Musashi-1 expression in atherosclerotic arteries and its relevance to the origin of arterial smooth muscle cells: Histopathological findings and speculations

Atherosclerosis

Volumn 215, Issue 2, 2011, Pages 355-365

  Bobryshev, Yuri V ^a   Tran, Dinh ^b   Botelho, Natalia K ^a   Lord, Reginald V N ^a   Orekhov, Alexander N ^c,d  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST VINCENT S HOSPITAL   (Australia)

^c Institute of Chemical Problems of Ecology   (Russian Federation)

^d INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

Author keywords

Atherosclerosis; Coronary artery; Musashi 1; Smooth muscle cells; Stem cells; Vascular progenitor cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CELL MARKER; INTESTINAL STEM CELL MARKER; MUSASHI 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTERY INTIMA; ARTERY MUSCLE; ARTERY WALL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULATURE; MULTIPLEXED TANDEM POLYMERASE CHAIN REACTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ACTINS; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PATHOLOGIC; NERVE TISSUE PROTEINS; PLAQUE, ATHEROSCLEROTIC; RNA-BINDING PROTEINS; TUNICA INTIMA;

EID: 79953034674     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.01.013     Document Type: Article

References (64)

1. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999, 340:115-126.
2. Hansson G.K. Atherosclerosis-an immune disease: The Anitschkov Lecture 2007. Atherosclerosis 2009, 202:2-10.
3. Vanderlaan P.A., Reardon C.A. The unusual suspects: an overview of the minor leukocyte populations in atherosclerosis. J Lipid Res 2005, 46:829-838.
4. Galkina E., Ley K. Leukocyte influx in atherosclerosis. Curr Drug Targets 2007, 8:1239-1248.
5. Weber C., Zernecke A., Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol 2008, 8:802-815.
6. Bobryshev Y.V. Dendritic cells and their role in atherogenesis. Lab Invest 2010, 90:970-984.
7. McNeill E., Channon K.M., Greaves D.R. Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications. Clin Sci (Lond) 2010, 118:641-655.
8. Sata M., Saiura A., Kunisato A., et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002, 8:403-409.
9. Kashiwakura Y., Katoh Y., Tamayose K., et al. Isolation of bone marrow stromal cell-derived smooth muscle cells by a human SM22alpha promoter: in vitro differentiation of putative smooth muscle progenitor cells of bone marrow. Circulation 2003, 107:2078-2081.
10. Hillebrands J.L., Klatter F.A., Rozing J. Origin of vascular smooth muscle cells and the role of circulating stem cells in transplant arteriosclerosis. Arterioscler Thromb Vasc Biol 2003, 23:380-387.
11. Liu C., Nath K.A., Katusic Z.S., Caplice N.M. Smooth muscle progenitor cells in vascular disease. Trends Cardiovasc Med 2004, 14:288-293.
12. Sata M. Role of circulating vascular progenitors in angiogenesis, vascular healing, and pulmonary hypertension: lessons from animal models. Arterioscler Thromb Vasc Biol 2006, 26:1008-1014.
13. Xiao Q., Kiechl S., Patel S., et al. Endothelial progenitor cells, cardiovascular risk factors, cytokine levels and atherosclerosis-results from a large population-based study. PLoS One 2007, 2:e975.
14. Hristov M., Zernecke A., Schober A., Weber C. Adult progenitor cells in vascular remodeling during atherosclerosis. Biol Chem 2008, 389:837-844.
15. Hristov M., Weber C. Ambivalence of progenitor cells in vascular repair and plaque stability. Curr Opin Lipidol 2008, 19:491-497.
16. Liu C., Wang S., Metharom P., Caplice N.M. Myeloid lineage of human endothelial outgrowth cells circulating in blood and vasculogenic endothelial-like cells in the diseased vessel wall. J Vasc Res 2009, 46:581-591.
17. Hao H., Gabbiani G., Bochaton-Piallat M.L. Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol 2003, 23:1510-1520.
18. Hristov M., Weber C. Progenitor cell trafficking in the vascular wall. J Thromb Haemost 2009, 7(Suppl. 1):31-34.
19. Simper D., Stalboerger P.G., Panetta C.J., Wang S., Caplice N.M. Smooth muscle progenitor cells in human blood. Circulation 2002, 106:1199-1204.
20. Zoll J., Fontaine V., Gourdy P., et al. Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition. Cardiovasc Res 2008, 77:471-480.
21. Metharom P., Liu C., Wang S., et al. Myeloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo. Atherosclerosis 2008, 198:29-38.
22. Tillmanns J., Rota M., Hosoda T., et al. Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci USA 2008, 105:1668-1673.
23. Metharom P., Kumar A.H., Weiss S., Caplice N.M. A specific subset of mouse bone marrow cells has smooth muscle cell differentiation capacity-brief report. Arterioscler Thromb Vasc Biol 2010, 30:533-535.
24. Metharom P., Caplice N.M. Vascular disease: a new progenitor biology. Curr Vasc Pharmacol 2007, 5:61-68.
25. Iwata H., Sata M. Potential contribution of bone marrow-derived precursors to vascular repair and lesion formation: lessons from animal models of vascular diseases. Front Biosci 2007, 12:4157-4167.
26. Tanaka K., Sata M. Contribution of circulating vascular progenitors in lesion formation and vascular healing: lessons from animal models. Curr Opin Lipidol 2008, 19:498-504.
27. Iwata H., Sata M. Origin of cells that contribute to neointima growth. Circulation 2008, 117:3060-3061.
28. Tanaka K., Sata M. Role of vascular progenitor cells in cardiovascular disease. Curr Pharm Des 2009, 15:2760-2768.
29. van Oostrom O., Fledderus J.O., de Kleijn D., Pasterkamp G., Verhaar M.C. Smooth muscle progenitor cells: friend or foe in vascular disease?. Curr Stem Cell Res Ther 2009, 4:131-140.
30. Sirker A.A., Astroulakis Z.M., Hill J.M. Vascular progenitor cells and translational research: the role of endothelial and smooth muscle progenitor cells in endogenous arterial remodelling in the adult. Clin Sci (Lond) 2009, 116:283-299.
31. Hu Y., Davison F., Ludewig B., et al. Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells. Circulation 2002, 106:1834-1839.
32. Bentzon J.F., Weile C., Sondergaard C.S., et al. Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice. Arterioscler Thromb Vasc Biol 2006, 26:2696-2702.
33. Bentzon J.F., Sondergaard C.S., Kassem M., Falk E. Smooth muscle cells healing atherosclerotic plaque disruptions are of local, not blood, origin in apolipoprotein E knockout mice. Circulation 2007, 116:2053-2061.
34. Bentzon J.F., Falk E. Circulating smooth muscle progenitor cells in atherosclerosis and plaque rupture: current perspective and methods of analysis. Vascul Pharmacol 2010, 52:11-20.
35. Bachelet I., Levi-Schaffer F. Mast cells as effector cells: a co-stimulating question. Trends Immunol 2007, 28:360-365.
36. Le Bras A., Vijayaraj P., Oettgen P Molecular mechanisms of endothelial differentiation. Vasc Med 2010, Epub ahead of print: PMID: 20621955.
37. Auffray C., Sieweke M.H., Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol 2009, 27:669-692.
38. Okano H., Kawahara H., Toriya M., et al. Function of RNA-binding protein Musashi-1 in stem cells. Exp Cell Res 2005, 306:349-356.
39. Potten C.S., Booth C., Tudor G.L., et al. Identification of a putative intestinal stem cell and early lineage marker: Musashi-1. Differentiation 2003, 7:128-141.
40. Montgomery R.K., Breault D.T. Small intestinal stem cell markers. J Anat 2008, 213:52-58.
41. Yen T.H., Wright N.A. The gastrointestinal tract stem cell niche. Stem Cell Rev 2006, 2:203-212.
42. Schulenburg A., Cech P., Herbacek I., et al. CD44-positive colorectal adenoma cells express the potential stem cell markers musashi antigen (msi1) and ephrin B2 receptor (EphB2). J Pathol 2007, 213:152-160.
43. Fan L.F., Dong W.G., Jiang C.Q., et al. Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas. Int J Colorectal Dis 2010, 25:17-23.
44. Bobryshev Y.V., Freeman A.K., Botelho N.K., et al. Expression of the putative stem cell marker Musashi-1 in Barrett's esophagus and esophageal adenocarcinoma. Dis Esophagus 2010, 23:580-589.
45. Götte M., Wolf M., Staebler A., et al. Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma. J Pathol 2008, 215:317-329.
46. Moreira A.L., Gonen M., Rekhtman N., Downey R.J. Progenitor stem cell marker expression by pulmonary carcinomas. Mod Pathol 2010, 23:889-895.
47. Bobryshev Y.V., Lord R.S. Mapping of vascular dendritic cells in atherosclerotic arteries suggests their involvement in local immune-inflammatory reactions. Cardiovasc Res 1998, 37:799-810.
48. Bobryshev Y.V., Cherian S.M., Inder S.J., Lord R.S. Neovascular expression of VE-cadherin in human atherosclerotic arteries and its relation to intimal inflammation. Cardiovasc Res 1999, 43:1003-1017.
49. Grant K., Jerome W.G. Laser capture microdissection as an aid to ultrastructural analysis. Microsc Microanal 2002, 8:170-175.
50. Bobryshev Y.V. Intracellular localization of oxidized low-density lipoproteins in atherosclerotic plaque cells revealed by electron microscopy combined with laser capture microdissection. J Histochem Cytochem 2005, 53:793-797.
51. Keita M., Magy L., Richard L., Piaser M., Vallat J.M. LR white post-embedding colloidal gold method to immunostain MBP, P0, NF and S100 in glutaraldehyde-fixed peripheral nerve tissue. J Peripher Nerv Syst 2002, 7:128-133.
52. Simmons S.R., Sims P.A., Albrecht R.M. Alpha IIb beta 3 redistribution triggered by receptor cross-linking. Arterioscler Thromb Vasc Biol 1997, 17:3311-3320.
53. Bobryshev Y.V. Transdifferentiation of smooth muscle cells into chondrocytes in atherosclerotic arteries in situ: implications for diffuse intimal calcification. J Pathol 2005, 205:641-650.
54. Stanley K.K., Szewczuk E. Multiplexed tandem PCR: gene profiling from small amounts of RNA using SYBR Green detection. Nucleic Acids Res 2005, 33:e180.
55. Babaev V.R., Bobryshev Y.V., Stenina O.V., Tararak E.M., Gabbiani G. Heterogeneity of smooth muscle cells in atheromatous plaque of human aorta. Am J Pathol 1990, 136:1031-1042.
56. Bobryshev Y.V., Killingsworth M.C., Lord R.S., Grabs A.J. Matrix vesicles in the fibrous cap of atherosclerotic plaque: possible contribution to plaque rupture. J Cell Mol Med 2008, 12:2073-2082.
57. Bochaton-Piallat M.L., Gabbiani G. Modulation of smooth muscle cell proliferation and migration: role of smooth muscle cell heterogeneity. Handb Exp Pharmacol 2005, 170:645-663.
58. Majesky M.W. Vascular smooth muscle diversity: insights from developmental biology. Curr Atheroscler Rep 2003, 5:208-213.
59. Owens G.K. Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity. Novartis Found Symp 2007, 283:174-191.
60. McDonald O.G., Owens G.K. Programming smooth muscle plasticity with chromatin dynamics. Circ Res 2007, 100:1428-1441.
61. Bobryshev Y.V., Killingsworth M.C., Lord R.S. Spatial distribution of osteoblast-specific transcription factor Cbfa1 and bone formation in atherosclerotic arteries. Cell Tissue Res 2008, 333:225-235.
62. Hruska K.A. Vascular smooth muscle cells in the pathogenesis of vascular calcification. Circ Res 2009, 104:710-711.
63. Speer M.Y., Yang H.Y., Brabb T., et al. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circ Res 2009, 104:733-741.
64. Caplice N.M., Bunch T.J., Stalboerger P.G., et al. Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. Proc Natl Acad Sci USA 2003, 100:4754-4759.