Clinical problems in the hospitalized Parkinson's disease patient: Systematic review

Movement Disorders

Volumn 26, Issue 2, 2011, Pages 197-208

  Gerlach, Oliver H H ^a   Winogrodzka, Ania ^a   Weber, Wim E J ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Emergency room; Hospitalization; Parkinson's disease; Perioperative

Indexed keywords

ASPIRATION PNEUMONIA; CONFUSION; DECUBITUS; DIARRHEA; DYSPHAGIA; FALLING; FRACTURE; HEAD INJURY; HEART ATRIUM FIBRILLATION; HIP FRACTURE; HORMONE SUBSTITUTION; HOSPITAL ADMISSION; HUMAN; HYPERTHERMIA; HYPOTENSION; INJURY; INTESTINE OBSTRUCTION; INTRAOPERATIVE PERIOD; LEG EDEMA; LOW BACK PAIN; MEDICAL ERROR; MEDLINE; NEUROLOGIC EXAMINATION; ORTHOSTATIC HYPOTENSION; PARKINSON DISEASE; PATIENT CARE; PATIENT COMPLIANCE; PATIENT SATISFACTION; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; SEPTICEMIA; SYSTEMATIC REVIEW; TRANSIENT ISCHEMIC ATTACK; URINARY TRACT INFECTION;

HOSPITALIZATION; HUMANS; PARKINSON DISEASE; PATIENT ADMISSION;

EID: 79952691812     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.23449     Document Type: Review

References (98)

1. Poos MJJC, Gijsen R. Ziekte van Parkinson. Omvang van het probleem. Achtergronden en details bij cijfers uit huisartsenregistraties. Nationaal Kompas Volksgezondheid, versie 319 2009. Accessed 1 November 2009. Available at: [].
2. Chapuis S, Ouchchane L, Metz O, Gerbaud L, Durif F. Impact of the motor complications of Parkinson's disease on the quality of life. Mov Disord 2005; 20: 224-230.
3. Rahman S, Griffin HJ, Quinn NP, Jahanshahi M. Quality of life in Parkinson's disease: the relative importance of the symptoms. Mov Disord 2008; 23: 1428-1434.
4. Martignoni E, Godi L, Citterio A, et al. Comorbid disorders and hospitalisation in Parkinson's disease: a prospective study. Neurol Sci 2004; 25: 66-71.
5. Antonini A, Miro L, Castiglioni C, Pezzoli G. The rationale for improved integration between home care and neurology hospital services in patients with advanced Parkinson's disease. Neurol Sci 2008; 29(Suppl 5): S392-S396.
6. Dorton DM. The care of patients with Parkinson's disease. J Post Anesth Nurs 1995; 10: 102-106.
7. Vergenz S. Caring for the Parkinson's patient: a nurse's perspective. Dis Mon 2007; 53: 243-251.
8. Stotz M, Thummler D, Schurch M, Renggli JC, Urwyler A, Pargger H. Fulminant neuroleptic malignant syndrome after perioperative withdrawal of antiParkinsonian medication. Br J Anaesth 2004; 93: 868-871.
9. Vargas AP, Carod-Artal FJ, Nunes SV, Melo M. Disability and use of healthcare resources in Brazilian patients with Parkinson's disease. Disabil Rehabil 2008;30: 1055-1062.
10. Cosentino M, Martignoni E, Michielotto D, et al. Medical healthcare use in Parkinson's disease: survey in a cohort of ambulatory patients in Italy. BMC Health Serv Res 2005; 5: 26.
11. Factor SA, Molho ES. Emergency department presentations of patients with Parkinson's disease. Am J Emerg Med 2000; 18: 209-215.
12. Huse DM, Schulman K, Orsini L, Castelli-Haley J, Kennedy S, Lenhart G. Burden of illness in Parkinson's disease. Mov Disord 2005; 20: 1449-1454.
13. Guneysel O, Onultan O, Onur O. Parkinson's disease and the frequent reasons for emergency admission. Neuropsychiatr Dis Treat 2008; 4: 711-714.
14. Parashos SA, Maraganore DM, O'Brien PC, Rocca WA. Medical services utilization and prognosis in Parkinson disease: a population-based study. Mayo Clin Proc 2002; 77: 918-925.
15. Vossius C, Nilsen OB, Larsen JP. Parkinson's disease and hospital admissions: frequencies, diagnoses and costs. Acta Neurol Scand 2010; 121: 38-43.
16. Klein C, Prokhorov T, Miniovitz A, Dobronevsky E, Rabey JM. Admission of Parkinsonian patients to a neurological ward in a community hospital. J Neural Transm 2009; 116: 1509-1512.
17. Louis ED, Henchcliffe C, Bateman BT, Schumacher C. Young-onset Parkinson's disease: hospital utilization and medical comorbidity in a nationwide survey. Neuroepidemiology 2007; 29: 39-43.
18. Temlett JA, Thompson PD. Reasons for admission to hospital for Parkinson's disease. Intern Med J 2006; 36: 524-526.
19. Woodford H, Walker R. Emergency hospital admissions in idiopathic Parkinson's disease. Mov Disord 2005; 20: 1104-1108.
20. Guttman M, Slaughter PM, Theriault ME, DeBoer DP, Naylor CD. Parkinsonism in Ontario: comorbidity associated with hospitalization in a large cohort. Mov Disord 2004; 19: 49-53.
21. Tan LC, Tan AK, Tjia HT. The profile of hospitalised patients with Parkinson's disease. Ann Acad Med Singapore 1998; 27: 808-812.
22. Kessler, II. Epidemiologic studies of Parkinson's disease. II. A hospital-based survey. Am J Epidemiol 1972; 95: 308-318.
23. Pressley JC, Louis ED, Tang MX, et al. The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism. Neurology 2003; 60: 87-93.
24. Guttman M, Slaughter PM, Theriault ME, DeBoer DP, Naylor CD. Burden of parkinsonism: a population-based study. Mov Disord 2003; 18: 313-319.
25. Pepper PV, Goldstein MK. Postoperative complications in Parkinson's disease. J Am Geriatr Soc 1999; 47: 967-972.
26. Idjadi JA, Aharonoff GB, Su H, et al. Hip fracture outcomes in patients with Parkinson's disease. Am J Orthop 2005; 34: 341-346.
27. Mueller MC, Juptner U, Wuellner U, et al. Parkinson's disease influences the perioperative risk profile in surgery. Langenbeck's archives of surgery/Deutsche Gesellschaft fur Chirurgie 2009; 394: 511-515.
28. Jonsson B, Sernbo I, Johnell O. Rehabilitation of hip fracture patients with Parkinson's disease. Scand J Rehabil Med 1995; 27: 227-230.
29. Mehta S, Vankleunen JP, Booth RE, Lotke PA, Lonner JH. Total knee arthroplasty in patients with Parkinson's disease: impact of early postoperative neurologic intervention. Am J Orthop 2008; 37: 513-516.
30. Londos E, Nilsson LT, Stromqvist B. Internal fixation of femoral neck fractures in Parkinson's disease. 32 patients followed for 2 years. Acta Orthop Scand 1989; 60: 682-685.
31. Magdalinou KN, Martin A, Kessel B. Prescribing medications in Parkinson's disease (PD) patients during acute admissions to a District General Hospital. Parkinsonism Relat Disord 2007; 13: 539-540.
32. Tanaka M, Suemaru K, Ikegawa Y, Tabuchi N, Araki H. Relationship between the risk of falling and drugs in an academic hospital. Yakugaku Zasshi 2008; 128: 1355-1361.
33. Golden WE, Lavender RC, Metzer WS. Acute postoperative confusion and hallucinations in Parkinson disease. Ann Intern Med 1989; 111: 218-222.
34. Severn AM. Parkinsonism and the anaesthetist. Br J Anaesth 1988; 61: 761-770.
35. Mason LJ, Cojocaru TT, Cole DJ. Surgical intervention and anesthetic management of the patient with Parkinson's disease. Int Anesthesiol Clin 1996; 34: 133-150.
36. Harada T, Mitsuoka K, Kumagai R, et al. Clinical features of malignant syndrome in Parkinson's disease and related neurological disorders. Parkinsonism Relat Disord 2003; 9(Suppl 1): S15-S23.
37. Kalenka A, Hinkelbein J. Anaesthesia in patients with Parkinson's disease. Der Anaesthesist 2005; 54: 401-409; quiz 410-401.
38. Goldberg LI. Anesthetic management of patients treated with antihypertensive agents or levodopa. Anesth Analg 1972; 51: 625-632.
39. Ong KC, Chew EL, Ong YY. Neuroleptic malignant syndrome without neuroleptics. Singapore Med J 2001; 42: 85-88.
40. Derry CP, Shah KJ, Caie L, Counsell CE. Medication management in people with Parkinson's disease during surgical admissions. Postgrad Med J 2010; 86: 334-337.
41. Barber M, Stewart D, Grosset D, MacPhee G. Patient and carer perception of the management of Parkinson's disease after surgery. Age Ageing 2001; 30: 171-172.
42. Simon D, Shapira OM, Mor E, Pfefferman R. Parkinson syndrome. A significant risk factor in the patient with acute surgical disorder. Int Surg 1992; 77: 313-316.
43. Duffy GP, Trousdale RT. Total knee arthroplasty in patients with parkinson's disease. J Arthroplasty 1996; 11: 899-904.
44. Eventov I, Moreno M, Geller E, Tardiman R, Salama R. Hip fractures in patients with Parkinson's syndrome. J Trauma 1983; 23: 98-101.
45. Staeheli JW, Frassica FJ, Sim FH. Prosthetic replacement of the femoral head for fracture of the femoral neck in patients who have Parkinson disease. J Bone Joint Surg Am 1988; 70: 565-568.
46. Vince KG, Insall JN, Bannerman CE. Total knee arthroplasty in the patient with Parkinson's disease. J Bone Joint Surg Br 1989; 71: 51-54.
47. Coughlin L, Templeton J. Hip fractures in patients with Parkinson's disease. Clin Orthop 1980;148: 192-195.
48. Weber M, Cabanela ME, Sim FH, Frassica FJ, Harmsen WS. Total hip replacement in patients with Parkinson's disease. Int Orthop 2002; 26: 66-68.
49. Rothermel JE, Garcia A. Treatment of hip fractures in patients with Parkinson's syndrome on levodopa therapy. J Bone Joint Surg Am 1972; 54: 1251-1254.
50. Turcotte R, Godin C, Duchesne R, Jodoin A. Hip fractures and Parkinson's disease. A clinical review of 94 fractures treated surgically. Clin Orthop 1990;256: 132-136.
51. Pritchett JW, Bortel DT. Parkinson's disease and femoral neck fractures treated by hemiarthroplasty. Clin Orthop 1992;279: 310-311.
52. Tabamo RE, Fernandez HH, Friedman JH, Lucas PR. Spinal surgery for severe scoliosis in Parkinson's disease. Med Health R I 2000; 83: 114-115.
53. Heckmann SM, Heckmann JG, Weber HP. Clinical outcomes of three Parkinson's disease patients treated with mandibular implant overdentures. Clin Oral Implants Res 2000; 11: 566-571.
54. Bryant C, Harley J. Re: Parkinson's disease patients who fracture their neck of femur: a review of outcome data. Injury 2007; 38: 1222.
55. Fast A, Mendelsohn E, Sosner J. Total knee arthroplasty in Parkinson's disease. Arch Phys Med Rehabil 1994; 75: 1269-1270.
56. Kryzak TJ, Sperling JW, Schleck CD, Cofield RH. Total shoulder arthroplasty in patients with Parkinson's disease. J Shoulder Elbow Surg 2009; 18: 96-99.
57. Babat LB, McLain RF, Bingaman W, Kalfas I, Young P, Rufo-Smith C. Spinal surgery in patients with Parkinson's disease: construct failure and progressive deformity. Spine (Phila Pa 1976) 2004; 29: 2006-2012.
58. Oni OO, Mackenney RP. Total knee replacement in patients with Parkinson's disease. J Bone Joint Surg Br 1985; 67: 424-425.
59. Clubb VJ, Clubb SE, Buckley S. Parkinson's disease patients who fracture their neck of femur: a review of outcome data. Injury 2006; 37: 929-934.
60. Koch LD, Cofield RH, Ahlskog JE. Total shoulder arthroplasty in patients with Parkinson's disease. J Shoulder Elbow Surg 1997; 6: 24-28.
61. Bohmdorfer W, Schwarzinger P, Binder S, Sporn P. Temporary suppression of tremor by remifentanil in a patient with Parkinson's disease during cataract extraction under local anesthesia. Anaesthesist 2003; 52: 795-797.
62. Clemente ML, Federici L, Brogi A, Civeli L, Giuntini L. Althesin - Fentanyl combination as anesthetic in patients with Parkinson's disease. Minerva Anestesiol 1980; 46: 675-680.
63. Stone DJ, DiFazio CA. Sedation for patients with Parkinson's disease undergoing ophthalmologic surgery. Anesthesiology 1988; 68: 821.
64. Sehgal A, Panchal ID. Postoperative bronchospasm in a patient with Parkinson's disease. Can J Anaesth 2001; 48: 214-215.
65. Backus WW, Ward RR, Vitkun SA, Fitzgerald D, Askanazi J. Postextubation laryngeal spasm in an unanesthetized patient with Parkinson's disease. J Clin Anesth 1991; 3: 314-316.
66. Oliveira E, Michel A, Smolley L. The pulmonary consultation in the perioperative management of patients with neurologic diseases. Neurol Clin 2004; 22: 277-291.
67. Burton DA, Nicholson G, Hall GM. Anaesthesia in elderly patients with neurodegenerative disorders: special considerations. Drugs Aging 2004; 21: 229-242.
68. Furuya R, Hirai A, Andoh T, Kudoh I, Okumura F. Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia. Anesthesiology 1998; 89: 261-263.
69. Broussolle E, Marion MH, Pollak P. Continuous subcutaneous apomorphine as replacement for levodopa in severe parkinsonian patients after surgery. Lancet 1992; 340: 859-860.
70. Easdown LJ, Tessler MJ, Minuk J. Upper airway involvement in Parkinson's disease resulting in postoperative respiratory failure. Can J Anaesth 1995; 42: 344-347.
71. Onofrj M, Thomas A. Acute akinesia in Parkinson disease. Neurology 2005; 64: 1162-1169.
72. Galvez-Jimenez N, Lang AE. The perioperative management of Parkinson's disease revisited. Neurol Clin 2004; 22: 367-377.
73. Nicholson G, Pereira AC, Hall GM. Parkinson's disease and anaesthesia. Br J Anaesth 2002; 89: 904-916.
74. Doyle SR, Kremer MJ. AANA journal course. Update for nurse anesthetists. Parkinson disease. AANA J 2003; 71: 229-234.
75. Brindle GF. Anesthesia in the patient with parkinsonism. Prim Care 1977; 4: 513-528.
76. Rosin AJ, Devereux D, Eng N, Calne DB. Parkinsonism with 'on-off' phenomena. Intravenous treatment with levodopa after major abdominal surgery. Arch Neurol 1979; 36: 32-34.
77. Liu EH, Choy J, Dhara SS. Persistent perioperative laryngospasm in a patient with Parkinson's disease. Can J Anaesth 1998; 45(5 Pt 1): 495.
78. Galvez-Jimenez N, Lang AE. Perioperative problems in Parkinson's disease and their management: apomorphine with rectal domperidone. Can J Neurol Sci 1996; 23: 198-203.
79. Koganei H, Tanaka S, Iijima K, Horikawa Y, Tanaka O. Postoperative respiratory failure resulting from perioperative withdrawal of antiparkinsonian medications. Masui 1999; 48: 70-72.
80. Bevan DR, Monks PS, Calne DB. Cardiovascular reactions to anaesthesia during treatment with levodopa. Anaesthesia 1973; 28: 29-31.
81. Wullner U, Kassubek J, Odin P, et al. Transdermal rotigotine for the perioperative management of Parkinson's disease. J Neural Transm 2010; 117: 855-859.
82. Korczyn AD, Reichmann H, Boroojerdi B, Hack HJ. Rotigotine transdermal system for perioperative administration. J Neural Transm 2007; 114: 219-221.
83. Merli GJ, Bell RD. Preoperative management of the surgical patient with neurologic disease. Med Clin North Am 1987; 71: 511-527.
84. Sobolewski P. Treatment of Parkinson disease in patients with surgical problems. Neurologia i neurochirurgia polska 2003; 37(Suppl 5): 183-188.
85. Kalenka A, Schwarz A. Anaesthesia and Parkinson's disease: how to manage with new therapies? Curr Opin Anaesthesiol 2009; 22: 419-424.
86. Reed AP, Han DG. Intraoperative exacerbation of Parkinson's disease. Anesth Analg 1992; 75: 850-853.
87. Ngai SH. Parkinsonism, levodopa, and anesthesia. Anesthesiology 1972; 37: 344-351.
88. Horai T, Nishiyama T, Yamamoto H, Hanaoka K. High dose L-dopa infusion during general anesthesia for gastrectomy in a patient with parkinsonism. Masui 2002; 51: 42-45.
89. Frucht SJ. Movement disorder emergencies in the perioperative period. Neurol Clin 2004; 22: 379-387.
90. Spiegel J. Perioperative management of patients with Parkinson's disease. Orthopade 2009; 38: 843-846.
91. Shipton EA, Roelofse JA. Anaesthesia in a patient with Parkinson's disease. A case report. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1984; 65: 304-305.
92. Fujii T, Nakabayashi T, Hashimoto S, Kuwano H. Successful perioperative management of patients with Parkinson's disease following gastrointestinal surgery: report of three cases. Surg Today 2009; 39: 807-810.
93. Mizuno J, Kato S, Watada M, Morita S. Perioperative management of a patient with Parkinson's disease with intravenous infusion of levodopa. Masui 2009; 58: 1286-1289.
94. Toledo LW. The postanesthesia patient with Parkinson's disease. J Post Anesth Nurs 1992; 7: 32-37.
95. O'Brien B, Harmon D. Severe postoperative nausea and vomiting in a parkinsonian patient. Hosp Med 2000; 61: 747.
96. Zuckerman LM. Parkinson's disease and the orthopaedic patient. J Am Acad Orthop Surg 2009; 17: 48-55.
97. Dautzenberg PL, Wouters CJ, Oudejans I, Samson MM. Rivastigmine in prevention of delirium in a 65 years old man with Parkinson's disease. Int J Geriatr Psychiatry 2003; 18: 555-556.
98. Segatore M. Managing the surgical orthopaedic patient with Parkinson's disease. Orthop Nurs 1998; 17: 13-20; quiz 21-12.