Thalassemia and hemoglobinopathies in Southeast Asian newborns: Diagnostic assessment using capillary electrophoresis system

Clinical Biochemistry

Volumn 44, Issue 5-6, 2011, Pages 406-411

  Srivorakun, Hataichanok ^a   Fucharoen, Goonnapa ^a   Changtrakul, Yossombat ^a   Komwilaisak, Patcharee ^b   Fucharoen, Supan ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Capillary electrophoresis; Hemoglobinopathy; Newborns screening; Thalassemia

Indexed keywords

GENOMIC DNA; HEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN A2; HEMOGLOBIN BART; HEMOGLOBIN CONSTANT SPRING; HEMOGLOBIN E; HEMOGLOBIN F; HEMOGLOBIN H; UNCLASSIFIED DRUG;

ALPHA THALASSEMIA; ANALYTICAL EQUIPMENT; ARTICLE; CAPILLARY ELECTROPHORESIS; CLINICAL TRIAL; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; DNA DETERMINATION; GENOTYPE; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBIN DETERMINATION; HEMOGLOBINOPATHY; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN DISEASE; NEWBORN SCREENING; PRIORITY JOURNAL; SOUTHEAST ASIA; THALASSEMIA;

ASIA, SOUTHEASTERN; ELECTROPHORESIS, CAPILLARY; HEMOGLOBINOPATHIES; HUMANS; INFANT, NEWBORN; NEONATAL SCREENING; THALASSEMIA;

EID: 79952741154     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2011.01.006     Document Type: Article

References (18)

1. Weatherall D.J. Thalassemia as a global health problem: recent progress toward its control in the developing countries. Ann. NY Acad. Sci. 2010, 1202:17-23.
2. Fucharoen S., Winichagoon P. Hemoglobinopathies in Southeast Asia. Hemoglobin 1987, 11:65-88.
3. Giordano P.C. Starting neonatal screening for haemoglobinopathies in The Netherlands. J. Clin. Pathol. 2009, 62:18-21.
4. Van Delft P., Lenters E., Bakker-Verweij M., DE Korte M., Baylan U., Harteveld C.L., et al. Evaluating five dedicated automatic devices for haemoglobinopathy diagnostics in multi-ethnic populations. Int. J. Lab. Hematol. 2009, 31:484-495.
5. The Capillarys system. An instruction manual. Sebia Incorporation, Cedex, France, 2007.
6. Mario N., Baudin B., Bruneel A., Janssens J., Vaubourdolle M. Capillary zone electrophoresis for the diagnosis of congenital hemoglobinopathies. Clin. Chem. 1999, 45:285-288.
7. Winichagoon P., Svasti S., Munkongdee T., Chaiya W., Boonmongkol P., Chantrakul N., et al. Rapid diagnosis of thalassemias and other hemoglobinopathies by capillary electrophoresis system. Transl. Res. 2008, 152:178-184.
8. Louahabi A., Philippe M., Lali S., Wallemacq P., Maisin D. Evaluation of a new Sebia kit for analysis of hemoglobin fractions and variants on the Capillarys system. Clin. Chem. Lab. Med. 2006, 44:340-345.
9. Higgins T., Mack M., Khajuria A. Comparison of two methods for the quantification and identification of hemoglobin variants. Clin. Biochem. 2009, 42:701-705.
10. Srivorakun H., Fucharoen G., Sae-ung N., Sanchaisuriya K., Ratanasiri T., Fucharoen S. Analysis of fetal blood using capillary electrophoresis system: a simple method for prenatal diagnosis of severe thalassemia diseases. Eur. J. Haematol. 2009, 83:57-65.
11. Sae-ung N., Fucharoen G., Sanchaisuriya K., Fucharoen S. β0-thalassemia and related disorders in northeast Thailand: a molecular and hematological characterization. Acta Haematol. 2007, 117:78-82.
12. Singsanan S., Fucharoen G., Savongsy O., Sanchaisuruya K., Fucharoen S. Molecular characterization and origins of Hb Constant Spring and Hb Paksé in Southeast Asian populations. Ann. Hematol. 2007, 86:665-669.
13. Fucharoen S., Fucharoen G., Ratanasiri T., Jetsrisuparp A., Fukumaki Y. A simple non-radioactive assay for hemoglobin E gene in prenatal diagnosis. Clin. Chim. Acta 1994, 229:197-203.
14. Siriratmanawong N., Fucharoen G., Sanchaisuriya K., Ratanasiri T., Fucharoen S. Rapid and simultaneous detection of β-thalassemia and β-thalassemia 1 (SEA type) in prenatal diagnosis of complex thalassemia syndrome. Clin. Biochem. 2001, 34:377-380.
15. Mantikou E., Arkesteijin S.G., Beckhoven van J.M., Kerkhoffs J.L., Harteveld C.L., Giordano P.C. A brief review on newborn screening methods for hemoglobinopathies and preliminary results selecting beta thalassemia carriers at birth by quantitative estimation of the HbA fraction. Clin. Biochem. 2009, 42:1780-1785.
16. Trithipsombat J., Sanchaisuriya K., Fucharoen S., Fucharoen G., Siriratmanawong N., Pinmuang-ngam C., et al. Hemoglobin profiles and hematological features of thalassemic newborns: application to screening of α-thalassemia 1 and hemoglobin E. Arch. Pathol. Lab. Med. 2008, 132:1739-1745.
17. Charoenkwan P., Tawephol R., Sirichotiyakul S., Tantiprabha W., Sae-Tung R., Suanta S., et al. Cord blood screening for α-thalassemia and hemoglobin variants by isoelectric focusing in Northern Thai neonates: correlation with genotypes and hematologic parameters. Blood Cells Mol. Dis. 2010, 45:53-57.
18. Boonsa S., Sanchaisuriya K., Fucharoen G., Wiangnon S., Jetsrisuparb A., Fucharoen S. The diverse molecular basis and hematologic features of Hb H and AEBart's diseases in northeast Thailand. Acta Haematol. 2004, 111:149-154.