Pharmacological mechanism responsible for the Atractylodes japonica-induced distal colonic contraction in rats

Phytomedicine

Volumn 18, Issue 5, 2011, Pages 408-413

  Choi, Keun Han ^a   Jeong, Seung Il ^b   Lee, Jun Ho ^a   Hwang, Byung Soon ^b   Kim, Sang Jun ^b   Lee, Seoul ^a   Choi, Bong Kyu ^a   Jung, Kyu Yong ^a  

^a Wonkwang University School of Medicine   (South Korea)

^b Jeonju Bio Materials Institute   (South Korea)

Author keywords

Atractylodes japonica; Choline acetyltransferase; Contractility; Distal colon longitudinal muscle; EtOAc extract; Muscarinic receptor

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ACETIC ACID ETHYL ESTER; ACETYLCHOLINE; ATRACTYLODES JAPONICA EXTRACT; BUTANOL; CHLOROFORM; FENCLONINE; GASTROINTESTINAL AGENT; HEXANE; METHANOL; METHOCTRAMINE; METHYSERGIDE; ONDANSETRON; PLANT EXTRACT; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATRACTYLODES; ATRACTYLODES JAPONICA; CONTROLLED STUDY; DESCENDING COLON; DRUG MECHANISM; DRUG SCREENING; MALE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; STOMACH MUSCLE;

ANIMALS; ATRACTYLODES; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL MOTILITY; INTESTINAL MUCOSA; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLINERGIC;

ASTERACEAE; ATRACTYLODES JAPONICA; RATTUS;

EID: 79952736221     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.08.010     Document Type: Article

References (22)

1. Barocelli, E., Ballabeni, V., Chiavarini, M., Caretta, A., Molina, E., Impicciatore, M., 1995. Regional differences in motor responsiveness to antimuscarinic drugs in rabbit isolated small and large intestine. Pharmacol. Res. 31, 43-48.
2. 3 receptors in the rat and mouse intestinal tracts: a comparative study. Br. J. Pharmacol. 148, 1012-1021.
3. Choi, E.M., Kim, G.H., Lee, Y.S., 2009. Atractylodes japonica root extract protects osteoblastic MC3T3-E1 cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation. Phytother. Res. 23, 1537-1542.
4. 3 muscarinic receptors in gastrointestinal, airway and urinary bladder smooth muscle. Life Sci. 74, 355-366.
5. Heldman, E., Barg, J., Fisher, A., Levy, R., Pittel, Z., Zimlichman, R., Kushnir, M., Vogel, Z., 1996. Pharmacological basis for functional selectivity of partial muscarinic receptor antagonists. Eur. J. Pharmacol. 297, 283-291.
6. Hikino, H., Hikino, Y., Yosioka, I., 1964. Studies on the constituents of Atractylodes. IX. Structure and autoxidation of atractylon. Chem. Pharm. Bull. 12, 755-760.
7. 3 receptors. J. Pharmacol. Exp. Ther. 288, 93-97.
8. Jeong, S.I., Kim, Y.S., Lee, M.Y., Kang, J.K., Lee, S., Choi, B.K., Jung, K.Y., 2009. Regulation of contractile activity by magnolol in the rat isolated gastrointestinal tracts. Pharmacol. Res. 59, 183-188.
9. Jang, M.H., Shin, M.C., Kim, Y.J., Kim, C.J., Kim, Y.H., Kim, E.H., 2004. Atractylodes japonica suppresses lipopolysaccharide-stimulated expression of inducible nitric oxide synthase and cyclooxygenase-2 in RAW 264.7 macrophages. Biol. Pharm. Bull. 27, 324-327.
10. Kim, D.Y., Camilleri, M., 2000. Serotonin: a mediator of the brain-gut connection. Am. J. Gastroenterol. 95, 2698-2709.
11. Kitajima, J.K., Kamoshita, A., Ishikawa, T., Takano, A., Fukuda, T., Isoda, S., Ida, Y., 2003. Glycosides of Atractylodes japonica. Chem. Pharm. Bull. 51, 152-157.
12. Kim, J.H., Lee, G.S., Choi, G., Hwang, S.Y., Kim, H.J., Jeong, S.I., Ju, Y.S., 2009. A study on external internal morphology and pattern analysis of Atractylodes rhizomes. Korean J. Herbol. 24, 77-85.
13. Kim, C.M., Shin, M.K., Ahn, D.G., Lee, K.S., 1997. Chungyak Daesajun. Jungdam Publisher, Seoul.
14. Li, C.Q., He, L.C., Jin, J.Q., 2007. Atractylenolide I and atractylenolide III inhibit lipopolysaccharide-induced TNF-α and NO production in macrophages. Phytother. Res. 21, 347-353.
15. Lee, S.O., Seo, J.H., Lee, J.W., Yoo, M.Y., Kwon, J.W., Choi, S.U., Kang, J.S., Kwon, D.Y., Kim, Y.K., Kim, Y.S., Ryu, S.Y., 2005. Inhibitory effects of the rhizome extract of Atractylodes japonica on the proliferation of human tumor cell lines. Korean J. Pharmacogn. 36, 201-204.
16. Majcen, Z., Brzin, M., 1979. Cholinesterase and choline acetyltransferase in the longitudinal muscle of the guinea pig ileum. Histochemistry 63, 295-302. (Pubitemid 10204821)
17. Sallanon, M., Buda, C., Janin, M., Jouvet, M., 1982. 5-HT antagonists suppress sleep and delay its restoration after 5-HTP in p-cholophenyalanine- pretreated cats. Eur. J. Pharmacol. 82, 29-35.
18. 2 state. Biochem. Pharmacol. 51, 339-343.
19. Sakurai, T., Sugawara, H., Saito, K., Kano, Y., 1994. Effects of the acetylene compound from Atractylodes rhizome on experimental gastric ulcers induced by active oxygen species. Biol. Pharm. Bull. 17, 1364-1368.
20. Talley, N.J., 2001. Serotoninergic neuroenteric modulators. Lancet 358, 2061-2068. (Pubitemid 34084835)
21. Taniyama, K., Makimoto, N., Furuichi, A., Sakurai-Yamashita, Y., Nagase, Y., Kaibara, M., Kanematsu, T., 2000. Function of peripheral 5-hydroxytryptamine receptors, especially 5-hydroxytryptamine4 receptor, in gastrointestinal motility. J. Gastroenterol. 35, 575-582. (Pubitemid 30649493)
22. Yu, P.L., Fujimura, M., Okumiya, K., Kinoshita, M., Hasegawa, H., Fujimiya, M., 1999. Immunohistochemical localization of tryptophan hydroxylase in the human and rat gastrointestinal tracts. J. Comp. Neurol. 411, 654-665.