Coupling to polymeric scaffolds stabilizes biofunctional peptides for intracellular applications

Molecular Pharmacology

Volumn 79, Issue 4, 2011, Pages 692-700

  Ruttekolk, Ivo R ^a   Chakrabarti, Alokta ^a   Richter, Martin ^c   Duchardt, Falk ^a   Glauner, Heike ^a   Verdurmen, Wouter P R ^a   Rademann, Jörg ^b,c   Brock, Roland ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CELL PENETRATING PEPTIDE; COPOLYMER; HYDROXYPROPYLMETHYLACRYLAMIDE; MOLECULAR SCAFFOLD; PEPTIDE; PROTEIN BID; UNCLASSIFIED DRUG;

ARTICLE; CELL LYSATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG CONJUGATION; DRUG HALF LIFE; DRUG STABILITY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEPARATION TECHNIQUE;

APOPTOSIS; HELA CELLS; HUMANS; INTRACELLULAR SPACE; JURKAT CELLS; METHACRYLATES; OLIGOPEPTIDES; PEPTIDES; POLYMERS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY;

EID: 79953008186     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.068296     Document Type: Article

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