Identifying mRNAs Bound by Human RBMY protein in the testis

Journal of Reproduction and Development

Volumn 57, Issue 1, 2011, Pages 107-112

  Zeng, Mei ^a,b   Liang, Suhua ^a,b   Zhao, Shaozhi ^a   Liu, Yanyan ^a   Sun, Huaqin ^a   Zhang, Sizhong ^a   Ma, Yongxin ^a  

^a SICHUAN UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Nek10; Rbmy gene; RNA binding protein; SNAAP technique; Spermatogenesis

Indexed keywords

HYBRID PROTEIN; MESSENGER RNA; NEK10 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; RBMY1A1 PROTEIN, HUMAN; RNA BINDING PROTEIN;

ALTERNATIVE RNA SPLICING; ARTICLE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALE; METABOLISM; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOGENESIS; TESTIS;

ALTERNATIVE SPLICING; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION PROFILING; HUMANS; MALE; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SPERMATOGENESIS; TESTIS;

EID: 79952927726     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.10-092N     Document Type: Article

References (37)

1. Willison K, Ashworth A. Mammalian spermatogenic gene expression. Trends Genet 1987; 3: 351-355.
2. Hecht NB. The making of a spermatozoon: a molecular perspective. Dev Genet 1995; 16: 95-103.
3. Sassone-Corsi P. Transcriptional checkpoints determining the fate of male germ cell. Cell 1997; 88: 163-166.
4. Eddy EM, O'Brien DA. Gene expression during mammalian meiosis. Curr Top Dev Biol 1998; 37: 141-200.
5. Tiepolo L, Zuffardi O. Localisation of factors controlling spermatogenesis in the non-fluorecent portion of the human Y chromosome long arm. Hum Genet 1976; 34: 119-124.
6. Ma K, Sharkey A, Bichmore WA, Hill RE, Prosser EJ, Speed RM. A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis. Cell 1993; 75: 1287-1295.
7. Chai NN, Zhou HY, Hernandez J, Najmabadi H, Bhasin S, Yen PH. Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene. Genomics 1998; 49: 283-289.
8. Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature 2003; 423: 825-837.
9. Delbridge ML, Disteche CM, Graves JAM, Lingenfelte PA. The candidate spermato-genesis gene RBMY has a homologue on the human X chromosome. Nat Genet 1999; 22: 223-224.
10. Ehrmann I, Dalgliesh C, Tsaousi A, Paronetto MP, Heinrich B, Kist R. Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse. Hum Mol Genet 2008; 17: 2803-2818.
11. Elliott DJ, Ma K, Kerr SM, Thakrar R, Speed R, Chandley AC. An RBM homologue maps to the mouse Y chromosome and is expressed in germ cell. Hum Mol Genet 1996; 5: 869-874.
12. Delbridge ML, Harry JL, Toder R, Ma K, Chandley AC, Graves JAM. A human candidate spermatogenesis gene, RBM1, is conserved and amplified on the marsupial Y chromosome. Nat Genet 1997; 15: 131-136.
13. Mahadevaiah SK, Odorisio T, Elliott DJ, Rattigan A, Szot M, Laval SH. Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities. Hum Mol Genet 1998; 7: 715-727.
14. Jungmin L, Jinpyo H, Euisu K, Kyungjin K, Soo WK. Developmental stage-specific expression of RBM suggests its involvement in early phase of spematogenesis. Mol Hum Reprod 2004; 10: 259-264.
15. Elliott DJ. The role of potential splicing factors including RBMY, RBMX, hnRNPG-T and STAR proteins in spermatogenesis. Int J Androl 2004; 27: 328-334.
16. Bourgeois CF, Lejeune F, Stévenin J. Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of premessenger RNA. Prog Nucleic Acid Res Mol Bio 2004; 78: 37-88.
17. Elliott DJ, Bourgeois CF, Klink A, Stevenin J, Cooke HJA. Mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. Proc Nat Acad Sci USA 2000; 97: 5717-5722.
18. Trifillis P, Kiledjian M, Day N. Finding the right RNA: identification of cellular mRNA substrates for RNA-binding proteins. RNA 1999; 5: 1071-1082.
19. Paronetto MP, Achsel T, Massiello A, Chalfant CE, Sette C. The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. J Cell Biol 2007; 7: 929-939.
20. Jiao X, Triffilis P, Kiledjian M. Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein. Biol Reprod 2002; 66: 475-485.
21. King PH. RNA-binding analyses of Huc and HuD with the VEGF and c-myc 3-untranslated regions using a novel ELISA-based assay. Nucleic Acids Res 2000; 28: E20.
22. Mei Z, Sun HQ, Chen S, Xinyang W, Yuan Y, Yunqiang L. Identification of target messenger RNA substrates for mouse RBMY. Mol Hum Reprod 2008; 14: 331-336.
23. Yang F, Eckardt S, Leu NA, McLaughlin KJ, Wang PJ. Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis. J Cell Biol 2008; 180: 673-679.
24. Adelman CA, Petrini JHJ. ZIP4H (TEX11) Deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. Plos Genet 2008; 4: e1000042.
25. Maruyama O, Nishimor H, Kataqiri T, Miki Y, Ueno A, Nakamura Y. Cloning of TCFL5 encoding a novel human basic helix-loop-helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage. Cytogenet Cell Genet 1998; 82: 41-45.
26. Siep M, Sleddens-Linkels E, Mulders S, Van EH, Wassenaar E, Van CWA. Basic helix-loop-helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis. Nucleic Acids Res 2004; 32: 6425-6436.
27. Greenbaum MP, Yan W, Wu MH. TEX14 is essential for intercellular bridges and fertility in male mice. Proc Nat Acad Sci USA 2006; 103: 4982-4987.
28. Maniatis T, Tasic B. Alternative pre-mRNA splicing and proteome expansion in metazoan. Nature 2002; 418: 236-243.
29. Black DL. Mechanism of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003; 72: 291-336.
30. Stetefeld J, Ruegg MA. Structural and functional diversity generated by alternative mRNA splicing. Trends Biochem Sci 2005; 30: 515-521.
31. Boue S, Letunic I, Bork P. Alternative splicing and evolution. Bioessays 2003; 25: 1031-1034.
32. Kan Z, Garrett-Engele PW, Johnson JM, Castle JC. Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles. Nucleic Acids Res 2005; 33: 5659-5666.
33. Joan R, Aaron G, Jennifer C, Joseph A. Active Nerc2 protein kinase concentrates at centrosomes early in mitosis and is necessary for proper spindle assembly. Mol Bio Cell 2005; 16: 4827-4840.
34. Natacha D, Cyril FB, Fabrice L, Yilei L, Ingrid EE, David JE, James S. Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-β. J Cell Sci 2010; 123: 40-50.
35. Hecht NB. Molecular mechanisms of male germ cell differentiation. BioEssays 1998; 20: 555-561.
36. Grizzi F, Chiriva IM, Franceschini B, Hemonat PL, Soda G, Lim SH. Immunolocalization of sperm protein 17 in human testis and ejaculated spermatozoa. J Histochem Cytochem 2003; 51: 1245-1248.
37. Skrisovska L, Bourgeois CF, Stefl R, Grellscheid SN, Kister L, Wenter P. The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction. EMBO Reports 2007; 8: 372-379.