MAM gene silencing leads to the induction of C3 and reduction of C4 and C5 side-chain aliphatic glucosinolates in Brassica napus

Molecular Breeding

Volumn 27, Issue 4, 2011, Pages 467-478

  Liu, Zheng ^a   Hammerlindl, Joe ^b   Keller, Wilf ^c   McVetty, Peter B E ^a   Daayf, Fouad ^a   Quiros, Carlos F ^d   Li, Genyi ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c Genome Prairie   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brassica napus; Gene silencing; Glucosinolate

Indexed keywords

AMINO ACIDS; CHAINS; GENETIC ENGINEERING; OILSEEDS; PLANTS (BOTANY);

% REDUCTIONS; 2-PROPENYL GLUCOSINOLATE; B.NAPUS; BRASSICA NAPUS; GENE SILENCING; GLUCOSINOLATE CONTENTS; GLUCOSINOLATES; RNA INTERFERENCE; SIDE-CHAINS; TRANSGENICS;

GENES;

ARABIDOPSIS; BRASSICA; BRASSICA JUNCEA; BRASSICA NAPUS; BRASSICA NAPUS VAR. NAPUS;

EID: 79953029685     PISSN: 13803743     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11032-010-9444-y     Document Type: Article

References (38)

1. Bednarek P, Pislewska-Bednarek M, Svatos A, Schneider B, Doubsky J, Mansurova M, Humphry M, Consonni C, Panstruga R, Sanchez-Vallet A, Molina A, Schulze-Lefert P (2009) A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense. Science 323: 101-106.
2. Beekwilder J, van Leeuwen W, van Dam NM, Bertossi M, Grandi V, Mizzi L, Soloviev M, Szabados L, Molthoff JW, Schipper B, Verbocht H, de Vos RC, Morandini P, Aarts MG, Bovy A (2008) The impact of the absence of aliphatic glucosinolates on insect herbivory in Arabidopsis. PLoS ONE 3: e2068.
3. Benderoth M, Textor S, Windsor AJ, Mitchell-Olds T, Gershenzon J, Kroymann J (2006) Positive selection driving diversification in plant secondary metabolism. Proc Natl Acad Sci USA 103: 9118-9123.
4. Celenza JL, Quiel JA, Smolen GA, Merrikh H, Silvestro AR et al (2005) The Arabidopsis ATR1 Myb transcription factor controls indolic glucosinolate homeostasis. Plant Physiol 137: 253-262.
5. Chen SX, Glawischnig E, Jorgensen K, Naur P, Jorgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA (2003) CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis. Plant J 33: 923-937.
6. Clay NK, Adio AM, Denoux C, Jander G, Ausubel FM (2009) Glucosinolate metabolites required for an Arabidopsis innate immune response. Science 323: 95-101.
7. de Kraker JW, Luck K, Textor S, Tokuhisa JG, Gershenzon J (2007) Two Arabidopsis genes (IPMS1 and IPMS2) encode isopropylmalate synthase, the branch point step in the biosynthesis of leucine. Plant Physiol 143: 970-986.
8. Fahey JW, Zhang Y, Talalay P (1997) Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA 94: 10367-10372.
9. Gigolashvili T, Berger B, Mock HP, Muller C, Weisshaar B et al (2007a) The transcription factor HIG1/MYB51 regulates indolic glucosinolate biosynthesis in Arabidopsis thaliana. Plant J 50: 886-901.
10. Gigolashvili T, Yatusevich R, Berger B, Muller C, Flugge UI (2007b) The R2R3-MYB transcription factor HAG1/MYB28 is a regulator of methionine-derived glucosinolate biosynthesis in Arabidopsis thaliana. Plant J 51: 247-261.
11. Grubb CD, Abel S (2006) Glucosinolate metabolism and its control. Trends Plant Sci 11: 89-100.
12. Halkier BA, Gershenzon J (2006) Biology and biochemistry of glucosinolates. Annu Rev Plant Biol 57: 303-333.
13. Hasan M, Friedt W, Pons-Kühnemann J, Freitag NM, Link K, Snowdon RJ (2008) Association of gene-linked SSR markers to seed glucosinolate content in oilseed rape (Brassica napus ssp. napus). Theor Appl Genet 116: 1035-1049.
14. Hirai MY, Sugiyama K, Sawada Y, Tohge T, Obayashi T et al (2007) Omics based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis. Proc Natl Acad Sci USA 104: 6478-6483.
15. Kliebenstein DJ, Kroymann J, Brown P, Figuth A, Pedersen D, Gershenzon J, Mitchell-Olds T (2001) Genetic control of natural variation in Arabidopsis thaliana glucosinolate accumulation. Plant Physiol 126: 811-825.
16. Kraling K, Robbelen G, Thies W, Herrmann M, Ahmadi MR (1990) Variation in seed glucosinolates in lines of Brassica napus. Plant Breed 105: 33-39.
17. Kroymann J, Textor S, Tokuhisa JG, Falk KL, Bartram S, Gershenzon J, Mitchell-Olds T (2001) A gene controlling variation in Arabidopsis glucosinolate composition is part of the methionine chain elongation pathway. Plant Physiol 127: 1077-1088.
18. Kroymann J, Donnerhacke S, Schnabelrauch D, Mitchell-Olds T (2003) Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus. Proc Natl Acad Sci USA 100: 14587-14592.
19. Li G, Quiros CF (2002) Genetic analysis, gene expression and molecular characterization of BoGSL-ELONG, a major gene involved in the aliphatic glucosinolate pathway of Brassica species. Genetics 162(4): 1937-1943.
20. Li G, Quiros CF (2003) The Brassica oleracea gene BoGSL-ALK regulates in planta alkenyl aliphatic glucosinolates in Arabidopsis thaliana. Theor Appl Genet 106: 1116-1121.
21. Li G, Gao M, Yang B, Quiros CF (2003) Gene to gene alignment between the Arabidopsis and Brassica oleracea genomes. Theor Appl Genet 107: 168-180.
22. Magrath R, Herron C, Giamoustaris A, Mithen R (1993) The inheritance of aliphatic glucosinolates in Brassica napus. Plant Breed 111: 55-72.
23. Magrath R, Bano F, Morgner M, Parkin I, Sharpe A, Lister C, Dean C, Turner J, Lydiate D, Mithen R (1994) Genetics of aliphatic glucosinolates. 1. Side chain elongation in Brassica napus and Arabidopsis thaliana. Heredity 72: 290-299.
24. Matthiessen JN, Shackleton MA (2005) Biofumigation: environmental impacts on the biological activity of diverse pure and plant-derived isothiocyanates. Pest Manag Sci 61: 1043-1051.
25. McVetty PBE, Fernando D, Li G, Tahir M, Zelmer C (2009) High-erucic acid, low-glucosinolate rapeseed (HEAR) cultivar development in Canada. In: Hou CT, Shaw JF (eds) Biocatalysis and agricultural biotechnology. CRC, Boca Raton, pp 43-61.
26. Moloney MM, Walker JM, Sharma KK (1989) High efficiency transformation of Brassica napus using Agrobacterium vectors. Plant Cell Rep 8: 238-242.
27. Nesi N, Delourme R, Brégeon M, Falentin C, Renard M (2008) Genetic and molecular approaches to improve nutritional value of Brassica napus L. seed. C R Biol 331: 763-771.
28. Nour-Eldin HH, Hansen BG, Norholm MHH, Jensen JK, Halkier BA (2006) Advancing uracil-excision based cloning towards an ideal technique for cloning PCR fragments. Nucleic Acids Res 34: e122.
29. Quiros CF, Grellet F, Sadowski J, Suzuki T, Li G, Wroblewski T (2001) Arabidopsis and Brassica comparative genomics: sequence, structure and gene content in the ABI1-Rps2-Ck1 chromosomal segment and related regions. Genetics 157: 1321-1330.
30. Reintanz B, Lehnen M, Reichelt M, Gershenzon J, Kowalczyk M, Sandberg G, Godde M, Uhl R, Palme K (2001) Bus, a bushy Arabidopsis CYP79F1 knockout mutant with abolished synthesis of short-chain aliphatic glucosinolates. Plant Cell 13: 351-367.
31. Schuster J, Knill T, Reichelt M, Gershenzon J, Binder S (2006) BRANCHED-CHAIN AMINOTRANSFERASE4 is part of the chain elongation pathway in the isoynthesis of methionine derived glucosinolates in Arabidopsis. Plant Cell 18: 2664-2679.
32. Sønderby IE, Hansen BG, Bjarnholt N, Ticconi C, Halkier BA et al (2007) A systems biology approach Identifies a R2R3 MYB gene subfamily with distinct and overlapping functions in regulation of aliphatic glucosinolates. PloS ONE 2: e1322.
33. Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, Gershenzon J (2004) Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle. Planta 218: 1026-1035.
34. Textor S, de Kraker JW, Hause B, Gershenzon J, Tokuhisa JG (2007) MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis. Plant Physiol 144: 60-71.
35. Vinjamoori V, Byrum JR, Hayes T, Das PK (2004) Challenges and opportunities in the analysis of raffinose oligosaccharides, pentosans. J Anim Sci 82: 319-328.
36. Zang YX, Kim JH, Park YD, Kim DH, Hong SB (2008) Metabolic engineering of aliphatic glucosinolates in Chinese cabbage plants expressing Arabidopsis MAM1, CYP79F1, and CYP83A1. BMB Rep 41: 472-478.
37. Zang YX, Kim HU, Kim JA, Lim MH, Jin M, Lee SC, Kwon SJ, Lee SI, Hong JK, Park TH, Mun JH, Seol YJ, Hong SB, Park BS (2009) Genome-wide identification of glucosinolate synthesis genes in Brassica rapa. FEBS J 276: 3559-3574.
38. Zhang GY, Talalay P, Cho C, Posner GH (1992) A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403.