Glucose transporter-1 (GLUT-1) immunoreactivity in benign, premalignant and malignant lesions of the gallbladder

Pathology and Oncology Research

Volumn 17, Issue 1, 2011, Pages 61-66

  Legan, Mateja ^a   Tevžič, Špela ^a   Tolar, Ana ^a   Luzar, Boštjan ^a   Marolt, Vera Ferlan ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Diagnosis; Gallbladder adenocarcinoma; GLUT 1; Immunohistochemistry; Prognosis

Indexed keywords

GLUCOSE TRANSPORTER 1;

ADULT; AGED; ARTICLE; BENIGN TUMOR; CANCER GRADING; CHOLECYSTECTOMY; CONTROLLED STUDY; DYSPLASIA; FEMALE; GALLBLADDER CARCINOMA; GALLBLADDER TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; PRECANCER; PROTEIN EXPRESSION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; EXCITATORY AMINO ACID TRANSPORTER 2; FEMALE; GALLBLADDER NEOPLASMS; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PRECANCEROUS CONDITIONS; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 79952706237     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-010-9281-7     Document Type: Article

References (27)

1. Dills WL (1993) Nutritional and physiological consequences of tumor glycolysis. Parasitology 107:S177-S186
2. Pessin JE, Bell GI (1992) Mammalian facilitative glucose transporter family: structure and molecular regulation. Ann Rev Physiol 54:911-930
3. Ebert BL, Firth JD, Ratcliffe PJ (1995) Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct cis-acting sequences. J Biol Chem 270:29083-29089
4. Pardridge WM, Boado RJ, Farrell CR (1990) Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. J Biol Chem 265:18035-18040
5. Gould GW, Holman GD (1993) The glucose transporter family: structure, function and tissue-specific expression. Biochem J 53:4204-4211
6. Froehner SC, Davies A, Baldwin SA, Lienhard GE (1998) The blood-nerve barrier is rich in glucose transporter. J Neurocytol 17:173-178
7. Younes M, Lechago LV, Somoano JR, Mosharaf M, Lechago J (1996) Wide expression of the human erythrocyte glucose transporter Glut-1 in human cancers. Cancer Res 56:1164-1167 (Pubitemid 26065417)
8. Noguchi Y, Marat D, Saito A et al (1999) Expression of facilitative glucose transporters in gastric tumors. Hepato Gastroenterol 46:2683-2689 (Pubitemid 29454167)
9. Reisser C, Eichhorn K, Herold-Mende C, Born AL, Bannasch P (1999) Expression of facilitative glucose transporter proteins during development of squamous cell carcinomas of the head and neck. Int J Cancer 80:194-198 (Pubitemid 29001721)
10. Haber RS, Rathan A, Weiser KR et al (1998) GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis. Cancer 83:34-40 (Pubitemid 28299626)
11. Kalir T, Wang B, Goldfischer M et al (2002) Immunohistochemical staining of GLUT1 in benign, borderline, and malignant ovarian epithelia. Cancer 94:1078-1082 (Pubitemid 34150863)
12. Ashton-Sager A, Paulino AFG, Afify AM (2006) GLUT-1 is preferentially expressed in atypical endometrial hyperplasia and endometrial adenocarcinoma. Appl Immunohistochem Mol Morphol 14:187-192 (Pubitemid 43941183)
13. Chandan VS, Faquin WC, Wilbur DC, Khurana KK (2006) The utility of GLUT-1 immunolocalization in cell blocks: An adjunct to the fine needle aspiration diagnosis of cystic squamous lesions of the head and neck. Cancer 108:124-128
14. Ito H, Duxbury M, Zinner MJ, Ashley SW, Whang EE (2004) Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity. Surgery 136:548-556 (Pubitemid 39186566)
15. Grover-McKay M, Walsh SA, Seftor EA, Thomas PA, Hendrix MJC (1998) Role for glucose transporter 1 protein in human breast cancer. Pathol Oncol Res 4:115-120 (Pubitemid 28394627)
16. Chandan VS, Faquin WC, Wilbur DC, Khurana KK (2006) The role of immunolocalization of CD57 and GLUT-1 in cell blocks in fine-needle aspiration diagnosis of papillary thyroid carcinoma. Cancer 108:331-336 (Pubitemid 44583713)
17. Kim YW, Park YK, Yoon T, Lee SM (2002) Expression of GLUT-1 glucose transporter in gallbladder carcinomas. Hepatogastroenterol 49:907-911
18. Evans A, Bates V, Troy H et al (2008) GLUT-1 as a therapeutic target: increased chemoresistance and HIF-1 independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies. Cancer Chemother Pharmacol 61:377-393 (Pubitemid 350275973)
19. Legan M, Luzar B, Marolt VF (2009) Expression of cyclooxygenase-2, glucose transporter-1 and angiogenesis in gallbladder carcinomas and their impact on prognosis. Scand J Gastroenterol 44:1101-1108
20. Cooper R, Sarioglu S, Sökmen S et al (2003) Glucose transporter-1 (GLUT-1): a potential marker of prognosis in rectal carcinoma? Brit J Cancer 89:870-876
21. Kanoh K, Shimura T, Tsutsumi S et al (2001) Significance of contracted cholecystitis lesions as high risk for gallbladder carcinogenesis. Cancer Lett 169:7-14 (Pubitemid 32532090)
22. Tsuchida A, Itoi T, Aoki T, Koyanagi Y (2003) Carcinogenetic process in gallbladder mucosa with pancreaticobiliary maljunction. Oncol Rep 10:1693-1699
23. Roa I, Araya JC, Villaseca M et al (1996) Preneoplastic lesions and gallbladder cancer: an estimate of the period required for progression. Gastroenterol 111:232-236 (Pubitemid 26226904)
24. Cantuaria G, Fagotti A, Ferrandina G et al (2001) GLUT-1 expression in ovarian carcinoma: association with survival and response to chemotherapy. Cancer 92:1144-1150 (Pubitemid 32861663)
25. Griffiths EA, Pritchard SA, Welch IM et al (2005) Is the hypoxiainducible factor pathway important in gastric cancer? Eur J Cancer 41:2792-2805
26. Airley R, Loncaster J, Davidson S et al (2001) Glucose transporter Glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Clin Cancer Res 7:928-934 (Pubitemid 32708731)
27. Miller JH, Mullin JM, McAvoy E, Kleinzeller A (1992) Polarity of transport of 2-deoxy-D-glucose and D-glucose by cultured renal epithelia (LLC-PK1). Biochim Biophys Acta 1110:209-217