H4K20 monomethylation faces the WNT

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 8, 2011, Pages 3097-3098

  Schotta, Gunnar ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BINDING PROTEIN; HISTONE METHYLTRANSFERASE; LYMPHOID ENHANCER FACTOR 1; SETD8 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR H4K20ME1; UNCLASSIFIED DRUG; WNT PROTEIN;

CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRAIN HEK293; CHROMATIN CONDENSATION; CHROMATIN STRUCTURE; EMBRYO DEVELOPMENT; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; HOMEOSTASIS; NOTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN METHYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; METHYLATION; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 79952769276     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1100147108     Document Type: Note

References (15)

1. Li Z, Nie F, Wang S, Li L (2011) Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc Natl Acad Sci USA 108:3116-3123.
2. Sierra J, Yoshida T, Joazeiro CA, Jones KA (2006) The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev 20:586-600. (Pubitemid 43345324)
3. Talasz H, Lindner HH, Sarg B, Helliger W (2005) Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation. J Biol Chem 280:38814-38822. (Pubitemid 43853784)
4. Vakoc CR, Sachdeva MM, Wang H, Blobel GA (2006) Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol 26:9185-9195. (Pubitemid 44904415)
5. Houston SI, et al. (2008) Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability. J Biol Chem 283:19478-19488.
6. Liu W, et al. (2010) PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature 466:508-512.
7. Trojer P, et al. (2007) L3MBTL1, a histone-methylation-dependent chromatin lock. Cell 129:915-928. (Pubitemid 46802701)
8. Pesavento JJ, Yang H, Kelleher NL, Mizzen CA (2008) Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle. Mol Cell Biol 28:468-486.
9. Kalakonda N, et al. (2008) Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1. Oncogene 27:4293-4304. (Pubitemid 352009998)
10. Oda H, et al. (2009) Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol 29:2278-2295.
11. Karachentsev D, Sarma K, Reinberg D, Steward R (2005) PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis. Genes Dev 19:431-435. (Pubitemid 40256274)
12. Sakaguchi A, Steward R (2007) Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster. J Cell Biol 176:155-162. (Pubitemid 46143256)
13. Sun XJ, et al. (2008) Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PLoS One 3:e1499.
14. Brantjes H, Roose J, van de Wetering M, Clevers H (2001) All Tcf HMG box transcription factors interact with Groucho-related co-repressors. Nucleic Acids Res 29:1410-1419. (Pubitemid 32288486)
15. Schotta G, et al. (2008) A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev 22:2048-2061.