Differentiating acute bacterial meningitis from acute viral meningitis among children with cerebrospinal fluid pleocytosis: A multivariable regression model

Pediatric Infectious Disease Journal

Volumn 23, Issue 6, 2004, Pages 511-517

  Bonsu, Bema K ^a   Harper, Marvin B ^b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Cerebrospinal fluid tests; Children; Logistic regression modeling; Meningitis

Indexed keywords

PROTEIN;

ACCURACY; ADULT; AGE; ARTICLE; BACTERIAL MENINGITIS; CEREBROSPINAL FLUID; CHILD; CONTROLLED STUDY; ENTEROVIRUS; HUMAN; INFANT; MAJOR CLINICAL STUDY; MODEL; MULTIVARIATE ANALYSIS; NEUTROPHIL; PLEOCYTOSIS; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; SENSITIVITY AND SPECIFICITY; SYSTEMATIC REVIEW; VIRUS MENINGITIS;

ACUTE DISEASE; ADOLESCENT; AGE FACTORS; CEREBROSPINAL FLUID PROTEINS; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; INFANT; LEUKOCYTE COUNT; LOGISTIC MODELS; MALE; MENINGITIS, BACTERIAL; MENINGITIS, VIRAL; MULTIVARIATE ANALYSIS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SPINAL PUNCTURE;

EID: 3042640720     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.inf.0000129689.58211.9e     Document Type: Article

References (19)

1. Spanos A, Harrell FEJr., Durack DT. Differential diagnosis of acute meningitis. An analysis of the predictive value of initial observations. JAMA. 1989;262:2700-2707.
2. Geiseler PJ, Nelson KE, Levin S, Reddi KT, Moses VK. Community-acquired purulent meningitis: a review of 1316 cases during the antibiotic era, 1954-1976. Rev Infect Dis. 1980;2:725-745.
3. Wald ER, Kaplan SL, Mason EOJr., et al. Dexamethasone therapy for children with bacterial meningitis: Meningitis Study Group. Pediatrics. 1995;95:21-28.
4. Marton KI, Gean AD. The spinal tap: a new look at an old test. Ann Intern Med. 1986;104:840-848.
5. Nigrovic LE, Kuppermann N, Malley R. Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era. Pediatrics. 2002;110:712-719.
6. Hoen B, Viel JF, Paquot C, Gerard A, Canton P. Multivariate approach to differential diagnosis of acute meningitis. Eur J Clin Microbiol Infect Dis. 1995;14:267-274.
7. Baty V, Viel JF, Schuhmacher H, Jaeger F, Canton P, Hoen B. Prospective validation of a diagnosis model as an aid to therapeutic decision-making in acute meningitis. Eur J Clin Microbiol Infect Dis. 2000;19:422-426.
8. Jaeger F, Leroy J, Duchene F, et al. Validation of a diagnosis model for differentiating bacterial from viral meningitis in infants and children under 3.5 years of age. Eur J Clin Microbiol Infect Dis. 2000;19:418-421.
9. Leblebicioglu H, Esen S, Bedir A, Gunaydin M, Sanic A. The validity of Spanos' and Hoen's models for differential diagnosis of meningitis. Eur J Clin Microbiol Infect Dis. 1996;15:252-254.
10. Harrell FE. Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis. New York, NY: Springer, 2001.
11. Royston P, Altman DG. Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling. Appl Stat. 1994;43:429-467.
12. Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed. New York, NY: Wiley, 2000.
13. Swets JA. Measuring the accuracy of diagnostic systems. Science. 1988;240:1285-1293.
14. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143:29-36.
15. Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test, B: what are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA. 1994;271:703-707.
16. Connolly KJ, Hammer SM. The acute aseptic meningitis syndrome. Infect Dis Clin North Am. 1990;4:599-622.
17. Rantakallio P, Leskinen M, von Wendt L. Incidence and prognosis of central nervous system infections in a birth cohort of 12,000 children. Scand J Infect Dis. 1986;18:287-294.
18. Mandell GL, Douglas RG, Bennett JE, Dolin R. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 5th ed. Philadelphia, PA: Churchill Livingstone; 2000.
19. Negrini B, Kelleher KJ, Wald ER. Cerebrospinal fluid findings in aseptic versus bacterial meningitis. Pediatrics. Feb 2000;105(2):316-319.