In-transit Merkel cell carcinoma treated with isolated limb perfusion or isolated limb infusion: A case series of 12 patients

Dermatologic Surgery

Volumn 37, Issue 3, 2011, Pages 357-364

  Zeitouni, Nathalie C ^a   Giordano, Cerrene N ^a   Kane, John M ^b  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORMETHINE; DACTINOMYCIN; GAMMA INTERFERON; MELPHALAN; TUMOR NECROSIS FACTOR ALPHA;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER MORTALITY; CANCER RELAPSE; CASE STUDY; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; ISOLATED LIMB INFUSION; ISOLATED LIMB PERFUSION; LIMB AMPUTATION; MALE; MERKEL CELL TUMOR; METASTASIS; MORBIDITY; PRIORITY JOURNAL; TREATMENT RESPONSE;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS, ALKYLATING; CARCINOMA, MERKEL CELL; CHEMOTHERAPY, CANCER, REGIONAL PERFUSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFUSIONS, INTRA-ARTERIAL; LIMB SALVAGE; LYMPHATIC METASTASIS; MALE; MELPHALAN; MIDDLE AGED; SKIN NEOPLASMS; TREATMENT OUTCOME;

EID: 79952771110     PISSN: 10760512     EISSN: 15244725     Source Type: Journal    
DOI: 10.1111/j.1524-4725.2011.01883.x     Document Type: Article

References (29)

1. Duprat JP, Domingues AL, Coelho EG, et al,. Long-term response of isolated limb perfusion with hyperthermia and chemotherapy for Merkel cell carcinoma. Eur J Surg Oncol 2009; 35: 568-72.
2. Boyer JD, Zitelli JA, Brodland DG, D'Angelo G., Local control of primary Merkel cell carcinoma: review of 45 cases treated with Mohs micrographic surgery with and without adjuvant radiation. J Am Acad Dermatol 2002; 47: 885-92.
3. Allen PJ, Bowne WB, Jaques DP, et al,. Merkel cell carcinoma: prognosis and treatment of patients from a single institution. J Clin Oncol 2005; 23: 2300-9.
4. Lampreave JL, Benard F, Alavi A., PET evaluation of therapeutic limb perfusion in Merkel's cell carcinoma. J Nucl Med 1998; 39: 2087-90. (Pubitemid 29001795)
5. Engels EA, Frisch M, Goedert JJ, et al,. Merkel cell carcinoma and HIV infection. Lancet 2002; 359: 497-8. (Pubitemid 34164301)
6. Heath M, Jaimes N, Lemos B, et al,. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol 2008; 58: 375-81. (Pubitemid 351226308)
7. Feng H, Shuda M, Chang Y, Moore PS., Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science 2008; 319: 1096-100. (Pubitemid 351300792)
8. AJCC Cancer Staging Manual, 7th Edn. New York: Springer, 2010.
9. O'Connor WJ, Roenigk RK, Brodland DG., Merkel cell carcinoma. Comparison of Mohs micrographic surgery and wide excision in eighty-six patients. Dermatol Surg 1997; 23: 929-33. (Pubitemid 27476113)
10. Allen P, Feng Z, Coit D., The surgical management of merkel cell carcinoma. Ann Surg 1998; 229: 97-105.
11. Gupta AS, Heinzman S, Levine EA., Successful treatment of in-transit metastases from Merkel's cell carcinoma with isolated hyperthermic limb perfusion. South Med J 1998; 91: 289-92. (Pubitemid 28227600)
12. Ross MI., Current status of hyperthermic limb perfusion for in-transit melanoma. Int J Hyperthermia 2008; 24: 205-17. (Pubitemid 351517155)
13. Dawson R, Williams OM, Mansel RE., Isolated hyperthermic limb perfusion chemotherapy in Merkel cell tumour: a case report. J R Coll Surg Edinb 1996; 41: 255-6. (Pubitemid 26267812)
14. Ponte P, Moniz JV, Farricha V, Weinholtz JB., Merkel cell carcinoma: an unusual indication for isolated limb perfusion. Dermatol Online J 2008; 14: 6.
15. Thompson JF, Kam PC, Waugh RC, Harman CR., Isolated limb infusion with cytotoxic agents: a simple alternative to isolated limb perfusion. Semin Surg Oncol 1998; 14: 238-47.
16. Bonvalot S, Laplanche A, Lejeune F, et al,. Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better? Ann Oncol 2005; 16: 1061-8.
17. Olieman AF, Lienard D, Eggermont AM., Hyperthermic isolated limb perfusion with tumor necrosis factor alpha, interferon gamma, and melphalan for locally advanced nonmelanoma skin tumors of the extremities. Arch Surg 1999; 134: 303-7. (Pubitemid 29136017)
18. Kroon HM, Lin DY, Kam PC, Thompson JF., Efficacy of repeat isolated limb infusion with melphalan and actinomycin D for recurrent melanoma. Cancer 2009; 115: 1932-40.
19. Albertini JJ, Cruse CW, Rappaport D, et al,. Intraoperative Radiolymphoscintigraphy improves sentinel lymph node identification for patients with melanoma. Ann Surg 1996; 223: 217-24. (Pubitemid 26065217)
20. Feun LG, Savaraj N, Legha SS, et al,. Chemotherapy for metastatic Merkel cell carcinoma. Review of the M.D. Anderson Hospital's experience. Cancer 1988; 62: 683-5.
21. Creech O Jr., Krementz Et, Ryan RF, Winblade JN., Chemotherapy of cancer: regional perfusion utilizing an extracorporeal circuit. Ann Surg 1958; 148: 616-32.
22. Thompson JF, Siebert GA, Anissimov YG, et al,. Microdialysis and response during regional chemotherapy by isolated limb infusion of melphalan for limb malignancies. Br J Cancer 2001; 85: 157-65. (Pubitemid 32700296)
23. Thompson JF, Waugh RC, saw RPM, Kam PCA., Isolated limb infusion with melphalan for recurrent limb melanoma: a simple alternative to isolated limb perfusion. Reg Cancer Treat 1994; 7: 188-92.
24. Beasley GM, Petersen RP, Yoo J, et al,. Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion 1. Ann Surg Oncol 2008; 15: 2195-205.
25. Wood BC, Kleinpeter KP, Levine EA., Treatment of in-transit metastases from Merkel cell carcinoma with isolated hyperthermic limb perfusion. Am Surg 2007; 73: 1291-2. (Pubitemid 351396510)
26. Grandpeix C, Bonvalot S, Petrow P, et al,. [Continued complete remission of Merkel cell carcinoma with in-transit metastasis after treatment with isolated limb perfusion regional chemotherapy]. Ann Dermatol Venereol 2006; 133: 700-3. (Pubitemid 44401077)
27. Kapteijn BAE, Nieweg OE, Liem I, et al,. Localizing the sentinel node in cutaneous melanoma: gamma probe detection versus blue dye. Ann Surg Oncol 1997; 4: 156-60.
28. Klicks RJ, Vrouenraets BC, Nieweg OE, Kroon BB., Vascular complications of isolated limb perfusion. Eur J Surg Oncol 1998; 24: 288-91. (Pubitemid 28403417)
29. Grobmyer SR, Copeland EM III, Hochwald SN., Treatment of in-transit metastases from Merkel cell carcinoma with isolated hyperthermic limb infusion. Am Surg 2008; 74: 1222-3.