serbian patients with systemic sclerosis: impact of disease severity and socioeconomic factors. Mod Rheumatol 2010, 20:353-357. 10.1007/s10165-010-0285-7, 20336476.
21. Kurina L, Goldacre M, Yeates D, Gill L. Depression and anxiety in people with inflammatory bowel disease. J Epidemiol Community Health 2001, 55:716-720. 10.1136/jech.55.10.716, 1731788, 11553654.
22. Graff LA, Walker JR, Bernstein CN. Depression and anxiety in inflammatory bowel disease: a review of comorbidity and management. Inflamm Bowel Dis 2009, 15:1105-1118. 10.1002/ibd.20873, 19161177.
23. Horstman LL, Jy W, Ahn YS, Zivadinov R, Maghzi AH, Etemadifar M, Alexander JS, Minagar A. Role of platelets in neuroinflammation: a wide-angle perspective. J Neuroinflammation 2010, 7:10. 10.1186/1742-2094-7-10, 2829540, 20128908.
24. Cocchi M, Tonello L, Lercker G. Fatty acids, membrane viscosity, serotonin and ischemic heart disease. Lipids Health Dis 2010, 9:97. 10.1186/1476-511X-9-97, 2944239, 20825633.
25. Bab IA, Yirmiya R. Depression and bone mass. Ann NY Acad Sci 2010, 1192:170-175. 10.1111/j.1749-6632.2009.05218.x, 20392233.
26. Rosen CJ. Serotonin rising - the bone, brain, bowel connection. N Engl J Med 2009, 360:957-959. 10.1056/NEJMp0810058, 19264685.
27. Yadav VK, Ryu JH, Suda N, Tanaka K, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008, 135:825-837. 10.1016/j.cell.2008.09.059, 2614332, 19041748.
28. Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009, 138:976-989. 10.1016/j.cell.2009.06.051, 2768582, 19737523.
29. Anderson GM, Cook EH, Blakely RD. Serotonin rising. N Engl J Med 2009, 360(24):2580. 10.1056/NEJMc090651, 19516042.
30. de Jong WHA, de Vries EGE, Kema IP. Serotonin rising. N Engl J Med 2009, 360(24):2580-1.
31. Gillis CN. Peripheral metabolism of serotonin. Serotonin and the cardiovascular system 1985, 27-36. New York: Raven Press, Vanhoutte PM.
32. Rosen CJ. Serotonin rising. N Engl J Med 2009, 360(24):2581-2.
33. Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 2005, 434:514-520. 10.1038/nature03398, 15724149.
34. Speth RC. Serotonin rising. N Engl J Med 2009, 360(24):2581.
35. Karsenty G. Regulation of bone mass by serotonin: molecular biology and therapeutic implications. Annu Rev Med 2011, 62:27.1-27.9.
36. Battaglino R, Fu J, Späte U, Ersoy U, Joe M, Sedaghat L, Stashenko P. Serotonin regulates osteoclast differentiation through its transporter. J Bone Mineral Res 2004, 19:1420-1430.
37. Cocchi M, Tonello L, Tsaluchidu S, Puri BK. The use of artificial neural networks to study fatty acids in neuropsychiatric disorders. BMC Psychiatry 2008, 8(Suppl. 1):S3. 10.1186/1471-244X-8-S1-S3, 2330078, 18433513.
38. Axelson DA, Perel JM, Birmaher B, Rudolph G, Nuss S, Yurasits L, Bridge J, Brent DA. Platelet serotonin reuptake inhibition and response to SSRIs in depressed adolescents. Am J Psychiatry 2005, 162:802-804. 10.1176/appi.ajp.162.4.802, 15800159.