Patient experiences of serious adverse drug reactions and their attitudes to medicines: A qualitative study of survivors of Stevens-Johnson syndrome and toxic epidermal necrolysis in the UK

Drug Safety

Volumn 34, Issue 4, 2011, Pages 319-328

  Butt, Tehreem F ^a,e   Cox, Anthony R ^b,d   Lewis, Helen ^c   Ferner, Robin E ^a,d  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ASTON UNIVERSITY   (United Kingdom)

^c UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^d CITY HOSPITAL   (United Kingdom)

^e QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Adverse drug reactions; Drug hypersensitivity; Post traumatic stress disorders; Questionnaires; Skin disorders, drug induced; Stevens Johnson syndrome; Toxic epidermal necrolysis.

Indexed keywords

ALLOPURINOL; CEPHALOSPORIN; LAMOTRIGINE; PENICILLIN G; PHENYTOIN; SALAZOSULFAPYRIDINE; TRIMETHOPRIM;

ADULT; ALLERGY; ARTICLE; ATTITUDE TO HEALTH; BURN; CLINICAL ARTICLE; DRUG FATALITY; FEAR; HEALTH BELIEF; HEALTH CARE PERSONNEL; HUMAN; MEDICAL ERROR; PATIENT MONITORING; PERSONAL EXPERIENCE; PRIORITY JOURNAL; PROFESSIONAL KNOWLEDGE; PSYCHOLOGICAL ASPECT; QUALITATIVE RESEARCH; SEMI STRUCTURED INTERVIEW; STEVENS JOHNSON SYNDROME; SURVIVOR; TOXIC EPIDERMAL NECROLYSIS; TRUST;

ADULT; AGED; AGED, 80 AND OVER; EPIDERMAL NECROLYSIS, TOXIC; FEMALE; GREAT BRITAIN; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALE; MIDDLE AGED; QUESTIONNAIRES; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; STEVENS-JOHNSON SYNDROME; YOUNG ADULT;

EID: 79952755573     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.2165/11588460-000000000-00000     Document Type: Article

References (13)

1. Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions a cause for admission to hospital: prospective analysis of 18,820 patients. BMJ 2004; 329: 15-9. (Pubitemid 38869995)
2. French LE. Toxic epidermal necrolysis and Stevens Johnson syndrome: our current understanding. Allergol Int 2006; 55: 9-16.
3. Bastuji-Garin S, Rzany B, Stern RS, et al. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 1993; 129 (1): 92-6. (Pubitemid 23029676)
4. Roujeau JC, Kelly JP, Naldi L, et al. Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med 1995; 333 (24): 1600-7.
5. Roujeau JC, Stern RS. Severe cutaneous adverse reactions to drugs. N Engl J Med 1994; 331: 1272-85. (Pubitemid 24333193)
6. Strauss A, Corbin J. Basics of qualitative research. 2nd ed. London: Sage Publications, 1998.
7. Chung WH, Hung SL, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature 2004; 428: 486.
8. Chave TA, Mortimer NJ, Sladden MJ, et al. Toxic epidermal necrolysis: current evidence, practical management, and future directions. Br J Dermatol 2005; 153: 241-5.
9. Kelemen JJ, Cioffi WG, McManus WF, et al. Burn center care for patients with toxic epidermal necrolysis. J Am Coll Surg 1995; 80: 273-8.
10. Patterson DR, Carrigan L, Questad KA, et al. Post-traumatic stress disorder in hospitalized patients with burns injuries. J Burn Care Rehabil 1990; 11 (3): 181-4.
11. Cuthbertson BH, Hull A, Strachan M, et al. Post traumatic stress disorder after critical illness requiring general intensive care. Intensive Care Med 2004; 30(3): 450-5. (Pubitemid 38375620)
12. Ziebland S, Chapple A, Dumelow C, et al. How the internet affects patients' experience of cancer: a qualitative study. BMJ 2004; 328: 564.
13. Davison KP, Pennebaker JW, Dickerson SS. Who talks? The social psychology of illness support groups. Am Psychol 2000; 55 (2): 205-17