TCR mimic monoclonal antibodies induce apoptosis of tumor cells via immune effector-independent mechanisms

Journal of Immunology

Volumn 186, Issue 5, 2011, Pages 3265-3276

  Verma, Bhavna ^a   Jain, Rinki ^a   Caseltine, Shannon ^b   Rennels, Aaron ^b   Bhattacharya, Raktima ^c   Markiewski, Maciej M ^a   Rawat, Amit ^a   Neethling, Francisca ^b   Bickel, Ulrich ^c   Weidanz, Jon A ^a,b  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Receptor Logic Inc   (United States)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; CYTOCHROME C; HLA ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; STRESS ACTIVATED PROTEIN KINASE; TCR MIMIC MONOCLONAL ANTIBODY RL4B; TCR MIMIC MONOCLONAL ANTIBODY RL6A; UNCLASSIFIED DRUG;

ACUTE MONOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIGEN BINDING; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER INHIBITION; CELL VIABILITY; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; APOPTOSIS; CELL LINE, TUMOR; FEMALE; HLA-A2 ANTIGEN; HUMANS; LEUKEMIA, MONOCYTIC, ACUTE; MAMMARY NEOPLASMS, EXPERIMENTAL; MELANOMA, EXPERIMENTAL; MICE; MICE, NUDE; MOLECULAR MIMICRY; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79952748078     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002376     Document Type: Article

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