CXCR4 expression on activated B cells is downregulated by CD63 and IL-21

Journal of Immunology

Volumn 186, Issue 5, 2011, Pages 2800-2808

  Yoshida, Nobuya ^a,b   Kitayama, Daisuke ^a   Arima, Masafumi ^a   Sakamoto, Akemi ^a   Inamine, Ayako ^a   Watanabe Takano, Haruko ^a   Hatano, Masahiko ^a   Koike, Takao ^b   Tokuhisa, Takeshi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD63 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR KINASE 6; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; PROTEIN BCL 6;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENDOCYTOSIS; FLOW CYTOMETRY; INTERNALIZATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; ANTIGENS, CD; B-LYMPHOCYTE SUBSETS; CELLS, CULTURED; DOWN-REGULATION; ENDOCYTOSIS; ENDOSOMES; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, CXCR4;

EID: 79952757259     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003401     Document Type: Article

References (5)

1. Manz, R. A., A. Thiel, and A. Radbruch. 1997. Lifetime of plasma cells in the bone marrow. Nature 388: 133-134. (Pubitemid 27297440)
2. Han, S., K. Hathcock, B. Zheng, T. B. Kepler, R. Hodes, and G. Kelsoe. 1995. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 155: 556-567.
3. Chtanova, T., S. G. Tangye, R. Newton, N. Frank, M. R. Hodge, M. S. Rolph, and C. R. Mackay. 2004. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173: 68-78.
4. Allen, C. D., K. M. Ansel, C. Low, R. Lesley, H. Tamamura, N. Fujii, and J. G. Cyster. 2004. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat. Immunol. 5: 943-952.
5. Caron, G., S. Le Gallou, T. Lamy, K. Tarte, and T. Fest. 2009. CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells. J. Immunol. 182: 7595-7602.