On the missing link between inflammation and cancer

Dermatology Online Journal

Volumn 17, Issue 1, 2011, Pages

  Alexandrescu, Doru T ^a,b   Riordan, Neil H ^c   Ichim, Thomas E ^c   Lisa Kauffman, C ^a   Kabigting, Filamer ^b   Dutton, Constance T ^e   Dasanu, Constantin A ^d  

^a Georgetown Dermatology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Medistem Inc   (United States)

^d SAINT FRANCIS HOSPITAL AND MEDICAL CENTER   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GROWTH FACTOR;

ACUTE FEBRILE NEUTROPHILIC DERMATOSIS; ANGIOGENESIS; ARTICLE; DISEASE ASSOCIATION; EPIGENETICS; GRANULOMA ANNULARE; HUMAN; IMMUNOPATHOLOGY; INFLAMMATION; MALIGNANT NEOPLASTIC DISEASE; PSORIASIS; PYODERMA GANGRENOSUM; SARCOIDOSIS; SUBCORNEAL PUSTULAR DERMATOSIS; GRANULOMA; NEOPLASM; NOTE; PARANEOPLASTIC SYNDROME; PATHOPHYSIOLOGY; SKIN DISEASE;

GRANULOMA; HUMANS; INFLAMMATION; NEOPLASMS; PARANEOPLASTIC SYNDROMES; SARCOIDOSIS; SKIN DISEASES;

EID: 79953040147     PISSN: 10872108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Cohen PR. Granuloma annulare, relapsing polychondritis, sarcoidosis, and systemic lupus erythematosus: conditions whose dermatologic manifestations may occur as hematologic malignancy-associated mucocutaneous paraneoplastic syndromes. Int J Dermatol. 2006;45:70-80. [PubMed]
2. Cohen PR. Neutrophilic dermatoses: a review of current treatment options. Am J Clin Dermatol. 2009;10:301-12. [PubMed]
3. Weenig RH, Bruce AJ, McEvoy MT, Gibson LE, Davis MD. Neutrophilic dermatosis of the hands: four new cases and review of the literature. Int J Dermatol. 2004;43:95-102. [PubMed]
4. Dannenberg AJ, Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. Cancer Cell. 2003;4:431-6. [PubMed]
5. Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol. 2009;182:4499-506. [PubMed]
6. Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature. 2008;454:436-44. [PubMed]
7. Berasain C, Castillo J, Perugorria MJ, Latasa MU, Prieto J, Avila MA. Inflammation and liver cancer: new molecular links. Ann N Y Acad Sci. 2009;1155:206-21. [PubMed]
8. Mathew S, Bauer KL, Fischoeder A, Bhardwaj N, Oliver SJ. The anergic state in sarcoidosis is associated with diminished dendritic cell function. J Immunol. 2008;181:746-55. [PubMed]
9. Sahashi K, Ina Y, Takada K, Sato T, Yamamoto M, Morishita M. Significance of interleukin 6 in patients with sarcoidosis. Chest. 1994;106:156-60. [PubMed]
10. Brincker H. Sarcoidosis and malignancy. Chest. 1995;108:1472-4. [PubMed]
11. Valentonyte R, Hampe J, Huse K, Rosenstiel P, Albrecht M, Stenzel A, Nagy M, Gaede KI, Franke A, Haesler R, Koch A, Lengauer T, Seegert D, Reiling N, Ehlers S, Schwinger E, Platzer M, Krawczak M, Müller-Quernheim J, Schürmann M, Schreiber S. Sarcoidosis is associated with a truncating splice site mutation in BTNL2. Nat Genet. 2005;37:357-64. [PubMed]
12. Ota M, Amakawa R, Uehira K, Ito T, Yagi Y, Oshiro A, Date Y, Oyaizu H, Shigeki T, Ozaki Y, Yamaguchi K, Uemura Y, Yonezu S, Fukuhara S. Involvement of dendritic cells in sarcoidosis. Thorax. 2004;59:408-13. [PubMed]
13. Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, Trad S, Kambouchner M, Valeyre D, Chapelon-Abric C, Debré P, Piette JC, Gorochov G. The immune paradox of sarcoidosis and regulatory T cells. J Exp Med. 2006;203:359-70. [PubMed]
14. Taflin C, Miyara M, Nochy D, Valeyre D, Naccache JM, Altare F, Salek-Peyron P, Badoual C, Bruneval P, Haroche J, Mathian A, Amoura Z, Hill G, Gorochov G. FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions. Am J Pathol. 2009;174:497-508. [PubMed]
15. Beyer M, Schultze JL. Immunoregulatory T cells: role and potential as a target in malignancy. Curr Oncol Rep. 2008;10:130-6.
16. Hviid TV, Milman N, Hylenius S, Jakobsen K, Jensen MS, Larsen LG. HLA-G polymorphisms and HLA-G expression in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2006;23:30-7. [PubMed]
17. Papadopoulos KI, Hörnblad Y, Liljebladh H, Hallengren B. High frequency of endocrine autoimmunity in patients with sarcoidosis. Eur J Endocrinol. 1996;134:331-6. [PubMed]
18. Landgren O, Engels EA, Pfeiffer RM, Gridley G, Mellemkjaer L, Olsen JH, Kerstann KF, Wheeler W, Hemminki K, Linet MS, Goldin LR. Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia. J Natl Cancer Inst. 2006;98:1321-30. [PubMed]
19. Baniyash M. TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response. Nat Rev Immunol. 2004;4:675-87. [PubMed]
20. Shigehara K, Shijubo N, Nakanishi F, Hirasawa M, Inuzuka M, Ohmichi M, Hiraga Y, Abe S. Circulating gamma delta-T-cell-receptor-positive lymphocytes in sarcoidosis. Respiration. 1995;62:84-8. [PubMed]
21. Balbi B, Valle MT, Oddera S, Giunti D, Manca F, Rossi GA, Allegra L. T-lymphocytes with gamma delta+ V delta 2+ antigen receptors are present in increased proportions in a fraction of patients with tuberculosis or with sarcoidosis. Am Rev Respir Dis. 1993;148:1685-90. [PubMed]
22. Granel B, Camoin L, Serratrice J, et al. Retrospective study of 55 patients with circulating blood T gama/delta lymphocytosis. Rev Med Interne. 2002;23:137-43. [PubMed]
23. Nakata K, Sugie T, Cohen H, Nakano H, Aoki M. Expansion of circulating gamma delta T cells in active sarcoidosis closely correlates with defects in cellular immunity. Clin Immunol Immunopathol. 1995;74:217-22. [PubMed]
24. Nakata K, Sugie T, Nakano H, Sakai T, Aoki M. Gamma-delta T cells in sarcoidosis. Correlation with clinical features. Am J Respir Crit Care Med. 1994;149:981-8. [PubMed]
25. Vilmer E, Guglielmi P, David V, Leca G, Rabian C, Degos L, Boiron M, Bensussan A. Predominant expression of circulating CD3+ lymphocytes bearing gamma T cell receptor in a prolonged immunodeficiency after allogeneic bone marrow transplantation. J Clin Invest. 1988;82:755-61. [PubMed]
26. Fujita M, Miyachi Y, Nakata K, Imamura S. Gamma delta T-cell receptor-positive cells in human skin. I. Incidence and V-region gene expression in granulomatous skin lesions. J Am Acad Dermatol. 1993 Jan;28(1):46-50. PubMed [PubMed]
27. Wilsher ML, Hallowes M, Birchall NM. Gamma/delta cells in tissue from patients with sarcoidosis. Thorax. 1996;51:1123-6. [PubMed]
28. Hirokawa M, Horiuchi T, Kawabata Y, Kitabayashi A, Miura AB. Reconstitution of gammadelta T cell repertoire diversity after human allogeneic hematopoietic cell transplantation and the role of peripheral expansion of mature T cell population in the graft. Bone Marrow Transplant. 2000;26:177-85. [PubMed]
29. Munro CS, Campbell DA, Du Bois RM, Mitchell DN, Cole PJ, Poulter LW. Dendritic cells in cutaneous, lymph node and pulmonary lesions of sarcoidosis. Scand J Immunol. 1987;25:461-7. [PubMed]
30. Gerke AK, Hunninghake G. The immunology of sarcoidosis. Clin Chest Med. 2008;29:379-90, vii. [PubMed]
31. Salmeri FM, Sofo V, Andò FG, Vastola MB, Crosca S, Bitto A, Gaeta M, Girbino G. Imbalance of serum cytokine network in sarcoid patients: index of sarcoidosis relapse? Sarcoidosis Vasc Diffuse Lung Dis. 2003;20:53-61. [PubMed]
32. Kleine-Lowinski K, Gillitzer R, Kühne-Heid R, Rösl F. Monocyte-chemo-attractant-protein-1 (MCP-1)-gene expression in cervical intra-epithelial neoplasias and cervical carcinomas. Int J Cancer. 1999 Jul 2;82(1):6-11. [PubMed]
33. Bach JP, Deuster O, Balzer-Geldsetzer M, Meyer B, Dodel R, Bacher M. The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors. Cancer. 2009;115:2031-40. [PubMed]
34. Fischer M, Harvima IT, Carvalho RF, Möller C, Naukkarinen A, Enblad G, Nilsson G. Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion. J Clin Invest. 2006;116:2748-56. [PubMed
35. Kollmar O, Scheuer C, Menger MD, Schilling MK. Macrophage inflammatory protein-2 promotes angiogenesis, cell migration, and tumor growth in hepatic metastasis. Ann Surg Oncol. 2006;13:263-75. [PubMed
36. Baughman RP, Strohofer SA, Buchsbaum J, Lower EE. Release of tumor necrosis factor by alveolar macrophages of patients with sarcoidosis. J Lab Clin Med. 1990;115:36-42. [PubMed]
37. Theilmann L, Meyer U, Kommerell B, Dierkesmann R, Möller A. Alpha tumor necrosis factor in the serum of patients with sarcoidosis, tuberculosis or bronchial cancer. Pneumologie. 1990 Apr;44(4):735-8. [PubMed]
38. Seitzer U, Swider C, Stüber F, Suchnicki K, Lange A, Richter E, Zabel P, Müller-Quernheim J, Flad HD, Gerdes J. Tumour necrosis factor alpha promoter gene polymorphism in sarcoidosis. Cytokine. 1997;9:787-90. [PubMed]
39. Agostini C, Basso U, Semenzato G. Cells and molecules involved in the development of sarcoid granuloma. J Clin Immunol. 1998 May;18(3):184-92. Review. PubMed [PubMed]
40. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow?. Lancet. 2001;357:539-45. [PubMed]
41. Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009;9:361-71. [PubMed]
42. Yokoyama T, Kanda T, Kobayashi I, Suzuki T. Serum levels of interleukin-8 as a marker of disease activity in patients with chronic sarcoidosis. J Med. 1995;26:209-19.
43. Kobayashi H, Lin PC. Angiogenesis links chronic inflammation with cancer. Methods Mol Biol. 2009;511:185-91. [PubMed]
44. Yang GY, Taboada S, Liao J. Induced nitric oxide synthase as a major player in the oncogenic transformation of inflamed tissue. Methods Mol Biol. 2009;512:119-56. [PubMed]
45. Zielonka TM, Demkow U, Puscinska E, Golian-Geremek A, Filewska M, Zycinska K, Białas-Chromiec B, Wardyn KA, Skopińska-Rózewska E. TNFalpha and INFgamma inducing capacity of sera from patients with interstitial lung disease in relation to its angiogenesis activity. J Physiol Pharmacol. 2007;58 Suppl 5:767-80. [PubMed]
46. Sekiya M, Ohwada A, Miura K, Takahashi S, Fukuchi Y. Serum vascular endothelial growth factor as a possible prognostic indicator in sarcoidosis. Lung. 2003;181(5):259-65. [PubMed]
47. Suga M, Iyonaga K, Ichiyasu H, Saita N, Yamasaki H, Ando M. Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseases. Eur Respir J. 1999 Aug;14(2):376-82. [PubMed]
48. Brigelius-Flohé R, Kipp A. Glutathione peroxidases in different stages of carcinogenesis. Biochim Biophys Acta. 2009 Mar 13. [Epub ahead of print] [PubMed]
49. Cerutti PA. Prooxidant states and tumor promotion. Science. 1985;227:375-81. [PubMed]
50. Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell. 2008;13:23-35. [PubMed]
51. Blander JM. Analysis of the TLR/NF-kappaB Pathway in Antigen-Presenting Cells in Malignancies Promoted by Inflammation. Methods Mol Biol. 2009;512:99-117. [PubMed]
52. Drent M, van den Berg R, Haenen GR, van den Berg H, Wouters EF, Bast A. NF-kappaB activation in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2001;18:50-6. [PubMed]