The time course of visual backward masking deficits in schizophrenia

Journal of Integrative Neuroscience

Volumn 10, Issue 1, 2011, Pages 33-45

  Skottun, Bernt C ^a   Skoyles, John R ^b,c  

^a Ullevålsalleen 4C   (Norway)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c LONDON SCHOOL OF ECONOMICS   (United Kingdom)

Author keywords

ISI; latency; Magnocellular; SOA; vision

Indexed keywords

ARTICLE; AUDITORY STIMULATION; BRAIN REGION; BRAIN STEM RESPONSE; HUMAN; LATENT PERIOD; MAGNOCELLULAR NUCLEUS; NERVE CELL; NERVE MALFORMATION; PARVOCELLULAR NEURON; PREDICTION; SCHIZOPHRENIA; STIMULUS RESPONSE; TASK PERFORMANCE; TIME; VISUAL CORTEX; VISUAL MASKING;

EID: 79952934896     PISSN: 02196352     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0219635211002609     Document Type: Article

References (111)

1. Amassian VE, Cracco RQ, Maccabee PJ, Cracco JB, Rudell A, Eberle L, Suppression of visual perception by magnetic coil stimulation of human occipital cortex, Electroencephalogr Clin Neurophysiol 74:458-462, 1989. (Pubitemid 20000342)
2. Bedwell JS, Orem DM, Rassovsky Y, Allen LG, Sutterby SR, A potential qualitative endophenotype for schizophrenia: Backward masking response to red light, Psychiatr Res 166:166-173, 2009.
3. Blakemore C, Vital-Durand F, Organization and post-natal development of monkey's lateral geniculate nucleus, J Physiol (Lond) 380:453-491, 1986. (Pubitemid 17180097)
4. Bogren LY, Bogren IB, Early visual information processing and the Defence Mechanism Test in schizophrenia, Acta Psychiatrica Scandinavica 99:460-465, 1999. (Pubitemid 29272278)
5. Braff DL, Impaired speed of information processing in nonmedicated schizotypal patients, Schizophr Bull 7:499-508, 1981. (Pubitemid 11025918)
6. Braff DL, Sensory input deficits and negative symptoms in schizophrenic patients, Am J Psychiatry, 146:1006-1011, 1989. (Pubitemid 19197977)
7. Braff DL, Saccuzzo DP, Information processing dysfunction in paranoid schizophrenia: A two-factor deficit, Am J Psychiatry 138:1051-1056, 1981. (Pubitemid 11012804)
8. Braff DL, Saccuzzo DP, Effect of antipsychotic medication on speed of information processing in schizophrenic patients, Am J Psychiatry 139:1127-1130, 1982. (Pubitemid 12051591)
9. Braff DL, Saccuzzo DP, The time course of information-processing deficits in schizophrenia, Am J Psychiatry 142:170-174, 1985. (Pubitemid 15165399)
10. Breitmeyer BG, Ogmen H, Recent models and findings in visual backward masking: A comparison, review, and update, Percept Psychophys 62:1572-1595, 2000.
11. Brittain PJ, Surguladze S, McKendrick AM, Ffytche DH, Backward and forward masking in schizophrenia and its relation to global motion and global form perception, Schizophr Res 124:134-141, 2010.
12. Butler PD, DeSanti LA, Maddox J, Harkavy-Friedman JM, Amador XF, Goetz RR, Javitt DC, Gorman JM, Visual backward-masking deficits in schizophrenia: Relationship to visual pathway function and symptomatology, Schizophr Res 59:199-209, 2002. (Pubitemid 35284693)
13. Butler PD, Harkavy-Friedman JM, Amador XF, Gorman JM, Backward masking in schizophrenia: Relationship to medication status, neuropsychological functioning, and dopamine metabolism, Biol Psychiatry 40:295-298, 1996. (Pubitemid 26298206)
14. Butler PD, Javitt DC, Early-stage visual processing deficits in schizophrenia Curr Opin Psychiatry 18:151-157, 2005. (Pubitemid 40824447)
15. Butler PD, Martinez A, Foxe JJ, Kim D, Zemon V, Silipo G, Mahoney J, Shpaner M, JalbrzikowskiM, Javitt DC, Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments, Brain 130:417-430, 2007. (Pubitemid 46181095)
16. Cadenhead KS, Geyer MA, Butler RW, Perry W, Sprock J, Braff DL, Information processing deficits of schizophrenia patients: Relationship to clinical ratings, gender and medication status, Schizophr Res 28: 51-62, 1997. (Pubitemid 27522790)
17. Cadenhead KS, Serper Y, Braff DL, Transient versus sustained visual channels in the visual backward masking deficits of schizophrenia patients, Biol Psychiatry 43:132-138, 1998. (Pubitemid 28079082)
18. Corthout E, Uttl B, Ziemann U, Cowey A, Hallett M, Two periods of processing in the (circum)striate visual cortex as revealed by transcranial magnetic stimulation, Neuropsychologia 37:137-145, 1999. (Pubitemid 29062318)
19. Dorph-Petersen KA, Caric D, Saghafi R, Zhang W, Sampson AR, Lewis DA, Volume and neuron number of the lateral geniculate nucleus in schizophrenia and mood disorders, Acta Neuropathol 117:369-384, 2009.
20. Dreher B, Fukada Y, Rodieck RW, Identification, classification and anatomical segregation of cells with X-like and Y-like properties in the lateral geniculate nucleus of old-world primates, J Physiol (Lond) 258:433-452, 1976.
21. Francis G, Cortical dynamics of lateral inhibition: Metacontrast masking, Psychol Rev 104:572-594, 1997. (Pubitemid 127457190)
22. Gielen CC, Spatio-Temporal and Chromatic Properties of Visual Neurones in the Rhesus Monkey Geniculate Nucleus, Unpublished doctoral dissertation, University of Nijmegen, Nijmegen, Holland, 1980.
23. Goghari VM, Sponheim SR, Divergent backward masking performance in schizophrenia and bipolar disorder: Association with COMP, Am J Med Genetics Part B 147B:223-227, 2008. (Pubitemid 351355284)
24. Granholm E, Verney SP, Pupillary responses and attentional allocation problems on the backward masking task in schizophrenia, Int J Psychophysiol 52:37-51, 2004. (Pubitemid 38328522)
25. Green MF, Butler PD, Chen Y, Geyer MA, Silverstein S, Wynn JK, Yoon JH, Zemon V, Perception measurement in clinical trials of schizophrenia: Promising paradigms from CNTRICS, Schizophr Bull 35:163-181, 2009.
26. Green MF, Nuechterlein KH, Mintz J, Backward masking in schizophrenia and mania. I. Specifying a mechanism, Arch Gen Psychiatry 51:939-944, 1994. (Pubitemid 24371863)
27. Green MF, Nuechterlein KH, Mintz J, Backward masking in schizophrenia and mania. II. Specifying the visual channels, Arch Gen Psychiatry 51:945-951, 1994. (Pubitemid 24371864)
28. Green MF, Nuechterlein KH, Breitmeyer B, Mintz J, Backward masking in unmedicated schizophrenic patients in psychotic remission: Possible reflection of aberrant cortical oscillation, Am J Psychiatry 156:1367-1373, 1999. (Pubitemid 29416532)
29. Green MF, Nuechterlein KH, Breitmeyer B, Tsuang J,Mintz J, Forward and backward visual masking in schizophrenia: Influence of age, Psychol Med 33:887-895, 2003. (Pubitemid 36874668)
30. Green MF, Mintz J, Salveson D, Nuechterlein KH, Breitmeyer B, Light GA, Braff DL, Visual masking as a probe for abnormal gamma range activity in schizophrenia, Biol Psychiatry 53:1113-1119, 2003. (Pubitemid 36695086)
31. Green MF, Lee J, Cohen MS, Engel SA, Korb AS, Nuechterlein KH, Wynn JK, Glahn DC, Functional neuroanatomy of visual masking deficits in schizophrenia, Arch Gen Psychiatry, 66:1295-1303, 2010.
32. Green MF, Wynn JK, Breitmeyer B, Mathisand KI, Nuechterlein KH, Visual masking by object substitution in schizophrenia, Psychol Med 16:1-8, 2010.
33. Harvey PD, Keefe RS, Moskowitz J, Putnam KM, Mohs RC, Davis KL, Attentional markers of vulnerability to schizophrenia: Performance of medicated and unmedicated patients and normals, Psychiatry Res 33:179-188, 1990. (Pubitemid 20289101)
34. Herzog MH, Kopmann S, Brand A, Intact figure-ground segmentation in schizophrenia, Psychiatry Res 129:55-63, 2004. (Pubitemid 39574437)
35. Javitt DC, When doors of perception close: Bottom-up models of disrupted cognition in schizophrenia, Ann Rev Clin Psychol 5:249-275, 2009.
36. Kantrowitz JT, Butler PD, Schecter I, Silipo G, Javitt DC, Seeing the world dimly: The impact of early visual deficits on visual experience in schizophrenia, Schizophr Bull 35:1085-1094, 2009.
37. Kaplan E, Shapley RM, X and Y cells in the lateral geniculate nucleus of Macaque monkeys, J Physiol (Lond) 330:125-143, 1982. (Pubitemid 12024562)
38. Keri S, Antal A, Szekeres G, Benedek G, Janka Z, Visual information processing in patients with schizophrenia: Evidence for the impairment of central mechanisms, Neurosci Lett 293:69-71, 2000.
39. Keri S, Kelemen G, Benedek G, Janka Z, Different trait markers for schizophrenia and bipolar disorder: A neurocognitive approach, Psychol Med 31:915-922, 2001. (Pubitemid 32621900)
40. Keri S, Szendi I, Kelemen O, Benedek G, Janka Z, Remitted schizophrenia-spectrum patients with spared working memory show information processing abnormalities, Eur Arch Psychiatry Clin Neurosci 251:60-65, 2001. (Pubitemid 32488033)
41. Keri S, Kelemen O, Benedek G, Janka Z, Vernier threshold in patients with schizophrenia and their unaffected siblings, Neuropsychology 18:537-542, 2004. (Pubitemid 38944389)
42. Kilavik BE, Silveira LC, Kremers J, Spatial receptive field properties of lateral geniculate cells in the owl monkey (Aotus azarae) at different contrasts: A comparative study, Eur J Neurosci 26:992-1006, 2007. (Pubitemid 47274606)
43. Kim D, Wylie G, Pasternak R, Butler PD, Javitt DC, Magnocellular contributions to impaired motion processing in schizophrenia, Schizophr Res 82:1-8, 2006. (Pubitemid 43202643)
44. Kim D, Zemon V, Saperstein A, Butler PD, Javitt DC, Dysfunction of earlystage visual processing in schizophrenia: Harmonic analysis, Schizophr Res 76:55-65, 2005. (Pubitemid 40824560)
45. Knight RA, Elliott DS, Freedman EG, Short-term visual memory in schizophrenics, J Abnorm Psychol 94:427-442, 1985. (Pubitemid 16159631)
46. Koelkebeck K, Ohrmann P, Hetzel G, Arolt V, Suslow T, Visual backward masking: Deficits in locating targets are specific to schizophrenia and not related to intellectual decline, Schizophr Res 78:261-268, 2005. (Pubitemid 41254028)
47. Lachica EA, Beck PD, Casagrande VA, Parallel pathways in macaque monkey striate cortex: Anatomically defined columns in layer III, Proc Natl Acad Sci U S A 89:3566-3570, 1992.
48. Lee J, Nuechterlein KH, Subotnik KL, Sugar CA, Ventura J, Gretchen-Doorly D, Kelly K, Green MF, Stability of visual masking performance in recent-onset schizophrenia: A 18-month longitudinal study, Schizophr Res 103:266-274, 2008.
49. Legge GE, Spatial frequency masking in human vision: Binocular interactions, J Opt Soc Am A 69:838-847, 1979.
50. Levitt JB, Schumer RA, Sherman SM, Spear PD, Movshon JA, Visual response properties of neurons in the LGN of normally reared and visually deprived macaque monkeys, J Neurophysiol 85:2111-2129, 2001. (Pubitemid 32440689)
51. Levitt JB, Yoshioka T, Lund JS, Intrinsic cortical connections in macaque visual area V2: Evidence for interaction between different functional streams, J Comp Neurol 342:551-570, 1994. (Pubitemid 24125721)
52. Luber B, Stanford, AD, Malaspina D, Lisanby SH, Revisiting the backward masking deficit in schizophrenia: Individual differences in performance and modeling with transcranial magnetic stimulation, Biol Psychiatry 62:793-799, 2007. (Pubitemid 47374641)
53. Maeda K, Yamamoto H, Fukunaga M, Umeda M, Tanaka C, Ejima Y, Neural correlates of color-selective metacontrast in human early retinotopic areas, J Neurophysiol 104:2291-2301, 2010.
54. Marrocco RT, Sustained and transient cells in monkey lateral geniculate nucleus: Conduction velocities and response properties, J Neurophysiol 39:340-353, 1976.
55. Martin KAC, Parallel pathways converge, Curr Biol 2:555-557, 1992.
56. Maunsell JH, Ghose GM, Assad JA, McAdams CJ, Boudreau CE, Noerager BD, Visual response latencies of magnocellular and parvocellular LGN neurons in macaque monkeys, Vis Neurosci 16:1-14, 1999. (Pubitemid 29150495)
57. Maunsell JH, Gibson JR, Visual response latencies in striate cortex of the macaque monkey, J Neurophysiol 68:1332-1344, 1992.
58. McClure RK, The visual backward masking deficit in schizophrenia, Prog Neuropsychopharmacol Biol Psychiatry 25:301-311, 2001. (Pubitemid 32234651)
59. Merigan WH, Byrne CE, Maunsell JH, Does primate motion perception depend on the magnocellular pathway? J Neurosci 11:3422-3429, 1991.
60. Merigan WH, Maunsell JH, How parallel are the primate visual pathways? Ann Rev Neurosci 16:369-402, 1993. (Pubitemid 23074013)
61. Merritt RD, Balogh DW, Backward masking spatial frequency effects among hypothetically schizotypal individuals, Schizophr Bull 15:573-583, 1989.
62. Nealey TA, Maunsell JHR, Magnocellular and parvocellular contributions to the responses of neurons in macaque striate cortex, J Neurosci 14:2069-2079, 1994. (Pubitemid 24108116)
63. Noguchi Y, Kakigi R, Neural mechanisms of visual backward masking revealed by high temporal resolution imaging of human brain, Neuroimage 27:178-187, 2005. (Pubitemid 40966893)
64. Nowak LG, Bullier J, The timing of information transfer in the visual system, in Rockland K, Kaas J, Peters A (eds.), Cerebral Cortex, Plenum, New York, pp. 204- 241, 1997.
65. Nowak LG, Munk MH, Girard P, Bullier J, Visual latencies in areas V1 and V2 of the macaque monkey, Vis Neurosci 12:371-384, 1995.
66. Ogmen H, Breitmeyer BG, Todd S, Mardon L, Target recovery in metacontrast: The effect of contrast, Vis Res 46:4726-4734, 2006. (Pubitemid 44750049)
67. Rassovsky Y, Green MF, Nuechterlein KH, Breitmeyer B, Mintz J, Paracontrast and metacontrast in schizophrenia: Clarifying the mechanism for visual masking deficits, Schizophr Res 71:485-492, 2004. (Pubitemid 39330526)
68. Rassovsky Y, Green MF, Nuechterlein KH, Breitmeyer B, Mintz J, Modulation of attention during visual masking in schizophrenia, Am J Psychiatry 162:1533-1535, 2005. (Pubitemid 41105571)
69. Rolls ET, Tovee MJ, Panzeri S, The neurophysiology of backward visual masking: Information analysis, J Cognit Neurosci 11:300-311, 1999. (Pubitemid 29281527)
70. Rund BR, Backward-masking performance in chronic and nonchronic schizophrenics, affectively disturbed patients, and normal control subjects, J Abnorm Psychol 102:74-81, 1993. (Pubitemid 23089565)
71. Rund BR, Landrø NI, Orbeck AL, Stability in backward masking performance in schizophrenics, affectively disturbed patients, and normal subjects, J Nerv Ment Dis 181:233-237, 1993. (Pubitemid 23233329)
72. Saccuzzo DP, Braff DL, Information-processing abnormalities: Trait- and statedependent components, Schizophr Bull 12:447-459, 1986.
73. Saccuzzo DP, Braff DL, Sprock J, The effect of mental retardation and schizophrenia on information processing, J Nerv Mental Dis 170:102-106, 1982. (Pubitemid 12180839)
74. Saccuzzo DP, Hirt M, Spencer TJ, Backward masking as a measure of attention in schizophrenia, J Abnorm Psychol 83:512-522, 1974.
75. Saccuzzo DP,Michael B, Speed of information-processing and structural limitations by mentally retarded and dual-diagnosed retarded-schizophrenic persons, Am J Mental Deficiency 89:187-194, 1984. (Pubitemid 14032143)
76. Saccuzzo DP, Schubert DL, Backward masking as a measure of slow processing in schizophrenia spectrum disorders, J Abnorm Psychol 90:305-312, 1981.
77. Saccuzzo DS, Cadenhead KS, Braff DL, Backward versus forward visual masking deficits in schizophrenic patients: Centrally, not peripherally, mediated? Am J Psychiatry 153:1564-1570, 1996. (Pubitemid 26406166)
78. Sawatari A, Callaway EM, Convergence of magno- and parvocellular pathways in layer 4B of macaque primary visual cortex, Nature 380:442-446, 1996. (Pubitemid 26102721)
79. Schechter I, Butler PD, Jalbrzikowski M, Pasternak R, Saperstein, AM, Javitt DC, A new dimension of sensory dysfunction: Stereopsis deficits in schizophrenia, Biol Psychiatry 60:1282-1284, 2006. (Pubitemid 44693538)
80. Schechter I, Butler PD, Silipo G, Zemon V, Javitt DC, Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia, Schizophr Res 64:91-101, 2003. (Pubitemid 37412331)
81. Schiller PH, Logothetis NK, The color-opponent and broad-band channels of the primate visual system, Trend Neurosci 13:392-398, 1990. (Pubitemid 20297462)
82. SchmoleskyMT,Wang Y, Hanes DP, Thompson KG, Leutgeb S, Schall, JD, Leventhal AG, Signal timing across the macaque visual system, J Neurophysiol 79:3272-3278, 1998. (Pubitemid 28317052)
83. Schroeder CE, Tenke CE, Arezzo JC, Vaughan HG Jr, Timing and distribution of flash-evoked activity in the lateral geniculate nucleus of the alert monkey, Brain Res 477:183-195, 1989. (Pubitemid 19026952)
84. Schwartz BD, Winstead DK, Visible persistence in paranoid schizophrenics, Biol Psychiatry 23, 3-12, 1988. (Pubitemid 18008081)
85. Sclar G, Maunsell JH, Lennie P, Coding of image contrast in central visual pathways of the macaque monkey, Vis Res 30:1-10, 1990. (Pubitemid 20033234)
86. Selemon LD, Begovic A, Stereologic analysis of the lateral geniculate nucleus of the thalamus in normal and schizophrenic subjects, Psychiatry Res 151:1-10, 2007. (Pubitemid 46634640)
87. Sergi MJ, Green MF, Social perception and early visual processing in schizophrenia, Schizophr Res 59:233-241, 2003. (Pubitemid 35284697)
88. Sincich LC, Horton JC, Divided by cytochrome oxidase: A map of the projections from V1 to V2 in macaques, Science 295:1734-1737, 2002. (Pubitemid 34202912)
89. Skottun BC, On the use of metacontrast to assess magnocellular function in dyslexic readers, Percept Psychophysic 63:1271-1274, 2001.
90. Skottun BC, On the use of red stimuli to isolate magnocellular responses in psychophysical experiments: A perspective, Vis Neurosci 21:63-68, 2004. (Pubitemid 38736048)
91. Skottun BC, Skoyles JR, Contrast sensitivity and magnocellular functioning in schizophrenia, Vis Res 47:2923-2933, 2007. (Pubitemid 47513177)
92. Skottun BC, Skoyles J, A few remarks on assessing magnocellular sensitivity in Schizophrenic patients, Brain 130:e83, 2007. (Pubitemid 350033956)
93. Skottun BC, Skoyles JR, Metacontrast, target recovery, and the magno- and parvocellular systems: A perspective, Vis Neurosci 24:177-181, 2007. (Pubitemid 47093976)
94. Skottun BC, Skoyles JR, Reply to Kèri, S, The magnocellular system and schizophrenia, Vis Res 48:1183-1185, 2008.
95. Skottun BC, Skoyles JR, Are masking abnormalities in schizophrenia limited to backward masking? Int J Neurosci 119:88-104, 2009.
96. Skottun BC, Skoyles JR, Stereopsis and magnocellular sensitivity in schizophrenia, World J Biol Psychiatry 10:697-701, 2009.
97. Skottun BC, Skoyles JR, Are masking abnormalities in schizophrenia specific to type- B masking? World J Biol Psychiatry 10:798-808, 2009.
98. Skottun BC, Skoyles JR, Vernier acuity as a test of magnocellular sensitivity, Neuro- Ophthalmology 34:82-87, 2010.
99. Skottun BC, Skoyles JR, Backward masking as a test of magnocellular sensitivity, Neuro-Ophthalmology 34:342-346, 2010.
100. Skottun BC, Skoyles JR, On identifying magnocellular and parvocellular responses on the basis of contrast-response functions, Schizophr Bull 37:23-26, 2010.
101. Slaghuis WL, Spatio-temporal luminance contrast sensitivity and visual backward masking in schizophrenia, Exp Brain Res 156:196-211, 2004. (Pubitemid 38626477)
102. SlaghuisWL, Bakker VJ, Forward and backward visual masking of contour by light in positive- and negative-symptom schizophrenia, J Abnorm Psychol 104:41-54, 1995.
103. Slaghuis WL, Curran CE, Spatial frequency masking in positive- and negativesymptom schizophrenia, J Abnorm Psychol 108:42-50, 1999. (Pubitemid 29108308)
104. Surguladze SA, Chkonia ED, Kezeli AR, Roinishvili MO, Stahl D, David AS, The McCollough effect and facial emotion discrimination in patients with schizophrenia and their unaffected relatives, Schizophrenia Bull in press, 2011.
105. Suslow T, Arolt V, Paranoid schizophrenia: Non-specificity of neuropsychological vulnerability markers, Psychiatry Res 72:103-114, 1997. (Pubitemid 27425452)
106. Tse P, Martinez-Conde S, Schlegel AA, Macknik SL, Visibility, visual awareness, and visual masking of simple unattended targets are confined to areas in the occipital cortex beyond human V1/V2, Proc Natl Acad Sci USA 102:17178-17183, 2005. (Pubitemid 41692703)
107. Vidyasagar TR, Kulikowski JJ, Lipnicki DM, Dreher B, Convergence of parvocellular and magnocellular channels in the primary visual cortex of the macaque, Eur J Neurosci 16:945-956, 2002. (Pubitemid 35463586)
108. Weiner RU, Opler LA, Kay SR, Merriam AE, Papouchis N, Visual information processing in positive, mixed, and negative schizophrenic syndromes, J Nerv Mental Disease 178:616-626, 1990. (Pubitemid 20378881)
109. Weisstein N, Ozog G, Szoc R, A comparison and elaboration of two models of metacontrast, Psychol Rev 82:325-343, 1975.
110. White AJ, Solomon SG, Martin PR, Spatial properties of koniocellular cells in the lateral geniculate nucleus of the marmoset Callithrix jacchus, J Physiol (Lond) 533:519-535, 2001. (Pubitemid 32520005)
111. Wynn JK, Light GA, Breitmeyer B, Nuechterlein K, Green MF, Event-related gamma activity in schizophrenia patients during a visual backward-masking task, Am J Psychiatry 162:2330-2336, 2005. (Pubitemid 41740212)