Micronization of fluticasone propionate using supercritical antisolvent (SAS) process

Chemical Engineering and Technology

Volumn 34, Issue 4, 2011, Pages 535-541

  Su, C S ^a   Lo, W S ^a   Lien, L H ^a  

^a ScinoPharm Taiwan Ltd   (Taiwan)

Author keywords

Fluticasone propionate; Micronization; Mixture critical point; Supercritical antisolvent

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; ANTI-SOLVENTS; CROSS INTERACTIONS; FLUTICASONE PROPIONATE; MEAN SIZE; MICRO-PARTICLES; MICRONIZATION; MICRONIZATIONS; MIXTURE CRITICAL POINT; NOZZLE DIAMETER; OPERATING PRESSURE; OPERATING TEMPERATURE; PARTICLE SIZE ANALYZERS; PREDICTIVE SOAVE-REDLICH-KWONG; PROCESS PARAMETERS; PULMONARY DRUG DELIVERY; SCANNING ELECTRON MICROSCOPE; SOLUTION CONCENTRATION; SOLUTION FLOW RATE; SUPERCRITICAL ANTISOLVENT; SUPERCRITICAL ANTISOLVENT PROCESS; SUPERCRITICAL CARBON DIOXIDES; X RAY DIFFRACTOMETERS;

BINARY MIXTURES; CARBON DIOXIDE; DRUG DELIVERY; DRUG PRODUCTS; EQUATIONS OF STATE; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; PRESSURE EFFECTS; SCANNING ELECTRON MICROSCOPY; TEMPERATURE; VOLATILE FATTY ACIDS;

SUPERCRITICAL FLUID EXTRACTION;

EID: 79953057083     PISSN: 09307516     EISSN: 15214125     Source Type: Journal    
DOI: 10.1002/ceat.201000462     Document Type: Article

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