Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis

Journal of Ocular Pharmacology and Therapeutics

Volumn 27, Issue 2, 2011, Pages 187-195

  Bohets, Hilde ^a   McGowan, Claude ^b   Mannens, Geert ^a   Schroeder, Nathalie ^a   Edwards Swanson, Kimberly ^b   Shapiro, Aron ^c  

^a JohnsonandJohnson PRD   (Belgium)

^b JohnsonandJohnson Consumer Products US   (United States)

^c Ora Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; ALCAFTADINE; ALPHA NAPHTHOFLAVONE; ANILINE; CAFFEINE; CARBOXYLIC ACID; CHLORZOXAZONE; COUMARIN; CYCLOSPORIN; DEBRISOQUINE; DRUG METABOLITE; FURAFYLLINE; GESTODENE; LAURIC ACID; MEPHENYTOIN; PHENACETIN; PHENYTOIN; PLACEBO; QUINIDINE; SULFAPHENAZOLE; TOLBUTAMIDE; TROLEANDOMYCIN;

ADULT; ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMOSIS; CONJUNCTIVAL HYPEREMIA; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; DRUG HYDROXYLATION; DRUG INHIBITION; DRUG METABOLISM; DRUG OXIDATION; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; ENZYME ACTIVITY; EQUILIBRIUM DIALYSIS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIMIT OF DETECTION; LIVER MICROSOME; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PROTEIN BINDING; PROTON NUCLEAR MAGNETIC RESONANCE; RANDOMIZED CONTROLLED TRIAL; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT RESPONSE; X RAY DIFFRACTION;

ADOLESCENT; ADULT; BENZAZEPINES; CHEMISTRY, PHARMACEUTICAL; CONJUNCTIVITIS, ALLERGIC; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HISTAMINE ANTAGONISTS; HUMANS; IMIDAZOLES; MALE; MICROSOMES, LIVER; MIDDLE AGED; PROTEIN BINDING;

EID: 79952925214     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2010.0153     Document Type: Article

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