Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009

BMC Infectious Diseases

Volumn 11, Issue , 2011, Pages

  Cui, Zhenling ^a   Wang, Jie ^a   Lu, Junmei ^a   Huang, Xiaochen ^a   Hu, Zhongyi ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; GLYCINE; LEUCINE; OFLOXACIN; THREONINE; BACTERIAL DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHINA; CODON; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GYRA GENE; GYRB GENE; MINIMUM INHIBITORY CONCENTRATION; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; STRAIN DIFFERENCE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MUTATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; CHINA; DNA GYRASE; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OFLOXACIN; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUBERCULOSIS;

EID: 79953101714     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-11-78     Document Type: Article

References (32)

1. World Health Organization. Guidelines for the programmatic management of drug resistant tuberculosis WHO/HTM/TB/2006.361. Geneva, Switzerland, World Health Organization. Guidelines for the programmatic management of drug resistant tuberculosis.
2. Ginsburg AS, Grosset JH, Bishai WR. >Fluoroquinolones, tuberculosis, and resistance. Lancet Infect Dis 2003, 3:432-442. 10.1016/S1473-3099(03)00671-6, 12837348.
3. Jérémie P, Stéphanie P, Marc D, Gwénaëlle A, Vincent J, Alexandra A, Claudine M. Structural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA Gyrase. PLoS One 2010, 5:e12245. 2923608, 20805881.
4. Alexandra A, Nicolas V, Emmanuelle C, Chantal T, Vincent J, Mark Fisher L. Novel Gyrase Mutations in Quinolone-Resistant and -Hypersusceptible Clinical Isolates of Mycobacterium tuberculosis: Functional Analysis of Mutant Enzymes. Antimicrob Agents Chemother 2006, 50:104-112. 10.1128/AAC.50.1.104-112.2006, 1346799, 16377674.
5. Poissy J, Aubry A, Fernandez C, Lott MC, Chauffour A, Jarlier V, Farinotti R, Veziris N. Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? An answer from a murine model. Antimicrob Agents Chemother 2010, 54:4765-71. 10.1128/AAC.00968-10, 20805388.
6. Wang JY, Lee LN, Lai HC, Wang SK, Jan IS, Yu CJ, Hsueh PR, Yang PC. Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimicrobial exposure. J Antimicrob Chemother 2007, 59:860-865. 10.1093/jac/dkm061, 17412727.
7. WHO The WHO/IUATLD Global Project on Anti-tuberculosis Drug Resistance Surveillance. Anti-tuberculosis drug resistance in the world (Report No.4). WHO/HTM/TB/2008.394. Geneva, Switzerland, WHO.
8. World Health Organization Report of the second meeting of the WHO Task Force on XDR-TB. WHO/HTM/TB/2008.403. Geneva, Switzerland, World Health Organization.
9. Zhao M, Li X, Xu P, Shen X, Gui X, Wang L, Deriemer K, Mei J, Gao Q. Transmission of MDR and XDR tuberculosis in Shanghai. China PLoS One 2009, 4:e4370.
10. Mokrousov I, Otten T, Manicheva O, Potapova Y, Vishnevsky B, Narvskaya O, Rastogi N. Molecular characterization of ofloxacin-resistant Mycobacterium tuberculosis strains from Russia. Antimicrob Agents Chemother 2008, 52:2937-2939. 10.1128/AAC.00036-08, 2493099, 18559646.
11. Shi R, Zhang J, Li C, Kazumi Y, Sugawara I. Emergence of ofloxacin resistance in Mycobacterium tuberculosis clinical isolates from China as determined by gyrA mutation analysis using denaturing high-pressure liquid chromatography and DNA sequencing. J Clin Microbiol 2006, 44:4566-4568. 10.1128/JCM.01916-06, 1698392, 17035499.
12. Van Doorn HR, An DD, de Jong MD, Lan NT, Hoa DV, Quy HT, Chau NV, Duy PM, Tho DQ, Chinh NT, Farrar JJ, Caws M. Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR. Int J Tuberc Lung Dis 2008, 12:736-742.
13. Yin X, Yu Z. Mutation characterization of gyrA and gyrB genes in levofloxacin-resistant Mycobacterium tuberculosis clinical isolates from Guangdong Province in China. J Infect 2010, 61:150-154. 10.1016/j.jinf.2010.05.001, 20452372.
14. Zhao MC, Bao L, Wu YH, Long Y, Zeng XW, Zhang HD, Xie YX. Study on the gene mutation of quinolone resistant Mycobacterium tuberculosis isolated from Sichuan Province. Sichuan Da Xue Xue Bao Yi Xue Ban 2004, 35:313-315.
15. Brossier F, Veziris N, Aubry A, Jarlier V, Sougakoff W. Detection by GenoType MTBDRsl test of complex mechanisms of resistance to secondline drugs and ethambutol in multidrug resistant Mycobacterium tuberculosis complex isolates. J Clin Microbiol 2010, 48:1683-1689. 10.1128/JCM.01947-09, 2863904, 20335420.
16. Duong DA, Nguyen TH, Nguyen TN, Dai VH, Dang TM, Vo SK, Do DA, Nguyen VV, Nguyen HD, Dinh NS, Farrar J, Caws M. Beijing genotype of Mycobacterium tuberculosis is significantly associated with high-level fluoroquinolone resistance in Vietnam. Antimicrob Agents Chemother 2009, 53:4835-4839. 10.1128/AAC.00541-09, 2772334, 19721073.
17. Feuerriegel S, Cox HS, Zarkua N, Karimovich HA, Braker K, Rüsch-Gerdes S, Niemann S. Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment. Antimicrob Agents Chemother 2009, 53:3353-3356. 10.1128/AAC.00050-09, 2715645, 19470506.
18. Evans J, Segal H. Novel multiplex allele-specific PCR assays for the detection of resistance to second-line drugs in Mycobacterium tuberculosis. J Antimicrob Chemother 2010, 65:897-900. 10.1093/jac/dkq047, 20185419.
19. Guillemin I, Jarlier V, Cambau E. Correlation between quinolone susceptibility patterns and sequences in the A and B subunits of DNA gyrase in mycobacteria. Antimicrob Agents Chemother 1998, 42:2084-2088. 105866, 9687411.
20. Van Embden JD, Cave MD, Crawford JT, Dale JW, Eisenach KD, Gicquel B, Hermans P, Martin C, McAdam R, Shinnick TM, SMALL PM. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol 1993, 31:406-409. 262774, 8381814.
21. Benjamin WH, Lok KH, Harris R, Brook N, Bond L, Mulcahy D, Robinson N, Pruitt V, Kirkpatrick DP, Kimerling ME, Dunlap NE. Identification of a contaminating Mycobacterium tuberculosis strain with a transposition of an IS6110 insertion element resulting in an altered spoligotype. J Clin Microbiol 2001, 39:1092-1096. 10.1128/JCM.37.3.1092-1096.2001, 87878, 11230432.
22. Bemer P, Palicova F, Rüsch-Gerdes S, Drugeon HB, Pfyffer GE. Multicenter evaluation of fully automated BACTEC Mycobacteria Growth Indicator Tube 960 system for susceptibility testing of Mycobacterium tuberculosis. J Clin Microbiol 2002, 40:150-154. 10.1128/JCM.40.1.150-154.2002, 120114, 11773109.
23. Rüsch-Gerdes S, Pfyffer GE, Casal M, Chadwick M, Siddiqi S. Multicenter laboratory validation of the BACTEC MGIT 960 technique for testing susceptibilities of Mycobacterium tuberculosis to classical second-line drugs and newer antimicrobials. J Clin Microbiol 2006, 44:688-692. 1393114, 16517840.
24. Kumar M, Khan IA, Verma V, Kalyan N, Qazi GN. Rapid, inexpensive MIC determination of Mycobacterium tuberculosis isolates by using microplate nitrate reductase assay. Diagn Microbiol Infect Dis 2005, 53:121-124. 10.1016/j.diagmicrobio.2005.05.011, 16168616.
25. Sreevatsan S, Pan X, Stockbauer KE, Connell ND, Kreiswirth BN, Whittam TS, Musser JM. Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sci USA 1997, 94:9869-9874. 10.1073/pnas.94.18.9869, 23284, 9275218.
26. Huitric E, Werngren J, Juréen P, et al. Resistance levels and rpoB gene mutations among in vitro-selected rifampin-resistant Mycobacterium tuberculosis mutants. Antimicrob Agents Chemother 2006, 50:2860-2862. 10.1128/AAC.00303-06, 1538691, 16870787.
27. Kim SY, Park YJ, Kim WI, et al. Molecular analysis of isoniazid resistance in Mycobacterium tuberculosis isolates recovered from South Korea. Diagn Microbiol Infect Dis 2003, 47:497-502. 10.1016/S0732-8893(03)00132-9, 14596968.
28. Takiff HE, Salazar Takiff HE, Salazar L, Guerrero C, Philipp W, Huang WM, Kreiswirth B, Cole ST, Jacobs WR, Telenti A. Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations. Antimicrob Agents Chemother 1994, 38:773-780. 284541, 8031045.
29. Sun Z, Zhang J, Zhang X, Wang S, Zhang Y, Li C. Comparison of gyrA gene mutations between laboratory-selected ofloxacin-resistant Mycobacterium tuberculosis strains and clinical isolates. Int J Antimicrob Agents 2008, 31:115-121. 10.1016/j.ijantimicag.2007.10.014, 18164184.
30. Comas I, Homolka S, Niemann S, Gagneux S. Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies. PLoS One 2009, 4:e7815. 10.1371/journal.pone.0007815, 2772813, 19915672.
31. Pitaksajjakul P, Wongwit W, Punprasit W, Eampokalap B, Peacock S, Ramasoota P. Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. Mutations in the gyrA and gyrB genes of fluoroquinolone-resistant Mycobacterium tuberculosis from TB patients in Thailand. Southeast Asian J Trop Med Public Health 2005, 36:228-237.
32. Von Groll A, Martin A, Jureen P, Hoffner S, Vandamme P, Portaels F, Palomino JC, da Silva PA. Fluoroquinolone resistance in Mycobacterium tuberculosis and mutations in gyrA and gyrB. Antimicrob Agents Chemother 2009, 53:4498-4500. 10.1128/AAC.00287-09, 2764174, 19687244.