Processing of facial expressions and their significance for the observer in subregions of the human amygdala

NeuroImage

Volumn 56, Issue 1, 2011, Pages 299-306

  Boll, Sabrina ^a   Gamer, Matthias ^a   Kalisch, Raffael ^a   Büchel, Christian ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Amygdala; Anger; Context; Facial expressions; Fear; High resolution fMRI

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ANGER; ARTICLE; ASSOCIATION; BASAL AMYGDALA; BRAIN REGION; CONTROLLED STUDY; EMOTION; FACIAL EXPRESSION; FEAR; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GAZE; HUMAN; HUMAN EXPERIMENT; INFORMATION PROCESSING; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SIGNAL PROCESSING; VOLUNTEER;

ADULT; AMYGDALA; BRAIN MAPPING; EMOTIONS; FACIAL EXPRESSION; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; PATTERN RECOGNITION, VISUAL; YOUNG ADULT;

EID: 79953052381     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2011.02.021     Document Type: Article

References (47)

1. Adams R.B., Kleck R.E. Perceived gaze direction and the processing of facial displays of emotion. Psychol. Sci. 2003, 14:644-647.
2. Adams R.B., Kleck R.E. Effects of direct and averted gaze on the perception of facially communicated emotion. Emotion 2005, 5:3-11.
3. Adolphs R. The neurobiology of social cognition. Curr. Opin. Neurobiol. 2001, 11:231-239.
4. Adolphs R. Fear, faces, and the human amygdala. Curr. Opin. Neurobiol. 2008, 18:166-172.
5. Adolphs R., Spezio M. Role of the amygdala in processing visual social stimuli. Prog. Brain Res. 2006, 156:363-378.
6. Akiyama T., Kato M., Muramatsu T., Umeda S., Saito F., Kashima H. Unilateral amygdala lesions hamper attentional orienting triggered by gaze direction. Cereb. Cortex 2007, 17:2593-2600.
7. Amaral D.G., Price J.L., Pitkanen A., Carmichael S.T. Anatomical organization of the primate amygdaloid complex. The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction 1992, 1-66. Wiley-Liss, New York. J.P. Aggelton (Ed.).
8. Ando S. Luminance-induced shift in the apparent direction of gaze. Perception 2002, 31:657-674.
9. Ando S. Perception of gaze direction based on luminance ratio. Perception 2004, 33:1173-1184.
10. Calder A.J., Young A.W. Understanding the recognition of facial identity and facial expression. Nat. Rev. Neurosci. 2005, 6:641-651.
11. Canli T., Lesch K.P. Long story short: the serotonin transporter in emotion regulation and social cognition. Nat. Neurosci. 2007, 10:1103-1109.
12. Chow T.W., Cummings J.L. The amygdala and Alzheimer's disease. The Amygdala: A Functional Analysis 2000, 655-680. Oxford University Press, Oxford, UK. 2nd Edition. J.P. Aggelton (Ed.).
13. Cristinzio C., N'Diaye K., Seeck M., Vuilleumier P., Sander D. Integration of gaze direction and facial expression in patients with unilateral amygdala damage. Brain 2010, 133:248-261.
14. Davis F.C., Johnstone T., Mazzulla E.C., Oler J.A., Whalen P.J. Regional response differences across the human amygdaloid complex during social conditioning. Cereb. Cortex 2010, 20(3):612-621.
15. Filipp S.H., Freudenberg E. Fragebogen zur Erfassung dispositionaler Selbstaufmerksamkeit 1989, Hogrefe, Göttingen.
16. Fitzgerald D.A., Angstadt M., Jelsone L.M., Nathan P.J., Phan K.L. Beyond threat: amygdala reactivity across multiple expressions of facial affect. Neuroimage 2006, 30:1441-1448.
17. Gamer M., Buchel C. Amygdala activation predicts gaze toward fearful eyes. J. Neurosci. 2009, 29:9123-9126.
18. Gamer M., Zurowski B., Buchel C. Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans. Proc. Natl Acad. Sci. USA 2010, 107:9400-9405.
19. Goeleven E., De Raedt R., Leyman L., Verschuere B. The Karolinska directed emotional faces: a validation study. Cogn. Emotion 2008, 22:1094-1118.
20. Gothard K.M., Battaglia F.P., Erickson C.A., Spitler K.M., Amaral D.G. Neural responses to facial expression and face identity in the monkey amygdala. J. Neurophysiol. 2007, 97:1671-1683.
21. Hadjikhani N., Hoge R., Snyder J., de Gelder B. Pointing with the eyes: the role of gaze in communicating danger. Brain Cogn. 2008, 68:1-8.
22. Hariri A.R., Mattay V.S., Tessitore A., Kolachana B., Fera F., Goldman D., Egan M.F., Weinberger D.R. Serotonin transporter genetic variation and the response of the human amygdala. Science 2002, 297:400-403.
23. Haxby J.V., Hoffman E.A., Gobbini M.I. Human neural systems for face recognition and social communication. Biol. Psychiatry 2002, 51:59-67.
24. Heinz A., Braus D.F., Smolka M.N., Wrase J., Puls I., Hermann D., Klein S., Grusser S.M., Flor H., Schumann G., Mann K., Buchel C. Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter. Nat. Neurosci. 2005, 8:20-21.
25. Heubrock D., Petermann F. Kurzfragebogen zur Erfassung von Aggressivitätsfaktoren 2008, Hogrefe, Göttingen.
26. Hoffman K.L., Gothard K.M., Schmid M.C., Logothetis N.K. Facial-expression and gaze-selective responses in the monkey amygdala. Curr. Biol. 2007, 17:766-772.
27. Kuraoka K., Nakamura K. Responses of single neurons in monkey amygdala to facial and vocal emotions. J. Neurophysiol. 2007, 97:1379-1387.
28. Laux L., Glanzmann P., Schaffner P., Spielberger C.D. Das State-Trait-Angstinventar 1981, Weinheim, Beltz.
29. LeDoux J. The amygdala. Curr. Biol. 2007, 17:R868-R874.
30. Leonard C.M., Rolls E.T., Wilson F.A., Baylis G.C. Neurons in the amygdala of the monkey with responses selective for faces. Behav. Brain Res. 1985, 15:159-176.
31. Lundqvist D., Flykt A., Öhman A. The Karolinska directed emotional faces - KDEF. CD-ROM from Department of Clinical Neuroscience, Psychology section, Karolinska Institute 1998.
32. Mai J.K., Assheuer J., Paxinos G. Atlas of the Human Brain 1997, Academic Press, San Diego.
33. N'Diaye K., Sander D., Vuilleumier P. Self-relevance processing in the human amygdala: gaze direction, facial expression, and emotion intensity. Emotion 2009, 9:798-806.
34. Phillips M.L., Williams L., Senior C., Bullmore E.T., Brammer M.J., Andrew C., Williams S.C., David A.S. A differential neural response to threatening and non-threatening negative facial expressions in paranoid and non-paranoid schizophrenics. Psychiatry Res. 1999, 92:11-31.
35. Pichon S., de Gelder B., Grezes J. Two different faces of threat. Comparing the neural systems for recognizing fear and anger in dynamic body expressions. Neuroimage 2009, 47:1873-1883.
36. Pitkänen A. Connectivity of the rat amygdaloid complex. The Amygdala: A Functional Analysis 2000, 31-115. Oxford University Press, Oxford, UK. 2nd Edition. J.P. Aggelton (Ed.).
37. Sah P., Faber E.S., Lopez De Armentia M., Power J. The amygdaloid complex: anatomy and physiology. Physiol. Rev. 2003, 83:803-834.
38. Sander D., Grafman J., Zalla T. The human amygdala: an evolved system for relevance detection. Rev. Neurosci. 2003, 14:303-316.
39. Sander D., Grandjean D., Kaiser S., Wehrle T., Scherer K.R. Interaction effects of perceived gaze direction and dynamic facial expression: evidence for appraisal theories of emotion. Eur. J. Cogn. Psychol. 2007, 19:470-480.
40. Sato W., Yoshikawa S., Kochiyama T., Matsumura M. The amygdala processes the emotional significance of facial expressions: an fMRI investigation using the interaction between expression and face direction. Neuroimage 2004, 22:1006-1013.
41. Schumann C.M., Amaral D.G. Stereological analysis of amygdala neuron number in autism. J. Neurosci. 2006, 26:7674-7679.
42. Schwenkmezger P., Hodapp V., Spielberger C.D. Das State-Trait-Argerausdrucksinventar STAXI 1992, Huber, Bern.
43. Smith S.M., Jenkinson M., Woolrich M.W., Beckmann C.F., Behrens T.E., Johansen-Berg H., Bannister P.R., De Luca M., Drobnjak I., Flitney D.E., Niazy R.K., Saunders J., Vickers J., Zhang Y., De Stefano N., Brady J.M., Matthews P.M. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004, 23(Suppl. 1):S208-S219.
44. Spezio M.L., Huang P.Y., Castelli F., Adolphs R. Amygdala damage impairs eye contact during conversations with real people. J. Neurosci. 2007, 27:3994-3997.
45. Spielberger C.D., Gorsuch R.L., Lushene R.E. STAI manual for the State-Trait-Anxiety Inventory 1970, Consulting Psychologist, Palo Alto, CA.
46. Straube T., Langohr B., Schmidt S., Mentzel H.J., Miltner W.H. Increased amygdala activation to averted versus direct gaze in humans is independent of valence of facial expression. Neuroimage 2010, 49(3):2680-2686.
47. Whalen P.J., Shin L.M., McInerney S.C., Fischer H., Wright C.I., Rauch S.L. A functional MRI study of human amygdala responses to facial expressions of fear versus anger. Emotion 2001, 1:70-83.