Development of an orthogonal method for mometasone furoate impurity analysis using supercritical fluid chromatography

Journal of Chromatography A

Volumn 1218, Issue 16, 2011, Pages 2311-2319

  Wang, Zhenyu ^a   Zhang, Honggen ^a   Liu, Oscar ^a   Donovan, Brent ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Impurity analysis; Method validation; Mometasone furoate; Orthogonal selectivity; Sensitivity improvement; Supercritical fluid chromatography

Indexed keywords

METHOD VALIDATIONS; MOMETASONE FUROATE; ORTHOGONAL SELECTIVITY; SENSITIVITY IMPROVEMENT; SUPERCRITICAL FLUID CHROMATOGRAPHY;

CHIRALITY; DRUG PRODUCTS; EFFLUENT TREATMENT; GAS CHROMATOGRAPHY; IMPURITIES; METHANOL; SILICA; SUPERCRITICAL FLUIDS;

TRACE ANALYSIS;

CARBON DIOXIDE; FORMOTEROL FUMARATE PLUS MOMETASONE FUMARATE; METHANOL; MOMETASONE FUROATE;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG IMPURITY; DRUG STRUCTURE; LIMIT OF QUANTITATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SUPERCRITICAL FLUID CHROMATOGRAPHY;

CARBON DIOXIDE; CHROMATOGRAPHY, SUPERCRITICAL FLUID; DRUG CONTAMINATION; METHANOL; PREGNADIENEDIOLS; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 79953069856     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.02.027     Document Type: Article

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