Diagnostic accuracy of clinical symptoms and signs in children with meningitis

Pediatric Emergency Care

Volumn 27, Issue 3, 2011, Pages 196-199

  Amarilyo, Gil ^a   Alper, Arik ^a   Ben Tov, Amir ^a   Grisaru Soen, Galia ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Brudzinski sign; Kernig sign; lumbar puncture; Meningitis; nuchal rigidity

Indexed keywords

GLUCOSE;

ADOLESCENT; ARTICLE; ASEPTIC MENINGITIS; BACTERIAL MENINGITIS; BRUDZINSKI SIGN; CEREBROSPINAL FLUID ANALYSIS; CHILD; DIAGNOSTIC ACCURACY; FEMALE; FONTANEL; GLASGOW COMA SCALE; HEADACHE; HERPES SIMPLEX VIRUS 1; HUMAN; INFANT; KERNIG SIGN; LEUKOCYTE; LEUKOCYTE COUNT; LISTERIA MONOCYTOGENES; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; NEISSERIA MENINGITIDIS; NUCHAL RIGIDITY; PHOTOPHOBIA; PREDICTIVE VALUE; PRESCHOOL CHILD; PROSPECTIVE STUDY; PROTEIN CEREBROSPINAL FLUID LEVEL; PSYCHOMOTOR DISORDER; RIGIDITY; SCHOOL CHILD; SEIZURE; SENSITIVITY AND SPECIFICITY; STREPTOCOCCUS PNEUMONIAE; SYMPTOMATOLOGY; VOMITING;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; INFANT; INTRACRANIAL PRESSURE; LEUKOCYTE COUNT; MALE; MENINGITIS; PHYSICAL EXAMINATION; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPINAL PUNCTURE;

EID: 79952987364     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e31820d6543     Document Type: Article

References (16)

1. Sáez-Llorens X, McCracken GH Jr. Bacterial meningitis in children. Lancet. 2003;361:2139-2148. (Pubitemid 36782263)
2. Bonsu BK, Harper MB. Differentiating acute bacterial meningitis from acute viral meningitis among children with cerebrospinal fluid pleiocytosis: a multivariable regression model. Pediatr Infect Dis J. 2004;23:511-517. (Pubitemid 38802295)
3. Oostenbrink R, Moons KG, Donders AR, et al. Prediction ofbacterial meningitis in children with meningeal signs: reduction oflumbar punctures. Acta Paediatr. 2001;90:611-617. (Pubitemid 32595862)
4. Nigrovic LE, Kuppermann N, Macias CG, et al. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk ofbacterial meningitis. JAMA. 2007;297:52-60. (Pubitemid 46041726)
5. Freedman SB, Marrocco A, Pirie J, et al. Predictors ofbacterial meningitis in the era after Haemophilus influenzae. Arch Pediatr Adolesc Med. 2001;155:1301-1306. (Pubitemid 33139582)
6. Dubos F, De la Rocque F, Levy C, et al. Sensitivity of the bacterial meningitis score in 889 children with bacterial meningitis. JPediatr. 2008;152:378-382. (Pubitemid 351231885)
7. Dubos F, Martinot A, Gendrel D, et al. Clinical decision rules for evaluating meningitis in children. Curr Opin Neurol. 2009;22:288-293.
8. Oostenbrink R, Moons KG, Derksen-Lubsen AG, et al. A diagnostic decision rule for management of children with meningeal signs. Eur JEpidemiol. 2004;19:109-116. (Pubitemid 38374559)
9. Nigrovic LE, Malley R, Kuppermann N. Cerebrospinal fluid pleocytosis in children in the era ofbacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis. Pediatr Emerg Care. 2009;25:112-117.
10. Oostenbrink R, Moons KG, Theunissen CC, et al. Signs ofmeningeal irritation at the emergency department: how often bacterial meningitis? Pediatr Emerg Care. 2001;17:161-164. (Pubitemid 32567850)
11. Oliver LG, Harwoord-Nuss AL. Bacterial meningitis in children and infants. J Emerg Med. 1993;11:555-564.
12. Valmari P, Peltola H, Ruuskanen O, et al. Childhood bacterial meningitis: initial symptoms and signs related to age, and reasons for consulting a physician. Eur JPediatr. 1987;146:515-518. (Pubitemid 18053158)
13. Elmore JG, Horwitz RI, Quagliarello VJ. Acute meningitis with a negative Gram's stain: clinical and management outcomes in 171 episodes. Am JMed. 1996;100:78-84. (Pubitemid 26049330)
14. Uchihara T, Tsukagoshi H. Jolt accentuation ofheadache: the most sensitive sign of CSF pleocytosis. Headache. 1991;31:167-171.
15. Thomas KE, Hasbun R, Jekel J, et al. The diagnostic accuracy of Kernig's sign, Brudzinski's sign, and nuchal rigidity in adults with suspectedmeningitis. Clin Infect Dis. 2002;35:46-52. (Pubitemid 34666859)
16. Levy M, Wong E, Fried D. Diseases that mimic meningitis. Analysis of 650 lumbar punctures. Clin Pediatr (Phila). 1990;29:254-255, 258-261.