The tramadol metabolite O-desmethyl tramadol inhibits substance P-receptor functions expressed in Xenopus oocytes

Journal of Pharmacological Sciences

Volumn 115, Issue 3, 2011, Pages 421-424

  Minami, Kouichiro ^a,b   Yokoyama, Toru ^a,b   Ogata, Junichi ^a   Uezono, Yasuhito ^b  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

O desmethyl tramadol (ODT); Substance P; Tramadol

Indexed keywords

BISINDOLYLMALEIMIDE; CALCIUM ION; CHLORIDE; O NORTRAMADOL; PROTEIN KINASE C; SUBSTANCE P RECEPTOR;

ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; FEMALE; INHIBITION KINETICS; NONHUMAN; OOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; XENOPUS;

EID: 79952800078     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10313SC     Document Type: Article

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