Rapid diagnosis of thalassemias and other hemoglobinopathies by capillary electrophoresis system

Translational Research

Volumn 152, Issue 4, 2008, Pages 178-184

  Winichagoon, Pranee ^a   Svasti, Saovaros ^a   Munkongdee, Thongperm ^a   Chaiya, Wantana ^a   Boonmongkol, Piatip ^a   Chantrakul, Nawarath ^a   Fucharoen, Suthat ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A; HEMOGLOBIN A2; HEMOGLOBIN E; HEMOGLOBIN F;

ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CLINICAL FEATURE; CONTROLLED STUDY; GENOTYPE; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBINOPATHY; HUMAN; MAJOR CLINICAL STUDY; PHENOTYPE; POPULATION; PRIORITY JOURNAL; THALASSEMIA;

ADULT; ELECTROPHORESIS, CAPILLARY; HEMOGLOBINS, ABNORMAL; HETEROZYGOTE; HUMANS; PHENOTYPE; REPRODUCIBILITY OF RESULTS; THALASSEMIA;

EID: 53749101257     PISSN: 19315244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trsl.2008.08.004     Document Type: Article

References (24)

1. Fucharoen S., and Winichagoon P. Hemoglobinopathies in southeast Asia. Hemoglobin 11 (1987) 65-88
2. 2 reference preparation. Br J Haematol 38 (1978) 573-578
3. Schmidt R.M., Rucknagel D.L., and Necheles T.F. Comparison of methodologies for thalassemia screening by Hb A2 quantitation. J Lab Clin Med 86 (1975) 873-882
4. 2: results from a survey of 10,663 cases. Hemoglobin 1 (1977) 845-860
5. Dubart A., Goossens M., Beuzard Y., et al. Prenatal diagnosis of hemoglobinopathies: comparison of the results obtained by isoelectric focusing of hemoglobins and by chromatography of radioactive globin chains. Blood 56 (1980) 1092-1099
6. Wilson J.B., Headlee M.E., and Huisman T.H. A new high-performance liquid chromatographic procedure for the separation and quantitation of various hemoglobin variants in adults and newborn babies. J Lab Clin Med 102 (1983) 174-186
7. Rogers B.B., Wessels R.A., Ou C.N., and Buffone G.J. High-performance liquid chromatography in the diagnosis of hemoglobinopathies and thalassemias. Report of three cases. Am J Clin Pathol 84 (1985) 671-674
8. 2 and F. J Clin Pathol 46 (1993) 852-856
9. Fucharoen S., Winichagoon P., Wisedpanichkij R., et al. Prenatal and postnatal diagnoses of thalassemias and hemoglobinopathies by HPLC. Clin Chem 44 (1998) 740-748
10. Wang J., Zhou S., Huang W., et al. CE-based analysis of hemoglobin and its applications in clinical analysis. Electrophoresis 27 (2006) 3108-3124
11. Louahabi A., Philippe M., Lali S., Wallemacq P., and Maisin D. Evaluation of a new Sebia kit for analysis of hemoglobin fractions and variants on the Capillarys system. Clin Chem Lab Med 44 (2006) 340-345
12. Winichagoon P., Saechan V., Sripanich R., et al. Prenatal diagnosis of β-thalassaemia by reverse dot-blot hybridization. Prenat Diagn 19 (1999) 428-435
13. Fucharoen S., Fucharoen G., and Fukumaki Y. Simple non-radioactive method for detecting haemoglobin Constant Spring gene. Lancet 335 (1990) 1527
14. Chong S.S., Boehm C.D., Higgs D.R., and Cutting G.R. Single-tube multiplex-PCR screen for common deletional determinants of α-thalassemia. Blood 95 (2000) 360-362
15. Adirojnanon P., and Wasi P. Levels of haemoglobin H and proportions of red cells with inclusion bodies in the two types of haemoglobin H disease. Br J Haematol 46 (1980) 507-509
16. 2 and E. J Lab Clin Med 71 (1968) 85-91
17. Betke K., Marti H.R., and Schlicht I. Estimation of small percentages of foetal haemoglobin. Nature 184 (1959) 1877-1878
18. Fucharoen S., Winichagoon P., Thonglairuam V., Siriboon W., and Sae-Ngow B. Laboratory diagnosis for thalassemia. Ann Acad Med Singapore 18 (1989) 424-430
19. 2 and F. Clin Chem 45 (1999) 237-243
20. Hoyer J.D., and Scheidt R.M. Identification of hemoglobin variants by HPLC. Clin Chem 51 (2005) 1303-1304
21. 2 by the fully automated, high-pressure liquid chromatography Tosoh HLC-723 G7 analyzer. Int J Lab Hematol. In press.
22. 2 in the presence of Hb C or Hb E by reverse phase high performance liquid chromatography. Hemoglobin 10 (1986) 253-257
23. Orkin S.H., Kazazian Jr. H.H., Antonarakis S.E., Ostrer H., Goff S.C., and Sexton J.P. Abnormal RNA processing due to the exon mutation of beta E-globin gene. Nature 300 (1982) 768-769
24. Bunn H.F., and McDonald M.J. Electrostatic interactions in the assembly of haemoglobin. Nature 306 (1983) 498-500