A factorial randomized controlled trial to evaluate the effect of micronutrients supplementation and regular aerobic exercise on maternal endothelium-dependent vasodilatation and oxidative stress of the newborn

Trials

Volumn 12, Issue , 2011, Pages

  Ramírez Vélez, Robinson ^a   Romero, Miryam ^a   Echeverri, Isabella ^a   Ortega, José G ^a   Mosquera, Mildrey ^a   Salazar, Blanca ^a   Girón, Sandra L ^a,b   Saldarriaga, Wilmar ^a   Aguilar de Plata, Ana C ^a   Mateus, Julio C ^a,b  

^a UNIVERSIDAD DEL VALLE   (Colombia)

^b Fundacion FES Social   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; MALTODEXTRIN; NICOTINIC ACID; RETINOL; SELENIUM; ZINC; BIOLOGICAL MARKER; ISOPROSTANE DERIVATIVE; TRACE ELEMENT;

ADULT; AEROBIC EXERCISE; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY COMPOSITION; BODY HEIGHT; BODY MASS; BODY WEIGHT; BRACHIAL ARTERY; DIET SUPPLEMENTATION; DRUG EFFICACY; EXERCISE TOLERANCE; FACTORIAL DESIGN; FEMALE; FUNCTIONAL STATUS; HUMAN; MAJOR CLINICAL STUDY; MATERNAL CARE; MATERNAL WELFARE; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; OXIDATIVE STRESS; PHYSICAL ACTIVITY; PREGNANCY OUTCOME; PREGNANT WOMAN; PRENATAL CARE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; STRETCHING EXERCISE; TREATMENT RESPONSE; VASODILATATION; WALKING; BLOOD; CLINICAL TRIAL; COLOMBIA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COMBINATION; ECHOGRAPHY; EXERCISE; FETUS BLOOD; HYPEREMIA; METABOLISM; METHODOLOGY; NEWBORN; PATHOPHYSIOLOGY; PREGNANCY; TIME; VASCULAR ENDOTHELIUM;

BIOLOGICAL MARKERS; BRACHIAL ARTERY; COLOMBIA; DIETARY SUPPLEMENTS; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; EXERCISE; F2-ISOPROSTANES; FEMALE; FETAL BLOOD; HUMANS; HYPEREMIA; INFANT, NEWBORN; MATERNAL WELFARE; MICRONUTRIENTS; OXIDATIVE STRESS; PREGNANCY; PRENATAL CARE; RESEARCH DESIGN; SINGLE-BLIND METHOD; TIME FACTORS; VASODILATION;

EID: 79952707483     PISSN: 17456215     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-12-60     Document Type: Article

References (40)

1. Sharkey D, Gardner DS, Symonds ME, Budge H. Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring. Am J Physiol Renal Physiol 2009, 297:F1199-207. 10.1152/ajprenal.00303.2009, 2781328, 19759269.
2. Mensah GA, Catravas JD, Engelgau MM, Hooper WC, Madeddu P, Ryan US, She JX, Reed E, Vinicor F, Yacoub MH. Vascular endothelium summary statement VI: Research directions for the 21st century. Vascul Pharmacol 2007, 46:330-332. 10.1016/j.vph.2006.10.016, 17222586.
3. Mensah G. Healthy endothelium: The scientific basis for cardiovascular health promotion and chronic disease prevention. Vascul Pharmacol 2006, 46:310-314. 10.1016/j.vph.2006.10.013, 17229594.
4. Hooper WC, Catravas JD, Heistad DD, Sessa WC, Mensah GA. Vascular endothelium summary statement I: Health promotion and chronic disease prevention. Vascul Pharmacol 2007, 46:315-317. 10.1016/j.vph.2006.10.014, 17197248.
5. Verhaar M, Rabelink T. The endothelium: a gynecological and obstetric point of view. Eur J Obstet Gynecol Reprod Biol 2001, 94:180-185. 10.1016/S0301-2115(00)00334-1, 11165722.
6. Lopez-Garcia E, Schulze MB, Fung TT, Meigs JB, Rifai N, Manson JE, Hu FB. Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr 2004, 80:1029-1035.
7. Horton ES. Effects of Lifestyle Changes to Reduce Risks of Diabetes and Associated Cardiovascular Risks: Results from Large Scale Efficacy Trials. Obesity (Silver Spring) 2009, 17(n3s):S43-S48. 10.1038/oby.2009.388, 19927146.
8. Teixeira V, Valente H, Casal S, Marques F, Moreira P. Antioxidant status, oxidative stress, and damage in elite trained kayakers and canoeists and sedentary controls. Int J Sport Nutr Exerc Metab 2009, 5:443-456.
9. Di F, Sciartilli A, Di Valerio V, Di Baldassarre A, Gallina S. The effect of physical exercise on endothelial function. Sports Med 2009, 39:797-812. 10.2165/11317750-000000000-00000, 19757859.
10. Song Y, Li TY, van Dam RM, Manson JE, Hu FB. Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in women. Am J Clin Nutr 2007, 85:1068-1074.
11. Yeo S. A randomized comparative trial of the efficacy and safety of exercise during pregnancy: Design and methods. Contemp Clin Trials 2006, 27:531-540. 10.1016/j.cct.2006.06.005, 16861054.
12. Mostyn A, Symonds ME. Early programming of adipose tissue function: a large-animal perspective. Proc Nutr Soc 2009, 68:393-400. 10.1017/S002966510999022X, 19719893.
13. Alderman BW, Zhao H, Holt VL, Watts DH, Beresford SA. Maternal Physical Activity in Pregnancy and Infant Size for Gestational Age. Ann Epidemiol 1998, 8:513-519. 10.1016/S1047-2797(98)00020-9, 9802596.
14. Joseph K, Kramer M. Should we intervene to improve fetal and infant growth?. A life Course Approach to Chronic Disease Epidemiology 2004, New York: Oxford University Press, Kuh D, Ben-Shlomo Y, Second.
15. Hegaard HK, Pedersen BK, Nielsen BB, Damm P. Leisure time physical activity during pregnancy and impact on gestational diabetes mellitus, pre-eclampsia, preterm delivery and birth weight: a review. Acta Obstet Gynecol Scand 2007, 86:1290-1296. 10.1080/00016340701647341, 17851805.
16. Gavard JA, Artal R. Effect of exercise on pregnancy outcome. Clin Obstet Gynecol 2008, 51:467-480. 10.1097/GRF.0b013e31816feb1d, 18463475.
17. Herrera JA, Arevalo-Herrera M, Herrera S. Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. Obstet Gynecol 1998, 91:585-590. 10.1016/S0029-7844(97)00711-4, 9540946.
18. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 267, January 2002 Exercise during pregnancy and the postpartum period. Obstet Gynecol 2002, 99:171-173. 10.1016/S0029-7844(01)01749-5, 11777528, ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 267, January 2002.
19. ACSM's Guidelines for Exercise Testing and Prescription. 2000, Philadelphia, PA: Lippincott Williams & Wilkins, 6, ACSM's.
20. Wittes J. Sample Size Calculations for Randomized Controlled Trials. Epidemiol Rev 2002, 24:39-53. 10.1093/epirev/24.1.39, 12119854.
21. Heymans MW, van Buuren S, Knol DL, van Mechelen W, de Vet HC. Variable selection under multiple imputation using the bootstrap in a prognostic study. BMC Med Res Methodol 2007, 13(7):33.
22. Graham JW. Missing Data Analysis: Making it Work in the Real World. Annu Rev Psychol 2009, 60:549-76. 10.1146/annurev.psych.58.110405.085530, 18652544.
23. Wood AM, White IR. Thompson SG. Are Missing Outcome Data Adequatelt Handled? A Review of Published Randomized Controlled Trials in Major Medical Journals. Clin Trials 2004, 1:368-76. 10.1191/1740774504cn032oa, 16279275.
24. Armitage P, Berry G, . Further Experimental Designs Statistical Methods in Medical Research. 1994, 237-82. London: Blackwell Scientific Publications, Armitage P, Berry G, Third, Further Experimental Designs.
25. Sheskin D, . Test 22. The Kruskall-Wallis One-Way Analysis of Variance by Ranks Handbook of Parametric and Nonparametric Statistical Procedures. 2000, 595-609. Boca Raton: CHAPMAN & HALL/CRC, Sheskin D, Second, Test 22. The Kruskall-Wallis One-Way Analysis of Variance by Ranks.
26. Kleinbaum DG, Kupper LL, Muller KE, Nizam A. Applied Regression Analysis and Other Multivariable Methods. 1998, Dubury Press: Pacific Grove.
27. Standarizaton of anthropometric measurements. The Airle (VA) consensus Conference. Champaign, 11: Human Kinetics 1988, 39-80. Lohman T, Roche A, Martorel R.
28. Pickering TG. Recommendations for the use of home (self) and ambulatory blood pressure monitoring. American Society of Hypertension Ad Hoc Panel. Am J Hypertens 1996, 9:1-11. 10.1016/0895-7061(95)00341-X, 8834700.
29. Kyle UG, Schutz Y, Dupertuis YM, Pichard C. Body composition interpretation. Contributions of the fat-free mass index and the body fat mass index. Nutrition 2003, 19:597-604. 10.1016/S0899-9007(03)00061-3, 12831945.
30. Silva SY, Villamizar C, Villamizar N, Silva F, Luengas C, Casas JP, Villa-Roel C, López-Jaramillo P. Colombian study to assess the use of noninvasive determination of Endothelium-mediated vasodilation (CANDEV). II. Does location of the occlusion device affects Diagnostic accuracy?. Endothelium 2005, 12:107-111. 10.1080/10623320500189798, 16291513.
31. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, Herrington D, Vallance P, Vita J, Vogel R, . International Brachial Artery Reactivity Task Force International brachial artery reactivity task force. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the international brachial artery reactivity task force. J Am Coll Cardiol 2002, 39:257-265. 10.1016/S0735-1097(01)01746-6, 11788217, International Brachial Artery Reactivity Task Force.
32. Sorensen KE, Celermajer DS, Spiegelhalter DJ, Georgakopoulos D, Robinson J, Thomas O, Deanfield JE. Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility. Br Heart J 1995, 74:247-253. 10.1136/hrt.74.3.247, 484014, 7547018.
33. Milne GL, Yin H, Brooks JD, Sanchez S, Jackson Roberts L, Morrow JD. Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. Methods Enzymol 2007, 433:113-126. full_text, 17954231.
34. Liu W, Morrow JD, Yin H. Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method. Free Radic Biol Med 2009, 47:1101-1107. 10.1016/j.freeradbiomed.2009.07.028, 2749920, 19647073.
35. Chasan-Taber L, Schmidt MD, Roberts DE, Hosmer D, Markenson G, Freedson PS. Development and validation of a Pregnancy Physical Activity Questionnaire. Med Sci Sports Exerc 2004, 36:1750-1760. 10.1249/01.MSS.0000142303.49306.0D, 15595297.
36. Vilagut G, Valderas JM, Ferrer M, Garin O, Lopez-Garcia E, Alonso J. Interpretation of SF-36 and SF-12 questionnaires in Spain: physical and mental components. Med Clin 2008, 130:726-735.
37. Barakat R, Stirling JR, Lucia A. Does exercise training during pregnancy affect gestational age? A randomised controlled trial. Br J Sports Med 2008, 42:674-648. 10.1136/bjsm.2008.047837, 18552370.
38. Boutron I, Moher D, Altman DG, Schulz K, Ravaud P, . for the CONSORT group Extending the CONSORT Statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med 2008, 148:295-309. for the CONSORT group.
39. Ramírez-Vélez R, Aguilar AC, Mosquera M, García RG, Reyes LM, López-Jaramillo P. Clinical trial to assess the effect of physical exercise on endothelial function and insulin resistance in pregnant women. Trials 2009, 10:104. 2784447, 19919718.
40. Echeverry I, Ramírez-Vélez R, Mosquera M, Mateus JC, Aguilar AC. Potencial efecto del ejercicio físico y del consumo de micronutrientes durante la gestación en factores maternos y placentarios asociados a Enfermedades Crónicas No transmisibles (ECNT) del adulto. Colomb Med 2009, 40:435-446.