Protection of human muscle acetylcholinesterase from soman by pyridostigmine bromide

Muscle and Nerve

Volumn 43, Issue 4, 2011, Pages 591-595

  Maselli, Ricardo A ^a   Henderson, John D ^b   Ng, Jarae ^a   Follette, David ^c   Graves, Gregory ^d   Wilson, Barry W ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Mercy General Hospital   (United States)

^d Sutter General Hospital   (United States)

Author keywords

AChE; Human muscle; MEPPs; Pyridostigmine bromide; Soman

Indexed keywords

ACETYLCHOLINESTERASE; PYRIDOSTIGMINE; SOMAN; CHOLINESTERASE INHIBITOR; PROTECTIVE AGENT;

ARTICLE; BIOCHEMICAL COMPOSITION; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HUMAN; HUMAN TISSUE; INTERCOSTAL MUSCLE; MEMBRANE STEADY POTENTIAL; MINIATURE ENDPLATE POTENTIAL; MUSCLE CELL; PRIORITY JOURNAL; PROTECTION; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; ORGAN CULTURE TECHNIQUE; TOXICITY;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERCOSTAL MUSCLES; ORGAN CULTURE TECHNIQUES; PROTECTIVE AGENTS; PYRIDOSTIGMINE BROMIDE; SOMAN;

EID: 79953036473     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.21922     Document Type: Article

References (20)

1. Schmaltz F. Neurosciences and research on chemical weapons of mass destruction in Nazi Germany. J Hist Neurosci 2006;15:186-209. (Pubitemid 44181247)
2. Marrs TC, Rice P, Vale JA. The role of oximes in the treatment of nerve agent poisoning in civilian casualties. Toxicol Rev 2006;25:297-323.
3. Maselli RA, Soliven BC. Analysis of the organophosphate-induced electromyographic response to repetitive nerve stimulation: paradoxical response to edrophonium and D-tubocurarine. Muscle Nerve 1991;14:1182-1188.
4. Sidell FR. Clinical effects of organophosphorus cholinesterase inhibitors. J Appl Toxicol 1994;14:111-113. (Pubitemid 24124987)
5. Worek F, Thiermann H, Szinicz L. Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines. Arch Toxicol 2004;78:212-217. (Pubitemid 38651055)
6. Casida JE, Quistad GB. Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets. Chem Res Toxicol 2004;17:983-998. (Pubitemid 39108669)
7. Li H, Schopfer LM, Nachon F, Froment MT, Masson P, Lockridge O. Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry. Toxicol Sci 2007;100:136-145. (Pubitemid 47617811)
8. Gordon JJ, Leadbeater L, Maidment MP. The protection of animals against organophosphate poisoning by pretreatment with a carbamate. Toxicol Appl Pharmacol 1978;43:207-216. (Pubitemid 8274260)
9. Layish I, Krivoy A, Rotman E, Finkelstein A, Tashma Z, Yehezkelli Y. Pharmacologic prophylaxis against nerve agent poisoning. Isr Med Assoc J 2005;7:182-187. (Pubitemid 40424965)
10. Tuovinen K, Kaliste-Korhonen E, Raushel FM, Hanninen O. Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication. Toxicology 1999;134:169-178. (Pubitemid 29248889)
11. Haigh JR, Adler M, Apland JP, Deshpande SS, Barham CB, Desmond P, et al. Protection by pyridostigmine bromide of marmoset hemi-diaphragm acetylcholinesterase activity after soman exposure. Chem Biol Interact 2010;187:416-420.
12. Burton A. Take your pyridostigmine: that's an (ethical?) order! Lancet Neurol 2003;2:268.
13. Stern LZ, Gruener R, Anderson RM. External intercostal muscle biopsy. Arch Neurol 1975;32:779-780.
14. Newsom-Davis J. Lambert-Eaton myasthenic syndrome. Rev Neurol 2004;160:177-180. (Pubitemid 38325734)
15. Ellman GL, Courtney KD, Andres V Jr, Feather-Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88-95.
16. Wilson BW, Henderson JD. Determination of cholinesterase in blood and tissue. Curr Protocols Toxicol 2008;34(suppl):12.13.1-12.13.16.
17. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
18. Maselli RA, Wollman RL, Leung C, Distad B, Palombi S, Richman DP, et al. Neuromuscular transmission in amyotrophic lateral sclerosis. Muscle Nerve 1993;16:1193-1203. (Pubitemid 23304857)
19. Sokal RR, Rohlf FJ. Biometry: the principles and practice of statistics in biological research, 3rd ed. New York: W.H. Freeman; 1995. 887 p.
20. Herkert NM, Eckert S, Eyer P, Bumm R, Weber G, Thiermann H, et al. Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors. Toxicology 2008;246:188-192.