메뉴 건너뛰기




Volumn 16, Issue 3, 2011, Pages 276-285

A review of an unfavorable subset of breast cancer: Estrogen receptor positive progesterone receptor negative

Author keywords

Estrogen receptor; Gefitinib; Growth factors; Progesterone receptor

Indexed keywords

ANASTROZOLE; ANTIESTROGEN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ESTROGEN; ESTROGEN RECEPTOR; EVEROLIMUS; FULVESTRANT; GEFITINIB; GROWTH FACTOR; LETROZOLE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLACEBO; PROGESTERONE RECEPTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; TAMOXIFEN; TEMSIROLIMUS; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 79952996052     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2010-0302     Document Type: Review
Times cited : (80)

References (34)
  • 1
    • 13944269488 scopus 로고    scopus 로고
    • Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance
    • Nakamura Y, Oka M, Soda H et al. Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. Cancer Res 2005; 65:1541-1546.
    • (2005) Cancer Res , vol.65 , pp. 1541-1546
    • Nakamura, Y.1    Oka, M.2    Soda, H.3
  • 2
    • 33847058518 scopus 로고    scopus 로고
    • Linkage of progestin and epidermal growth factor signaling: Phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth
    • Daniel AR, Qiu M, Faivre EJ et al. Linkage of progestin and epidermal growth factor signaling: Phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth. Steroids 2007;72:188-201.
    • (2007) Steroids , vol.72 , pp. 188-201
    • Daniel, A.R.1    Qiu, M.2    Faivre, E.J.3
  • 3
    • 12144269500 scopus 로고    scopus 로고
    • Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
    • Osborne CK, Shou J, Massarweh S et al. Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res 2005;11:865s-870s.
    • (2005) Clin Cancer Res , vol.11
    • Osborne, C.K.1    Shou, J.2    Massarweh, S.3
  • 4
    • 32944482243 scopus 로고    scopus 로고
    • Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy
    • Cui X, Schiff R, Arpino G et al. Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy. J Clin Oncol 2005; 23:7721-7735.
    • (2005) J Clin Oncol , vol.23 , pp. 7721-7735
    • Cui, X.1    Schiff, R.2    Arpino, G.3
  • 5
    • 79953011641 scopus 로고    scopus 로고
    • Expression of estrogen responsive genes in breast cancers correlates with plasma estradiol levels in postmenopausal women
    • San Antonio, Texas, December 13
    • Dunbier AK, Anderson H, Folkerd EJ et al. Expression of estrogen responsive genes in breast cancers correlates with plasma estradiol levels in postmenopausal women. Presented at the 31st Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, December 13, 2008.
    • (2008) Presented at the 31st Annual San Antonio Breast Cancer Symposium
    • Dunbier, A.K.1    Anderson, H.2    Folkerd, E.J.3
  • 6
    • 70249145117 scopus 로고    scopus 로고
    • EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer
    • Zhang Y, Su H, Rahimi M et al. EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer. Int J Cancer 2009;125: 2021-2028.
    • (2009) Int J Cancer , vol.125 , pp. 2021-2028
    • Zhang, Y.1    Su, H.2    Rahimi, M.3
  • 7
    • 24744443547 scopus 로고    scopus 로고
    • Estrogen receptor-positive, progesterone receptor-negative breast cancer: Association with growth factor receptor expression and tamoxifen resistance
    • Arpino G, Weiss H, Lee AV et al. Estrogen receptor-positive, progesterone receptor-negative breast cancer: Association with growth factor receptor expression and tamoxifen resistance. J Natl Cancer Inst 2005;97:1254-1261.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1254-1261
    • Arpino, G.1    Weiss, H.2    Lee, A.V.3
  • 8
    • 33744996743 scopus 로고    scopus 로고
    • Progesterone receptor in estrogen receptor-positive breast cancer: The association between HER-2 and lymph node involvement is age related
    • author reply
    • Neven P, Pochet N, Drijkoningen M et al. Progesterone receptor in estrogen receptor-positive breast cancer: The association between HER-2 and lymph node involvement is age related. J Clin Oncol 2006;24:2595; author reply 2595-2597.
    • (2006) J Clin Oncol , vol.24 , Issue.2595 , pp. 2595-2597
    • Neven, P.1    Pochet, N.2    Drijkoningen, M.3
  • 9
    • 34548536058 scopus 로고    scopus 로고
    • Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98
    • Viale G, Regan MM, Maiorano E et al. Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98. J Clin Oncol 2007;25: 3846-3852.
    • (2007) J Clin Oncol , vol.25 , pp. 3846-3852
    • Viale, G.1    Regan, M.M.2    Maiorano, E.3
  • 10
    • 59449087284 scopus 로고    scopus 로고
    • Molecular profiles of progesterone receptor loss in human breast tumors
    • Creighton CJ, Kent Osborne C, van de Vijver MJ et al. Molecular profiles of progesterone receptor loss in human breast tumors. Breast Cancer Res Treat 2009;114:287-299.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 287-299
    • Creighton, C.J.1    Kent, O.C.2    van de Vijver, M.J.3
  • 11
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 2000;406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 12
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • Chin K, DeVries S, Fridlyand J et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 2006;10:529-541.
    • (2006) Cancer Cell , vol.10 , pp. 529-541
    • Chin, K.1    Devries, S.2    Fridlyand, J.3
  • 13
    • 34247145491 scopus 로고    scopus 로고
    • Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade
    • Loi S, Haibe-Kains B, Desmedt C et al. Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J Clin Oncol 2007;25:1239-1246.
    • (2007) J Clin Oncol , vol.25 , pp. 1239-1246
    • Loi, S.1    Haibe-Kains, B.2    Desmedt, C.3
  • 14
    • 34249017035 scopus 로고    scopus 로고
    • Progesterone receptor status provides predictive value for adjuvant endocrine therapy in older estrogen receptor-positive breast cancer patients
    • Yu KD, Liu GY, Di GH et al. Progesterone receptor status provides predictive value for adjuvant endocrine therapy in older estrogen receptor-positive breast cancer patients. Breast 2007;16:307-315.
    • (2007) Breast , vol.16 , pp. 307-315
    • Yu, K.D.1    Liu, G.Y.2    Di, G.H.3
  • 15
    • 58149306378 scopus 로고    scopus 로고
    • Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status-a meta-analysis
    • Suzuki R, Orsini N, Saji S et al. Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status-a meta-analysis. Int J Cancer 2009;124:698-712.
    • (2009) Int J Cancer , vol.124 , pp. 698-712
    • Suzuki, R.1    Orsini, N.2    Saji, S.3
  • 16
    • 66149147056 scopus 로고    scopus 로고
    • Glycemic load, glycemic index and breast cancer risk in a prospective cohort of Swedish women
    • Larsson SC, Bergkvist L, and Wolk A. Glycemic load, glycemic index and breast cancer risk in a prospective cohort of Swedish women. Int J Cancer 2009;125:153-157.
    • (2009) Int J Cancer , vol.125 , pp. 153-157
    • Larsson, S.C.1    Bergkvist, L.2    Wolk, A.3
  • 17
    • 67650334402 scopus 로고    scopus 로고
    • Short-term prophylactic tamoxifen reduces the incidence of antiestrogen-resistant/estrogen receptor- positive/progesterone receptor-negative mammary tumors
    • Rose-Hellekant TA, Skildum AJ, Zhdankin O et al. Short-term prophylactic tamoxifen reduces the incidence of antiestrogen-resistant/estrogen receptor- positive/progesterone receptor-negative mammary tumors. Cancer Prev Res (Phila) 2009;2:496-502.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 496-502
    • Rose-Hellekant, T.A.1    Skildum, A.J.2    Zhdankin, O.3
  • 18
    • 1542354356 scopus 로고    scopus 로고
    • Analysis of time to recurrence in the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial according to estrogen receptor and progesterone receptor status
    • On behalf of the ATAC trialists group
    • Dowsett M, On behalf of the ATAC trialists group. Analysis of time to recurrence in the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial according to estrogen receptor and progesterone receptor status. Breast Cancer Res Treat 2003;82(suppl 1):S7.
    • (2003) Breast Cancer Res Treat , vol.82 , Issue.SUPPL. 1
    • Dowsett, M.1
  • 19
    • 77949754385 scopus 로고    scopus 로고
    • Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer
    • Cristofanilli M, Valero V, Mangalik A et al. Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer. Clin Cancer Res 2010;16:1904-1914.
    • (2010) Clin Cancer Res , vol.16 , pp. 1904-1914
    • Cristofanilli, M.1    Valero, V.2    Mangalik, A.3
  • 20
    • 79953000395 scopus 로고    scopus 로고
    • Endocrine therapy combined with signal transduction inhibitors a means to overcome resistance
    • San Antonio, Texas, December 11,
    • Johnston SRD. Endocrine therapy combined with signal transduction inhibitors a means to overcome resistance. Presented at the 31st Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, December 11, 2008.
    • (2008) Presented at the 31st Annual San Antonio Breast Cancer Symposium
    • Johnston, S.R.D.1
  • 21
    • 77953139611 scopus 로고    scopus 로고
    • Randomised phase II study of gefitinib or placebo in combination with tamoxifen in patients with hormone receptor positive metastatic breast cancer
    • San Antonio, TX, December
    • Osborne K, Neven P et al. Randomised phase II study of gefitinib or placebo in combination with tamoxifen in patients with hormone receptor positive metastatic breast cancer. Abstract presented at San Antonio Breast Cancer Symposium, San Antonio, TX, December 13-16, 2007.
    • (2007) Abstract Presented at San Antonio Breast Cancer Symposium , pp. 13-16
    • Osborne, K.1    Neven, P.2
  • 22
    • 19944408390 scopus 로고    scopus 로고
    • Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogenreceptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: A double-blind placebo-controlled phase II randomised trial
    • Polychronis A, Sinnett HD, Hadjiminas D et al. Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogenreceptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial. Lancet Oncol 2005;6:383-391.
    • (2005) Lancet Oncol , vol.6 , pp. 383-391
    • Polychronis, A.1    Sinnett, H.D.2    Hadjiminas, D.3
  • 23
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
    • Baselga J, Semiglazov V, van Dam P et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol 2009;27:2630-2637.
    • (2009) J Clin Oncol , vol.27 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    van Dam, P.3
  • 24
    • 73949105921 scopus 로고    scopus 로고
    • Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptorpositive metastatic breast cancer: Results from the randomized phase III TAnDEM study
    • Kaufman B, Mackey JR, Clemens MR et al. Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptorpositive metastatic breast cancer: Results from the randomized phase III TAnDEM study. J Clin Oncol 2009;27:5529-5537.
    • (2009) J Clin Oncol , vol.27 , pp. 5529-5537
    • Kaufman, B.1    Mackey, J.R.2    Clemens, M.R.3
  • 25
    • 34347213083 scopus 로고    scopus 로고
    • Greater survival after breast cancer in physically active women with high vegetable-fruit intake regardless of obesity
    • Pierce JP, Stefanick ML, Flatt SW et al. Greater survival after breast cancer in physically active women with high vegetable-fruit intake regardless of obesity. J Clin Oncol 2007;25:2345-2351.
    • (2007) J Clin Oncol , vol.25 , pp. 2345-2351
    • Pierce, J.P.1    Stefanick, M.L.2    Flatt, S.W.3
  • 26
    • 79953006042 scopus 로고    scopus 로고
    • - breast cancer are associated with genomic instability and Akt/mTOR signaling, and predict poor patient outcome better than clinically assigned PR status
    • San Antonio, Texas, December 14
    • - breast cancer are associated with genomic instability and Akt/mTOR signaling, and predict poor patient outcome better than clinically assigned PR status. Presented at the 30th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, December 14, 2007.
    • (2007) Presented at the 30th Annual San Antonio Breast Cancer Symposium
    • Creighton, C.J.1    Kent, O.C.2    van de Vijver, M.3
  • 28
    • 21244444556 scopus 로고    scopus 로고
    • Endocrine responsiveness: Understanding how progesterone receptor can be used to select endocrine therapy
    • Osborne CK, Schiff R, Arpino G et al. Endocrine responsiveness: Understanding how progesterone receptor can be used to select endocrine therapy. Breast 2005;14:458-465.
    • (2005) Breast , vol.14 , pp. 458-465
    • Osborne, C.K.1    Schiff, R.2    Arpino, G.3
  • 29
    • 0034688931 scopus 로고    scopus 로고
    • Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR and pS2, by immuno-histochemistry in predicting response to tamoxifen in metastatic breast cancer: A Southwest Oncology Group study
    • Elledge RM, Green S, Pugh R et al. Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR and pS2, by immuno-histochemistry in predicting response to tamoxifen in metastatic breast cancer: A Southwest Oncology Group study. Int J Cancer 2000;89:111-117.
    • (2000) Int J Cancer , vol.89 , pp. 111-117
    • Elledge, R.M.1    Green, S.2    Pugh, R.3
  • 30
    • 36048980544 scopus 로고    scopus 로고
    • Biologic and clinical characteristics of breast cancer with single hormone receptor positive phenotype
    • Rakha EA, El-Sayed ME, Green AR et al. Biologic and clinical characteristics of breast cancer with single hormone receptor positive phenotype. J Clin Oncol 2007;25:4772-4778.
    • (2007) J Clin Oncol , vol.25 , pp. 4772-4778
    • Rakha, E.A.1    El-Sayed, M.E.2    Green, A.R.3
  • 31
    • 0038688478 scopus 로고    scopus 로고
    • Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases
    • Bardou VJ, Arpino G, Elledge RM et al. Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases. J Clin Oncol 2003;21:1973-1979.
    • (2003) J Clin Oncol , vol.21 , pp. 1973-1979
    • Bardou, V.J.1    Arpino, G.2    Elledge, R.M.3
  • 32
    • 0037385522 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer
    • Cui X, Zhang P, Deng W et al. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer. Mol Endocrinol 2003;17:575-588.
    • (2003) Mol Endocrinol , vol.17 , pp. 575-588
    • Cui, X.1    Zhang, P.2    Deng, W.3
  • 33
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, Tibshirani R, Parker J et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A 2003;100:8418-8423.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 34
    • 35248889408 scopus 로고    scopus 로고
    • EGFR associated expression profiles vary with breast tumor subtype
    • Hoadley K, Weigman V, Fan C et al. EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 2007;8:258.
    • (2007) BMC Genomics , vol.8 , pp. 258
    • Hoadley, K.1    Weigman, V.2    Fan, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.