A proteomic study of myosin II motor proteins during tumor cell migration

Journal of Molecular Biology

Volumn 407, Issue 5, 2011, Pages 673-686

  Betapudi, Venkaiah ^a,b   Gokulrangan, Giridharan ^b   Chance, Mark R ^b   Egelhoff, Thomas T ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cell migration; cytoskeleton; myosin II; phosphorylation

Indexed keywords

CASEIN KINASE II; FIBRONECTIN; INTEGRIN; MYOSIN HEAVY CHAIN; MYOSIN II; PROTEIN KINASE C; RNA;

ARTICLE; BREAST CANCER; CANCER CELL; CELL MIGRATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMELLAR BODY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEOMICS; RECEPTOR UPREGULATION; STAINING;

EID: 79952739523     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.02.010     Document Type: Article

References (30)

1. Conti, M. A. & Adelstein, R. S. (2008). Nonmuscle myosin II moves in new directions. J. Cell Sci. 121, 11-18.
2. Ridley, A. J., Schwartz, M. A., Burridge, K., Firtel, R. A., Ginsberg, M. H., Borisy, G. et al. (2003). Cell migration: integrating signals from front to back. Science, 302, 1704-1709. (Pubitemid 37505725)
3. Yilmaz, M. & Christofori, G. (2010). Mechanisms of motility in metastasizing cells. Mol. Cancer Res. 8, 629-642.
4. Lammermann, T., Bader, B. L., Monkley, S. J., Worbs, T., Wedlich-Soldner, R., Hirsch, K. et al. (2008). Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature, 453, 51-55. (Pubitemid 351630331)
5. Vicente-Manzanares, M., Ma, X., Adelstein, R. S. & Horwitz, A. R. (2009). Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat. Rev. Mol. Cell Biol. 10, 778-790.
6. Even-Faitelson, L. & Ravid, S. (2006). PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assembly. Mol. Biol. Cell, 17, 2869-2881.
7. Ludowyke, R. I., Peleg, I., Beaven, M. A. & Adelstein, R. S. (1989). Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells. J. Biol. Chem. 264, 12492-12501.
8. Dulyaninova, N. G., House, R. P., Betapudi, V. & Bresnick, A. R. (2007). Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol. Biol. Cell, 18, 3144-3155.
9. Dulyaninova, N. G., Malashkevich, V. N., Almo, S. C. & Bresnick, A. R. (2005). Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry, 44, 6867-6876. (Pubitemid 40632405)
10. Breckenridge, M. T., Dulyaninova, N. G. & Egelhoff, T. T. (2009). Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. Mol. Biol. Cell, 20, 338-347.
11. Kelley, C. A. & Adelstein, R. S. (1990). The 204-kDa smooth muscle myosin heavy chain is phosphorylated in intact cells by casein kinase II on a serine near the carboxyl terminus. J. Biol. Chem. 265, 17876-17882.
12. Murakami, N., Chauhan, V. P. & Elzinga, M. (1998). Two nonmuscle myosin II heavy chain isoforms expressed in rabbit brains: filament forming properties, the effects of phosphorylation by protein kinase C and casein kinase II, and location of the phosphorylation sites. Biochemistry, 37, 1989-2003. (Pubitemid 28099823)
13. Murakami, N., Healy-Louie, G. & Elzinga, M. (1990). Amino acid sequence around the serine phosphorylated by casein kinase II in brain myosin heavy chain. J. Biol. Chem. 265, 1041-1047.
14. Betapudi, V., Licate, L. S. & Egelhoff, T. T. (2006). Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. Cancer Res. 66, 4725-4733.
15. Betapudi, V. (2010). Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. PLoS ONE, 5, e8560.
16. Cai, Y., Biais, N., Giannone, G., Tanase, M., Jiang, G., Hofman, J. M. et al. (2006). Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow. Biophys. J. 91, 3907-3920. (Pubitemid 44788333)
17. Even-Ram, S., Doyle, A. D., Conti, M. A., Matsumoto, K., Adelstein, R. S. & Yamada, K.M. (2007). Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat. Cell Biol. 9, 299-309.
18. Matsumura, F., Ono, S., Yamakita, Y., Totsukawa, G. & Yamashiro, S. (1998). Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J. Cell Biol. 140, 119-129. (Pubitemid 28070900)
19. Steimle, P. A., Naismith, T., Licate, L. & Egelhoff, T. T. (2001). WD repeat domains target Dictyostelium myosin heavy chain kinases by binding directly to myosin filaments. J. Biol. Chem. 276, 6853-6860.
20. Moussavi, R. S., Kelley, C. A. & Adelstein, R. S. (1993). Phosphorylation of vertebrate nonmuscle and smooth muscle myosin heavy chains and light chains. Mol. Cell Biochem. 127-128, 219-227.
21. Niefind, K., Raaf, J. & Issinger, O. G. (2009). Protein kinase CK2 in health and disease: protein kinase CK2: from structures to insights. Cell Mol. Life Sci. 66, 1800-1816.
22. Llorens, F., Miro, F. A., Casanas, A., Roher, N., Garcia, L., Plana, M. et al. (2004). Unbalanced activation of ERK1/2 and MEK1/2 in apigenin-induced HeLa cell death. Exp. Cell Res. 299, 15-26.
23. de la Roche, M. A., Smith, J. L., Betapudi, V., Egelhoff, T. T. & Côté, G. P. (2002). Signaling pathways regulating Dictyostelium myosin II. J. Muscle Res. Cell Motil. 23, 703-718.
24. Ludowyke, R. I., Elgundi, Z., Kranenburg, T., Stehn, J. R., Schmitz-Peiffer, C., Hughes, W. E. & Biden, T. J. (2006). Phosphorylation of nonmuscle myosin heavy chain IIA on Ser1917 is mediated by protein kinase C beta II and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells. J. Immunol. 177, 1492-1499. (Pubitemid 44092482)
25. Webb, D. J., Donais, K., Whitmore, L.A., Thomas, S.M., Turner, C. E., Parsons, J. T. & Horwitz, A. F. (2004). FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat. Cell Biol. 6, 154-161.
26. Adelstein, R. S. & Pollard, T. D. (1978). Platelet contractile proteins. Prog. Hemostasis Thromb. 4, 37-58.
27. Trembley, J. H., Wang, G., Unger, G., Slaton, J. & Ahmed, K. (2009). Protein kinase CK2 in health and disease: CK2: a key player in cancer biology. Cell Mol. Life Sci. 66, 1858-1867.
28. Murakami, N., Kotula, L. & Hwang, Y. W. (2000). Two distinct mechanisms for regulation of nonmuscle myosin assembly via the heavy chain: phosphorylation for MIIB and mts 1 binding for MIIA. Biochemistry, 39, 11441-11451.
29. Breckenridge, M. T., Egelhoff, T. T. & Baskaran, H. (2010). A microfluidic imaging chamber for the direct observation of chemotactic transmigration. Biomed. Microdevices, 12, 543-553.
30. Betapudi, V., Mason, C., Licate, L. & Egelhoff, T. T. (2005). Identification and characterization of a novel α-kinase with a von Willebrand factor α-like motif localized to the contractile vacuole and Golgi complex in Dictyostelium discoideum. Mol. Biol. Cell, 16, 2248-2262.