An attenuated Salmonella enterica serovar Typhimurium strain lacking the ZnuABC transporter induces protection in a mouse intestinal model of Salmonella infection

Vaccine

Volumn 29, Issue 9, 2011, Pages 1783-1790

  Pesciaroli, M ^a   Aloisio, F ^b   Ammendola, S ^c   Pistoia, C ^a   Petrucci, P ^a   Tarantino, M ^a   Francia, M ^a   Battistoni, A ^c   Pasquali, P ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Enteric salmonellosis; Immune response; Mouse; Salmonella; Vaccine

Indexed keywords

ABC TRANSPORTER; SALMONELLOSIS VACCINE; STREPTOMYCIN; ZINC TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; COLITIS; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; INFECTION PREVENTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; TYPHLITIS;

EID: 79952707076     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.12.111     Document Type: Article

References (32)

1. Mastroeni P, Chabalgoity JA, Dunstan SJ, Maskell DJ, Dougan G. Salmonella: immune responses and vaccines. Vet J 2001;161:132-64.
2. Galan JE. Salmonella interactions with host cells: type III secretion at work. Annu Rev Cell Dev Biol 2001;17:53-86.
3. Barthel M, Hapfelmeier S, Quintanilla-Martínez L, Kremer M, Rohde M, Hogardt M, et al. Pretreatment of mice with streptomycin provides a Salmonella enterica Serovar Typhimurium Colitis model that allows analysis of both pathogen and host. Infect Immun 2003;71:2839-58.
4. Galyov EE, Wood MW, Rosqvist R, Mullan PB, Watson PR, Hedges S, et al. A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa. Mol Microbiol 1997;25:903-12.
5. Stecher B, Hardt WD. The role of microbiotain infectious disease. Trends Microbiol 2008;16:107-14.
6. Stecher B, Robbiani R, Walker AW, Westendorf AM, Barthel M, Kremer M, et al. Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol 2007;5:2177-89.
7. Stecher B, Paesold G, Barthel M, Kremer M, Jantsch J, Stallmach T, et al. Chronic Salmonella enterica serovar Typhimurium-induced colitis and cholangitis in streptomycin-pretreated Nramp1+/+ mice. Infect Immun 2006;74:5047-57.
8. EFSA. The Community Summary Report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in the European Union in 2008, http://www.efsa.europa.eu/en/scdocs/scdoc/1496.htm; 2009.
9. Barrow PA, Page K, Lovell MA. The virulence for genotobiotic pigs of live attenuated vaccine strains of Salmonella enterica serovars typhimurium and enteritidis. Vaccine 2001;19:3432-6.
10. Denagamage TN, O'Connor AM, Sargeant JM, Rajić A, McKean JD. Efficacy of vaccination to reduce Salmonella prevalence in live and slaughtered swine: a systematic review of literature from 1979 to 2007. Foodborne Pathog Dis 2007;4:539-49.
11. Fosse J, Seegers H, Magras C. Prevalence and risk factors for bacterial food-borne zoonotic hazards in slaughter pigs: a review. Zoonoses Public Health 2009;56:429-54.
12. Boyen F, Haesebrouck F, Maes D, Van Immerseel F, Ducatelle R, Pasmans F. Non-typhoidal Salmonella infections in pigs: a closer look at epidemiology, pathogenesis and control. Vet Microbiol 2008;130:1-19.
13. Pasquali P, Ammendola S, Pistoia C, Petrucci P, Tarantino M, Valente C, et al. Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice. Vaccine 2008;26:3421-6.
14. 2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica. Infect Immun 2007;75:5867-76.
15. Wales A, Breslin M, Davies R. Assessment of cleaning and disinfection in Salmonella-contaminated poultry layer houses using qualitative and semi-quantitative culture techniques. Vet Microbiol 2006;116:283-93.
16. Stecher B, Macpherson AJ, Hapfelmeier S, Kremer M, Stallmach T, Hardt WD. Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infect Immun 2005;73:3228-41.
17. Hapfelmeier S,Stecher B,Barthel M, Kremer M, Müller AJ, Heikenwalder M, et al. The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. J Immunol 2005;174:1675-85.
18. Hapfelmeier S, Müller AJ, Stecher B, Kaiser P, Barthel M, Endt K, et al. Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. J Exp Med 2008;205:437-50.
19. Valdez Y, Grassl GA, Guttman JA, Coburn B, Gros P, Vallance BA, et al. Nramp1 drivesanaccelerated inflammatory response during Salmonella-induced colitis in mice. Cell Microbiol 2009;11:351-62.
20. Suar M, Jantsch J, Hapfelmeier S, Kremer M, Stallmach T, Barrow PA, et al. Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infect Immun 2006;74:632-44.
21. Hapfelmeier S, Hardt WD. A mouse model for S. typhimurium-induced entero-colitis. Trends Microbiol 2005;13:497-503.
22. Loynachan AT, Harris DL. Dose determination for acute Salmonella infection in pigs. Appl Environ Microbiol 2005;71:2753-5.
23. Mastroeni P, Villarreal-Ramos B, Hormaeche CE. Role of T cells, TNF alpha and IFN gammain recall of immunity to oral challenge with virulent salmonellae in mice vaccinated with live attenuated aro-Salmonella vaccines. Microb Pathog 1992;13:477-91.
24. Bao S, Beagley KW, France MP, Shen J, Husband AJ. Interferon-gamma plays a critical role in intestinal immunity against Salmonella typhimurium infection. Immunology 2000;99:464-72.
25. Seibert SA, Mex P, Köhler A, Kaufmann SH, Mittrücker HW. TLR2-, TLR4- and Myd88-independent acquired humoral and cellular immunity against Salmonella enterica serovar Typhimurium. Immunol Lett 2010;12:126-34.
26. Santos RL, Zhang S, Tsolis RM, Kingsley RA, Adams LG, Bäumler AJ. Animal models of Salmonella infections: enteritis versus typhoid fever. Microbes Infect 2001;31:335-44.
27. Splíchal I, Trebichavský I, Muneta Y, Mori Y. Early cytokine response of gnotobiotic piglets to Salmonella enterica serotype Typhimurium. Vet Res 2002;33:291-7.
28. Eckmann L. Animal models of inflammatory bowel disease: lessons from enteric infections. Ann N Y Acad Sci 2006;1072:28-38.
29. Trebichavsky I, Splichalova A, Rychlik I, Hojna H, Muneta Y, Mori Y, et al. Attenuated aroA Salmonella enterica serovar Typhimurium does not induce inflammatory response and early protection of gnotobiotic pigs against parental virulent LT2 strain. Vaccine 2006;24:4285-9.
30. Splíchal I, Trebichavský I, Splíchalová A, Barrow PA. Protection of gnotobiotic pigs against Salmonella enterica serotype Typhimurium by rough mutant of the same serotype is accompanied by the change of local and systemic cytokine response. Vet Immunol Immunopathol 2005;103:155-61.
31. Carnell SC, Bowen A, Morgan E, Maskell DJ, Wallis TS, Stevens MP. Role in virulence and protective efficacy in pigs of Salmonella enterica serovar Typhimurium secreted components identified by signature-tagged mutagenesis. Microbiology 2007;153:1940-52.
32. Boyen F, Pasmans F, Van Immerseel F, Donne' E, Morgan E, Ducatelle E, et al. Porcine in vitro and in vivo models toassess the virulenceof Salmonella enterica serovar Typhimurium for pigs. Lab Animals 2009;43:46-52.