Specific inhibition of Na+,K+-ATPase activity by Atractylon, a major component of Byaku-jutsu, by interaction with enzyme in the E2 state

Biochemical Pharmacology

Volumn 51, Issue 3, 1996, Pages 339-343

  Satoh, Kanako ^a   Nagai, Fumiko ^a   Ushiyama, Keiko ^a   Kano, Itsu ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Atractylon; Byaku jutsu; K+ pNPPase; Na+,K+ ATPase; Rhizomes of Atractylodes japonica

Indexed keywords

4 NITROPHENYLPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ATRACTYLON; POTASSIUM CHLORIDE; SESQUITERPENE; SODIUM CHLORIDE; ACID PHOSPHATASE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM); ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; ATRACTYLODES EXTRACT; ATRACTYLODES JAPONICA EXTRACT; BYAKU JUTSU; CHINESE DRUG; PLANT EXTRACT; POTASSIUM ION; PROTON PUMP; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CHINESE MEDICINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HORSE; ISOLATION AND PURIFICATION; KIDNEY; MEDICINAL PLANT; PHOSPHORYLATION; RAT; STOMACH MUCOSA; ANIMAL TISSUE; BRAIN MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPHOSPHORYLATION; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; TRADITIONAL MEDICINE;

4-NITROPHENYLPHOSPHATASE; ANIMALS; GASTRIC MUCOSA; HORSES; KIDNEY; MEDICINE, CHINESE TRADITIONAL; NA(+)-K(+)-EXCHANGING ATPASE; PHOSPHORYLATION; PLANTS, MEDICINAL; POTASSIUM CHLORIDE; RATS; SESQUITERPENES; SODIUM CHLORIDE;

EID: 0029664669     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02188-4     Document Type: Article

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