Impaired spatial memory after ketamine administration in chronic low doses

Current Neuropharmacology

Volumn 9, Issue 1, 2011, Pages 251-255

  Venancio C ^a,b   Magalhaes A ^a   Antunes, L ^a,b   Summavielle, T ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Habituation; Ketamine; Long term effects; Memory; Spatial recognition

Indexed keywords

KETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LOCOMOTION; LONG TERM EXPOSURE; MEMORY DISORDER; NONHUMAN; OPEN FIELD TEST; RAT; SPATIAL DISCRIMINATION; SPATIAL MEMORY; TASK PERFORMANCE;

EID: 79953036071     PISSN: 1570159X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157015911795016912     Document Type: Article

References (29)

1. Annetta, M.G., Iemma, D., Garisto, C., Tafani, C., Proietti, R. Ketamine: new indications for an old drug. Curr. Drug Targets, 2005, 6, 789-794.
2. Ueyama, Y., Waselau, A.C., Wiese, A.J., Muir, W.W. Anesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine, ketamine injection in dogs. Vet. Anaesth. Analg., 2008, 35, 480-487.
3. Muetzelfeldt, L., Kamboj, S.K., Rees, H., Taylor, J., Morgan, C.J., Curran, H.V. Journey through the K-hole: phenomenological aspects of ketamine use. Drug Alcohol Depend., 2008, 95, 219-229.
4. Bell, R.F. Ketamine for chronic non-cancer pain. Pain, 2009, 141, 210-214.
5. Hocking, G., Cousins, M.J. Ketamine in chronic pain management: an evidence-based review. Anesth. Analg., 2003, 97, 1730-1739.
6. Imre, G., Fokkema, D.S., Den Boer, J.A., Ter Horst, G.J. Doseresponse characteristics of ketamine effect on locomotion,cognitive function and central neuronal activity. Brain Res. Bull., 2006, 69, 338-345.
7. Morgan, C.J., Muetzelfeldt, L., Curran, H.V. Ketamine use, cognition and psychological wellbeing: a comparison of frequent, infrequent and ex-users with polydrug and non-using controls. Addiction, 2009, 104, 77-87.
8. Razoux, F., Garcia, R., Lena, I. Ketamine, at a dose that disrupts motor behavior and latent inhibition, enhances prefrontal cortex synaptic efficacy and glutamate release in the nucleus accumbens. Neuropsychopharmacology, 2007, 32, 719-727.
9. Holcomb, H.H., Lahti, A.C., Medoff, D.R., Cullen, T., Tamminga, C.A. Effects of noncompetitive NMDA receptor blockade on anterior cingulate cerebral blood flow in volunteers with schizophrenia. Neuropsychopharmacology, 2005, 30, 2275-2282.
10. Enomoto, T., Floresco, S.B. Disruptions in spatial working memory, but not short-term memory, induced by repeated ketamine exposure. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2009, 33, 668-675.
11. Lewis, D.A., Gonzalez-Burgos, G. Neuroplasticity of neocortical circuits in schizophrenia. Neuropsychopharmacology, 2008, 33, 141-165.
12. Pratt, J.A., Winchester, C., Egerton, A., Cochran, S.M., Morris, B.J. Modelling prefrontal cortex deficits in schizophrenia: implications for treatment. Br. J. Pharmacol., 2008, 153(Suppl 1), S465-470.
13. Beraki, S., Diaz-Heijtz, R., Tai, F., Ogren, S.O. Effects of repeated treatment of phencyclidine on cognition and gene expression in C57BL/6 mice. Int. J. Neuropsychopharmacol., 2009, 12, 243-255.
14. Marquis, J.P., Killcross, S., Haddon, J.E. Inactivation of the prelimbic, but not infralimbic, prefrontal cortex impairs the contextual control of response conflict in rats. Eur. J. Neurosci., 2007, 25, 559-566.
15. Meen, M., Coudore-Civiale, M.A., Parry, L., Eschalier, A., Boucher, M. Involvement of N-methyl-D-aspartate receptors in nociception in the cyclophosphamide-induced vesical pain model in the conscious rat. Eur. J. Pain, 2002, 6, 307-314.
16. Pelissier, T., Alvarez, P., Hernandez, A. Effect of long-term ketamine administration on vocalization to paw pressure and on spinal wind-up activity in monoarthritic rats. Int. J. Neurosci., 2003, 113, 1305-1313.
17. Ennaceur, A., Michalikova, S., Bradford, A., Ahmed, S. Detailed analysis of the behavior of Lister and Wistar rats in anxiety, object recognition and object location tasks. Behav. Brain Res., 2005, 159, 247-266.
18. Gracia, L. S., Comim, C.M., Valvassori, S.S., Reurs, G.Z., Stertz, L., Kapczinski, F., Gavioli, E.C., Quevedo, J. Ketamine treatment reverses behavioral and Physiological alterations induced by chronic mild stress in rats. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2009, 33, 450-455.
19. Cvrcek, P. Side effects of ketamine in the long-term treatment of neuropathic pain. Pain Med., 2008, 9, 253-257.
20. Traverso, L.M., Ruiz, G., Camino, G., De la Casa, L.G. Ketamine blocks the formation of a gustatory memory trace in rats. Pharmacol. Biochem. Behav., 2008, 90, 305-311.
21. Leussis, M.P., Bolivar, V.J. Habituation in rodents: a review of behavior, neurobiology, and genetics. Neurosci. Biobehav. Rev., 2006, 30, 1045-1064.
22. Rosat, R., Da-Silva, R.C., Zanatta, M.S., Medina, J.H., Izquierdo, I. Memory consolidation of a habituation task: role of N-methyl-Daspartate, cholinergic muscarinic and GABA-A receptors in different brain regions. Braz. J. Med. Biol. Res., 1992, 25, 267-273.
23. Roullet, P., Mele, A., Ammassari-Teule, M. Involvement of glutamatergic and dopaminergic systems in the reactivity of mice to spatial and non-spatial change. Psychopharmacology (Berl), 1996, 126, 55-61.
24. Cerbone, A., Patacchioli, F.R., Sadile, A.G. A neurogenetic and morphogenetic approach to hippocampal functions based on individual differences and neurobehavioral covariations. Behav. Brain Res., 1993, 55, 1-16.
25. Henze, D.A., Urban, N.N., Barrionuevo, G. The multifarious hippocampal mossy fiber pathway: a review. Neuroscience, 2000, 98, 407-427.
26. Reid, C.A., Fabian-Fine, R., Fine, A. Postsynaptic calcium transients evoked by activation of individual hippocampal mossy fiber synapses. J. Neurosci., 2001, 21, 2206-2214.
27. Qin, L., Marrs, G.S., McKim, R., Dailey, M.E. Hippocampal mossy fibers induce assembly and clustering of PSD95-containing postsynaptic densities independent of glutamate receptor activation. J. Comp. Neurol., 2001, 440, 284-298.
28. Pitsikas, N., Boultadakis, A., Sakellaridis, N. Effects of subanesthetic doses of ketamine on rats' spatial and non-spatial recognition memory. Neuroscience, 2008, 154, 454-460.
29. Grace, A.A. Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain Res. Brain Res. Rev., 2000, 31, 330-341.