Loss of anti-proliferative effect of all-trans retinoic acid in advanced stage of breast carcinogenesis

Anticancer Research

Volumn 29, Issue 8, 2009, Pages 2899-2904

  Eun, Hyun Ahn ^a   Chang, Chia Cheng ^c   Talmage, David A ^a,b,d  

^a Chung Ang University   (South Korea)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d STONY BROOK UNIVERSITY   (United States)

Author keywords

All trans retinoic acid; Breast cancer; c erbB2 neu; Proliferation; Tyrosine phosphorylation

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROTEIN P185; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; TOCORETINATE;

ADVANCED CANCER; ARTICLE; BREAST CARCINOGENESIS; CANCER INHIBITION; CANCER STAGING; CELL IMMORTALIZATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG EFFICACY; GENE EXPRESSION; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; ONCOGENE NEU; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINOIC ACID RECEPTOR ELEMENT; SURVIVAL RATE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; LUCIFERASES; RECEPTOR, ERBB-2; RECEPTORS, RETINOIC ACID; REGULATORY ELEMENTS, TRANSCRIPTIONAL; TRANSCRIPTIONAL ACTIVATION; TRETINOIN;

EID: 68549120847     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Niles RM: Recent advances in the use of vitamin A (retinoids) in the prevention and treatment of cancer. Nutrition 16: 1084-1090, 2000.
2. Lotan R: Retinoids in cancer chemoprevention. FASEB J 10: 1031-1039, 1996.
3. Cho Y, Tighe AP and Talmage DA: Retinoic acid induced growth arrest of human breast carcinoma cells is accompanied by induction of protein kinase C α expression. J Cell Physiol 172: 306-313, 1997.
4. Kao CY, Nomata K, Oakley CS, Welsch CW and Chang CC: Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and responses to SV40 transfection. Carcinogenesis 16: 531-538, 1995.
5. c-erbB2/neu in tumorigenicity induced by X-rays and the neu oncogene in human breast ephithelial cells. Mol Carcinogen 21: 225-233, 1998. (Pubitemid 28208743)
6. Sun W, Kang KS, Morita I, Trosko JE and Chang CC: High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization. Cancer Res 59: 6118-6123, 1999. (Pubitemid 30035631)
7. Chang CC, Sun W, Cruz A, Satoh M, Tai MH and Trosko JE: A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis. Radiation Res 155: 201-207, 2001. (Pubitemid 33723539)
8. Chang CC: Recent translational research: stem cells as the root of breast cancer. Breast Cancer Res 8: 103, 2006.
9. Ahn EH and Schroeder JJ: Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells. Exp Biol Med 27: 345-353, 2002.
10. Ahn EH, Chang CC and Schroeder JJ: Evaluation of sphinganine and sphingosine as breast cancer chemotherapeutic and chemopreventive agents. Exp Biol Med 231: 1664-1672, 2006. (Pubitemid 44808371)
11. Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A and McGuire WL: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182, 1987.
12. Menard S, Pupa SM, Campiglio M and Tagliabue E: Biologic and therapeutic role of HER2 in cancer. Oncogene 22: 6570-6578, 2003. (Pubitemid 37372337)
13. Yu D and Hung MC: Role of erbB2 in breast cancer chemosensitivity. Bio Essays 22: 673-680, 2000. (Pubitemid 30457959)
14. Tari AM, Lim SJ, Hung MC, Esteva FJ and Lopez-Berestein G: Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells. Oncogene 21: 5224-5232, 2002.
15. Skoog L, Humla S, Axelsson M, Frost M, Norman A, Nordenskjold B and Wallgren A: Estrogen receptor levels and survival of breast cancer patients: A study on patients participating in randomized trials of adjuvant therapy. Acta Oncol 26: 95-100, 1987. (Pubitemid 17144041)
16. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO and Botstein D: Molecular portraits of human breast tumours. Nature 406: 747-752, 2000. (Pubitemid 30671230)
17. Gruvberger S, Ringner M, Chen Y, Panavally S, Saal LH, Borg Å, Ferno M, Peterson C and Meltzer PS: Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res 61: 5979-5984, 2001. (Pubitemid 32762524)
18. West M, Blanchette C, Dressman H, Huang E, Ishida S, Spang R, Zuzan H, Olson JA Jr, Marks JR and Nevins JR: Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci USA 98: 11462-11467, 2001. (Pubitemid 32928751)
19. Keshgegian AA: ErbB-2 oncoprotein overexpression in breast carcinoma: inverse correlation with biochemically- and immunohistochemically-determined hormone receptors. Breast Cancer Res Treat 35: 201-210, 1995.
20. Konecny G, Pauletti G, Pegram M, Untch M, Dandekar S, Aguilar Z, Wilson C, Rong HM, Bauerfeind I, Felber M, Wang HJ, Beryt M, Seshadri R, Hepp H and Slamon DJ: Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer. J Natl Cancer Inst 95: 142-153, 2003. (Pubitemid 36193263)
21. Ahr A, Holtrich U, Solbach C, Scharl A, Strebhardt K, Karn T and Kaufmann M: Molecular classification of breast cancer patients by gene expression profiling. J Pathology 195: 312-320, 2001.
22. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Eystein LP and Borresen-Dale AL: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98: 10869-10874, 2001. (Pubitemid 32878711)
23. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL and Botstein D: Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100: 8418-8423, 2003. (Pubitemid 36842560)
24. West RB, Nuyten DS, Subramanian S, Nielsen TO, Corless CL, Rubin BP, Montgomery K, Zhu S, Patel R, Hernandez-Boussard T, Goldblum JR, Brown PO, van de Vijver M and van de Rijn M: Determination of stromal signatures in breast carcinoma. PLoS Biology 3: e187, 2005.
25. Iwao K, Matoba R, Ueno N, Ando A, Miyoshi Y, Matsubara K, Noguchi S and Kato K: Molecular classification of primary breast tumors possessing distinct prognostic properties. Hum Mol Gen 11: 199-206, 2002. (Pubitemid 34157012)
26. van't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R and Friend SH: Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536, 2002.
27. Dressman MA, Baras A, Malinowski R, Alvis LB, Kwon I, Walz TM and Polymeropoulos MH: Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer. Cancer Res 63: 2194-2199, 2003. (Pubitemid 36538626)
28. Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL and Liu ET: Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 100: 10393-11039, 2003. (Pubitemid 37071889)
29. Sotiriou C, Wirapati P, Loi S, Harris A, Fox S, Smeds J, Nordgren H, Farmer P, Praz V, Haibe-Kains B, Desmedt C, Larsimont D, Cardoso F, Peterse H, Nuyten D, Buyse M, Van de Vijver MJ, Bergh J, Piccart M and Delorenzi ML: Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 98: 262-272, 2006. (Pubitemid 43264710)
30. Bertucci F, Borie N, Ginestier C, Groulet A, Charafe-Jauffret E, Adélaïde J, Geneix J, Bachelart L, Finetti P, Koki A, Hermitte F, Hassoun J, Debono S, Viens P, Fert V, Jacquemier J and Birnbaum D: Identification and validation of an ERBB2 gene expression signature in breast cancers. Oncogene 23: 2564-2575, 2004. (Pubitemid 38520754)
31. Bieche I, Lerebours F, Tozlu S, Espie M, Marty M and Lidereau R: Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature. Clinical Cancer Res 10: 6789-6795, 2004. (Pubitemid 39383027)
32. Gruvberger-Saal SK, Eden P, Ringner M, Baldetorp B, Chebil G, Borg A, Ferno M, Peterson C and Meltzer PS: Predicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles. Mol Cancer Ther 3: 161-168, 2004. (Pubitemid 39193690)
33. Miller LD, Smeds J, George J, Vega VB, Vergara L, Ploner A, Pawitan Y, Hall P, Klaar S, Liu ET and Bergh J: An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA 102: 13550-13555, 2005. (Pubitemid 41420886)
34. Gruvberger-Saal SK, Cunliffe HE, Carr KM and Hedenfalk IA: Microarrays in breast cancer research and clinical practice - the future lies ahead. Endocrine-rel Cancer 13: 1017-1031, 2006.
35. Bocker W, Moll R, Poremba C, Holland R, Van Diest PJ, Dervan P, Burger H, Wai D, Ina DR, Brandt B, Herbst H, Schmidt A, Lerch MM and Buchwallow IB: Common adult stem Cells in the human breast give rise to glandular and myoepithelial cell lineages: A new cell biological concept. Lab Invest 82: 737-746, 2002. (Pubitemid 34633823)