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Volumn 12, Issue 4, 2010, Pages 5-11

Pharmacology of "atypicality" of antipsychotic drugs: Status and perspective

Author keywords

5 HT1A receptors; Antipsychotic; D2 receptors; Schizophrenia

Indexed keywords

ADOPRAZINE; ARIPIPRAZOLE; ASENAPINE; ATYPICAL ANTIPSYCHOTIC AGENT; BIFEPRUNOX; CARIPRAZINE; CHLORPROMAZINE; CLOZAPINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; F 15063; HALOPERIDOL; LURASIDONE; OLANZAPINE; PALIPERIDONE; PEROSPIRONE; PF 217830; QUETIAPINE; RISPERIDONE; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A ANTAGONIST; SERTINDOLE; SSR 181507; UNCLASSIFIED DRUG; ZIPRASIDONE;

EID: 79952787886     PISSN: 15092046     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (34)
  • 1
    • 19844380572 scopus 로고    scopus 로고
    • Size of burden of schizophrenia and psychotic disorders
    • DOI 10.1016/j.euroneuro.2005.04.009, PII S0924977X05000726, Size and Burden of Mental Disorders in Europe
    • Rossler W, et al. Size of burden of schizophrenia and psychotic disorders. Eur Neuropsychopharmacol. 2005; 15(4): 399-409. (Pubitemid 40943544)
    • (2005) European Neuropsychopharmacology , vol.15 , Issue.4 , pp. 399-409
    • Rossler, W.1    Joachim, S.H.2    Van Os, J.3    Riecher-Rossler, A.4
  • 2
    • 50349096587 scopus 로고    scopus 로고
    • In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
    • Meltzer HY, and Huang M. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. Prog Brain Res. 2008; 172: 177-97.
    • (2008) Prog Brain Res , vol.172 , pp. 177-197
    • Meltzer, H.Y.1    Huang, M.2
  • 3
    • 33745341905 scopus 로고    scopus 로고
    • Non-neurological side-effects of antipsychotic drugs
    • Hirsch SR, Weinberger D. editors Oxford: Blackwell Publishing
    • Goff DC, and Shader RI. Non-neurological side-effects of antipsychotic drugs. In: Hirsch SR, Weinberger D. editors. Schizophrenia. Oxford: Blackwell Publishing; 2003. 573-588.
    • (2003) Schizophrenia , pp. 573-588
    • Goff, D.C.1    Shader, R.I.2
  • 4
    • 0342980323 scopus 로고    scopus 로고
    • Relationship between dopaminergic and serotonergic neuronal activity in the frontal cortex and the action of typical and atypical antipsychotic drugs
    • Ichikawa J, Meltzer HY. Relationship between dopaminergic and serotonergic neuronal activity in the frontal cortex and the action of typical and atypical antipsychotic drugs. Eur Arch Psychiatry Clin Neurosci. 1999; 249(Suppl 4): 90-8.
    • (1999) Eur Arch Psychiatry Clin Neurosci , vol.249 , Issue.SUPPL. 4 , pp. 90-98
    • Ichikawa, J.1    Meltzer, H.Y.2
  • 6
    • 50349085334 scopus 로고    scopus 로고
    • Role of serotonin and dopamine receptor binding in antipsychotic efficacy
    • Richtand NM, et al. Role of serotonin and dopamine receptor binding in antipsychotic efficacy. Prog Brain Res. 2008; 172: 155-75.
    • (2008) Prog Brain Res , vol.172 , pp. 155-175
    • Richtand, N.M.1
  • 7
    • 4644271084 scopus 로고    scopus 로고
    • Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
    • Roth BL, Sheffler DJ, Kroeze WK. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov. 2004; 3(4): 353-9. (Pubitemid 38499762)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.4 , pp. 353-359
    • Roth, B.L.1    Sheffer, D.J.2    Kroeze, W.K.3
  • 8
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms
    • Reynolds GP, Kirk SL. Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms. Pharmacol Ther. 2010; 125(1): 169-79.
    • (2010) Pharmacol Ther , vol.125 , Issue.1 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 9
    • 0038618835 scopus 로고    scopus 로고
    • Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis
    • Tamminga CA, Carlsson A. Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis. Curr Drug Targets CNS Neurol Disord. 2002; 1(2): 141-7.
    • (2002) Curr Drug Targets CNS Neurol Disord , vol.1 , Issue.2 , pp. 141-147
    • Tamminga, C.A.1    Carlsson, A.2
  • 10
    • 34347336444 scopus 로고    scopus 로고
    • Neuropharmacological profile of bifeprunox: Merits and limitations in comparison with other third-generation antipsychotics
    • Newman-Tancredi A, Cussac D, Depoortere R. Neuropharmacological profile of bifeprunox: merits and limitations in comparison with other third-generation antipsychotics. Curr Opin Investig Drugs. 2007; 8(7): 539-54. (Pubitemid 47016322)
    • (2007) Current Opinion in Investigational Drugs , vol.8 , Issue.7 , pp. 539-554
    • Newman-Tancredi, A.1    Cussac, D.2    Depoortere, R.3
  • 11
    • 77954122304 scopus 로고    scopus 로고
    • The importance of 5-HT1A receptor agonism in antipsychotic drug action: Rationale and perspectives
    • Newman-Tancredi A. The importance of 5-HT1A receptor agonism in antipsychotic drug action: rationale and perspectives. Curr Opin Investig Drugs. 2010; 11(7): 802-12.
    • (2010) Curr Opin Investig Drugs , vol.11 , Issue.7 , pp. 802-812
    • Newman-Tancredi, A.1
  • 12
    • 25644452796 scopus 로고    scopus 로고
    • Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: Frontocortical dopamine and hippocampal serotonin release in rat brain
    • Assie MB, et al. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. J Pharmacol Exp Ther. 2005; 315(1): 265-72.
    • (2005) J Pharmacol Exp Ther , vol.315 , Issue.1 , pp. 265-272
    • Assie, M.B.1
  • 13
    • 0030694503 scopus 로고    scopus 로고
    • Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation
    • Rollema H, et al. Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Eur J Pharmacol. 1997; 338(2): 3-5.
    • (1997) Eur J Pharmacol , vol.338 , Issue.2 , pp. 3-5
    • Rollema, H.1
  • 14
    • 0030610492 scopus 로고    scopus 로고
    • 3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia
    • DOI 10.1016/S0197-0186(96)00124-6, PII S0197018696001246
    • Burnet PW, Eastwood SL, Harrison PJ. [3H]WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with [3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia. Neurochem Int. 1997; 30(6): 565-74. (Pubitemid 27187227)
    • (1997) Neurochemistry International , vol.30 , Issue.6 , pp. 565-574
    • Burnet, P.W.J.1    Eastwood, S.L.2    Harrison, P.J.3
  • 15
    • 0036270010 scopus 로고    scopus 로고
    • Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635
    • Tauscher J, et al. Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635. Arch Gen Psychiatry. 2002; 59(6): 514-20.
    • (2002) Arch Gen Psychiatry , vol.59 , Issue.6 , pp. 514-520
    • Tauscher, J.1
  • 16
    • 0142102450 scopus 로고    scopus 로고
    • Serotonin 5-HT1A receptors might control the output of cortical glutamatergic neurons in rat cingulate cortex
    • DOI 10.1016/S0006-8993(03)03352-3
    • Czyrak A, et al. Serotonin 5-HT1A receptors might control the output of cortical glutamatergic neurons in rat cingulate cortex. Brain Res. 2003; 989(1): 42-51. (Pubitemid 37281400)
    • (2003) Brain Research , vol.989 , Issue.1 , pp. 42-51
    • Czyrak, A.1    Czepiel, K.2    Mackowiak, M.3    Chocyk, A.4    Wedzony, K.5
  • 17
    • 0343742652 scopus 로고    scopus 로고
    • Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT(1A) serotonin receptors in the rat brain
    • DOI 10.1016/S0006-8993(97)00159-5, PII S0006899397001595
    • Wedzony K, et al. Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain. Brain Res. 1997; 756(1-2): 84-91. (Pubitemid 27241611)
    • (1997) Brain Research , vol.756 , Issue.1-2 , pp. 84-91
    • Wedzony, K.1    Mackowiak, M.2    Czyrak, A.3    Fijal, K.4    Michalska, B.5
  • 18
    • 33645107480 scopus 로고    scopus 로고
    • The 5-HT(1A) receptor agonist 8-OH-DPAT prevents prefrontocortical glutamate and serotonin release in response to blockade of cortical NMDA receptors
    • Calcagno E, Carti M, Invernizzi RW. The 5-HT(1A) receptor agonist 8-OH-DPAT prevents prefrontocortical glutamate and serotonin release in response to blockade of cortical NMDA receptors. J Neurochem. 2006; 96(3): 853-60.
    • (2006) J Neurochem , vol.96 , Issue.3 , pp. 853-860
    • Calcagno, E.1    Carti, M.2    Invernizzi, R.W.3
  • 19
    • 0023920285 scopus 로고
    • 8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis
    • Invernizzi RW, Cervo L, Samanin R. 8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis. Neuropharmacology. 1988; 27(5): 515-8.
    • (1988) Neuropharmacology , vol.27 , Issue.5 , pp. 515-518
    • Invernizzi, R.W.1    Cervo, L.2    Samanin, R.3
  • 20
    • 21644447088 scopus 로고    scopus 로고
    • 1A receptor activation in attenuation of catalepsy induction in rats
    • DOI 10.1016/j.neuropharm.2005.02.005, PII S002839080500081X
    • Kleven MS, et al. Novel antipsychotic agents with 5-HT(1A) agonist properties: role of 5-HT(1 A) receptor activation in attenuation of catalepsy induction in rats. Neuropharmacology. 2005; 49(2): 135-43. (Pubitemid 40933752)
    • (2005) Neuropharmacology , vol.49 , Issue.2 , pp. 135-143
    • Kleven, M.S.1    Barret-Grevoz, C.2    Slot, L.B.3    Newman-Tancredi, A.4
  • 21
    • 0037174823 scopus 로고    scopus 로고
    • 1A receptor activation and anti-cataleptic effects: High-efficacy agonists maximally inhibit haloperidol-induced catalepsy
    • DOI 10.1016/S0014-2999(02)02430-5, PII S0014299902024305
    • Prinssen EP, Colpaert FC, Koek W. 5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy. Eur J Pharmacol. 2002; 453(2-3): 217-21. (Pubitemid 35223513)
    • (2002) European Journal of Pharmacology , vol.453 , Issue.2-3 , pp. 217-221
    • Prinssen, E.P.M.1    Colpaert, F.C.2    Koek, W.3
  • 22
    • 38549162242 scopus 로고    scopus 로고
    • Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells
    • Heusler P, et al. Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells. Eur J Pharmacol. 2008; 581(1-2): 37-46.
    • (2008) Eur J Pharmacol , vol.581 , Issue.1-2 , pp. 37-46
    • Heusler, P.1
  • 23
    • 22344431960 scopus 로고    scopus 로고
    • Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: Affinity, efficacy and potential implications for treatment of schizophrenia
    • DOI 10.1017/S1461145704005000
    • Newman-Tancredi A, et al. Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia. Int J Neuropsychopharmacol. 2005; 8(3): 341-56. (Pubitemid 41002489)
    • (2005) International Journal of Neuropsychopharmacology , vol.8 , Issue.3 , pp. 341-356
    • Newman-Tancredi, A.1    Assie, M.-B.2    Leduc, N.3    Ormiere, A.-M.4    Danty, N.5    Cosi, C.6
  • 24
    • 0032466835 scopus 로고    scopus 로고
    • S16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-yloxy)-ethyl]- pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: II. Functional profile in comparison to clozapine and haloperidol
    • Millan MJ, et al. S16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: II. Functional profile in comparison to clozapine and haloperidol. J Pharmacol Exp Ther. 1998; 286(3): 1356-73.
    • (1998) J Pharmacol Exp Ther , vol.286 , Issue.3 , pp. 1356-1373
    • Millan, M.J.1
  • 26
    • 42749092601 scopus 로고    scopus 로고
    • Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: Role of serotonin 5-HT1A receptors
    • Hagiwara H, et al. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors. Eur Neuropsychopharmacol. 2008; 18(6): 448-54.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.6 , pp. 448-454
    • Hagiwara, H.1
  • 27
    • 59449096993 scopus 로고    scopus 로고
    • Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors
    • Nagai T, et al. Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors. Psychopharmacology. 2009; 202(1-3): 315-28.
    • (2009) Psychopharmacology , vol.202 , Issue.1-3 , pp. 315-328
    • Nagai, T.1
  • 28
    • 52949139104 scopus 로고    scopus 로고
    • Does stimulation of 5-HT(1A) receptors improve cognition in schizophrenia?
    • Meltzer HY, Sumiyoshi T. Does stimulation of 5-HT(1A) receptors improve cognition in schizophrenia? Behav Brain Res. 2008; 195(1): 98-102.
    • (2008) Behav Brain Res , vol.195 , Issue.1 , pp. 98-102
    • Meltzer, H.Y.1    Sumiyoshi, T.2
  • 29
    • 34248572635 scopus 로고    scopus 로고
    • Optimisation of anti-psychotic therapeutics: A balancing act?
    • Lawrence AJ. Optimisation of anti-psychotic therapeutics: a balancing act? Br J Pharmacol. 2007; 151(2): 161-2.
    • (2007) Br J Pharmacol , vol.151 , Issue.2 , pp. 161-162
    • Lawrence, A.J.1
  • 30
    • 27144443377 scopus 로고    scopus 로고
    • Effects of novel antipsychotics with mixed D(2) antagonist/5-HT(1A) agonist properties on PCP-induced social interaction deficits in the rat
    • Bruins Slot LA, Kleven MS, Newman-Tancredi A. Effects of novel antipsychotics with mixed D(2) antagonist/5-HT(1A) agonist properties on PCP-induced social interaction deficits in the rat. Neuropharmacology. 2005; 49(7): 996-1006.
    • (2005) Neuropharmacology , vol.49 , Issue.7 , pp. 996-1006
    • Bruins Slot, L.A.1    Kleven, M.S.2    Newman-Tancredi, A.3
  • 33
    • 62149130436 scopus 로고    scopus 로고
    • F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: Influence on neuronal firing and neurotransmitter release
    • Assie MB, et al. F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: influence on neuronal firing and neurotransmitter release. Eur J Pharmacol. 2009; 607(1-3): 74-83.
    • (2009) Eur J Pharmacol , vol.607 , Issue.1-3 , pp. 74-83
    • Assie, M.B.1
  • 34
    • 43249099229 scopus 로고    scopus 로고
    • Improvement of phencyclidine-induced social behaviour deficits in rats: Involvement of 5-HT1A receptors
    • Snigdha S, Neill JC. Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors. Behav Brain Res. 2008; 191(1): 26-31.
    • (2008) Behav Brain Res , vol.191 , Issue.1 , pp. 26-31
    • Snigdha, S.1    Neill, J.C.2


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