메뉴 건너뛰기




Volumn 4, Issue 1, 2011, Pages 55-64

Safety and efficacy of entecavir for the treatment of chronic hepatitis B

Author keywords

Entecavir; Hepatitis b; Therapy

Indexed keywords

ADEFOVIR; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ENTECAVIR; FIALURIDINE; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; NUCLEOSIDE ANALOG; TELBIVUDINE; TENOFOVIR;

EID: 79952674004     PISSN: 11786973     EISSN: None     Source Type: Journal    
DOI: 10.2147/IDR.S4188     Document Type: Review
Times cited : (25)

References (66)
  • 1
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat. 2004;11(2):97-107.
    • (2004) J Viral Hepat , vol.11 , Issue.2 , pp. 97-107
    • Lavanchy, D.1
  • 2
    • 0028945294 scopus 로고
    • Risks of chronicity following acute hepatitis B virus infection: A review
    • Hyams KC. Risks of chronicity following acute hepatitis B virus infection: a review. Clin Infect Dis. 1995;20(4):992-1000.
    • (1995) Clin Infect Dis , vol.20 , Issue.4 , pp. 992-1000
    • Hyams, K.C.1
  • 3
    • 33644506166 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis B virus infection: What we knew in 1981 and what we know in 2005
    • Yim HJ, Lok AS. Natural history of chronic hepatitis B virus infection: what we knew in 1981 and what we know in 2005. Hepatology. 2006; 43(2 Suppl 1):S173-S181.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Yim, H.J.1    Lok, A.S.2
  • 4
    • 33646369150 scopus 로고    scopus 로고
    • Hepatitis B e antigen-negative chronic hepatitis B: Natural history and treatment
    • Hadziyannis SJ, Papatheodoridis GV. Hepatitis B e antigen-negative chronic hepatitis B: natural history and treatment. Semin Liver Dis. 2006; 26(2):130-141.
    • (2006) Semin Liver Dis , vol.26 , Issue.2 , pp. 130-141
    • Hadziyannis, S.J.1    Papatheodoridis, G.V.2
  • 5
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman WF, Jacyna MR, Hadziyannis S, et al. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet. 1989;2(8663):588-591.
    • (1989) Lancet , vol.2 , Issue.8663 , pp. 588-591
    • Carman, W.F.1    Jacyna, M.R.2    Hadziyannis, S.3
  • 6
    • 34247194561 scopus 로고    scopus 로고
    • Management of hepatitis B: Summary of a clinical research workshop
    • Hoofnagle JH, Doo E, Liang TJ, et al. Management of hepatitis B: summary of a clinical research workshop. Hepatology. 2007;45(4):1056-1075.
    • (2007) Hepatology , vol.45 , Issue.4 , pp. 1056-1075
    • Hoofnagle, J.H.1    Doo, E.2    Liang, T.J.3
  • 7
    • 79952644333 scopus 로고    scopus 로고
    • Baraclude Package Insert. Wallingford, CT: Bristol-Myers Squibb, Accessed December 4
    • Baraclude Package Insert. Wallingford, CT: Bristol-Myers Squibb. http://packageinserts.bms.com/pi/pi_baraclude.pdf. Accessed December 4, 2010.
    • (2010)
  • 8
    • 0032907705 scopus 로고    scopus 로고
    • Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus
    • Yamanaka G, Wilson T, Innaimo S, et al. Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus. Antimicrob Agents Chemother. 1999;43(1):190-193.
    • (1999) Antimicrob Agents Chemother , vol.43 , Issue.1 , pp. 190-193
    • Yamanaka, G.1    Wilson, T.2    Innaimo, S.3
  • 9
    • 0031761652 scopus 로고    scopus 로고
    • In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir
    • Seifer M, Hamatake RK, Colonno RJ, Standring DN. In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir. Antimicrob Agents Chemother. 1998;42(12):3200-3208.
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.12 , pp. 3200-3208
    • Seifer, M.1    Hamatake, R.K.2    Colonno, R.J.3    Standring, D.N.4
  • 10
    • 26844500312 scopus 로고    scopus 로고
    • A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients
    • Chang TT, Gish RG, Hadziyannis SJ, et al. A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients. Gastroenterology. 2005;129(4):1198-1209.
    • (2005) Gastroenterology , vol.129 , Issue.4 , pp. 1198-1209
    • Chang, T.T.1    Gish, R.G.2    Hadziyannis, S.J.3
  • 11
    • 0034867425 scopus 로고    scopus 로고
    • Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection
    • De Man RA, Wolters LM, Nevens F, et al. Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection. Hepatology. 2001;34(3):578-582.
    • (2001) Hepatology , vol.34 , Issue.3 , pp. 578-582
    • de Man, R.A.1    Wolters, L.M.2    Nevens, F.3
  • 12
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med. 2006;354(10):1001-1010.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 13
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • Lai CL, Shouval D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2006; 354(10):1011-1020.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1011-1020
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 14
    • 57149089345 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir compared to lamivudine in nucleoside-naive patients with chronic hepatitis B: A randomized double-blind trial in China
    • Yao G, Chen C, Lu W, et al. Efficacy and safety of entecavir compared to lamivudine in nucleoside-naive patients with chronic hepatitis B: a randomized double-blind trial in China. Hepatol Int. 2007;1(3):365-372.
    • (2007) Hepatol Int , vol.1 , Issue.3 , pp. 365-372
    • Yao, G.1    Chen, C.2    Lu, W.3
  • 15
    • 58949087420 scopus 로고    scopus 로고
    • Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir
    • Leung N, Peng CY, Hann HW, et al. Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: a randomized international study of entecavir versus adefovir. Hepatology. 2009;49(1):72-79.
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 72-79
    • Leung, N.1    Peng, C.Y.2    Hann, H.W.3
  • 16
    • 35649020315 scopus 로고    scopus 로고
    • Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B
    • Gish RG, Lok AS, Chang TT, et al. Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B. Gastroenterology. 2007;133(5):1437-1444.
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1437-1444
    • Gish, R.G.1    Lok, A.S.2    Chang, T.T.3
  • 17
    • 58149316191 scopus 로고    scopus 로고
    • Relapse of hepatitis B in HBeAgnegative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy
    • Shouval D, Lai CL, Chang TT, et al. Relapse of hepatitis B in HBeAgnegative chronic hepatitis B patients who discontinued successful entecavir treatment: the case for continuous antiviral therapy. J Hepatol. 2009;50(2):289-295.
    • (2009) J Hepatol , vol.50 , Issue.2 , pp. 289-295
    • Shouval, D.1    Lai, C.L.2    Chang, T.T.3
  • 18
    • 33744531146 scopus 로고    scopus 로고
    • Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B
    • Sherman M, Yurdaydin C, Sollano J, et al. Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B. Gastroenterology. 2006;130(7):2039-2049.
    • (2006) Gastroenterology , vol.130 , Issue.7 , pp. 2039-2049
    • Sherman, M.1    Yurdaydin, C.2    Sollano, J.3
  • 19
    • 56849125493 scopus 로고    scopus 로고
    • Entecavir for the treatment of lamivudinerefractory chronic hepatitis B patients in China
    • Yao G, Zhou X, Xu D, et al. Entecavir for the treatment of lamivudinerefractory chronic hepatitis B patients in China. Hepatol Int. 2007;1(3): 373-381.
    • (2007) Hepatol Int , vol.1 , Issue.3 , pp. 373-381
    • Yao, G.1    Zhou, X.2    Xu, D.3
  • 20
    • 49849099655 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir in lamivudine-refractory patients with chronic hepatitis B: Randomized controlled trial in Japanese patients
    • Suzuki F, Toyoda J, Katano Y, et al. Efficacy and safety of entecavir in lamivudine-refractory patients with chronic hepatitis B: randomized controlled trial in Japanese patients. J Gastroenterol Hepatol. 2008; 23(9):1320-1326.
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.9 , pp. 1320-1326
    • Suzuki, F.1    Toyoda, J.2    Katano, Y.3
  • 21
    • 47149108478 scopus 로고    scopus 로고
    • Entecavir therapy for lamivudine-refractory chronic hepatitis B: Improved virologic, biochemical, and serology outcomes through 96 weeks
    • Sherman M, Yurdaydin C, Simsek H, et al. Entecavir therapy for lamivudine-refractory chronic hepatitis B: improved virologic, biochemical, and serology outcomes through 96 weeks. Hepatology. 2008;48(1):99-108.
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 99-108
    • Sherman, M.1    Yurdaydin, C.2    Simsek, H.3
  • 22
    • 79952676745 scopus 로고    scopus 로고
    • Three years of continuous entecavir treatment in Chinese patients who had previously failed lamivudine: Results from studies ETV-056 and ETV-050 (Abstract)
    • Yao GB, Xu DZ, Ren H, et al. Three years of continuous entecavir treatment in Chinese patients who had previously failed lamivudine: results from studies ETV-056 and ETV-050 (Abstract). Hepatology. 2008;48(Suppl 2):S267.
    • (2008) Hepatology , vol.48 , Issue.SUPPL. 2
    • Yao, G.B.1    Xu, D.Z.2    Ren, H.3
  • 23
    • 70349240414 scopus 로고    scopus 로고
    • Chronic hepatitis B: Update 2009
    • Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology. 2009;50(3):661-662.
    • (2009) Hepatology , vol.50 , Issue.3 , pp. 661-662
    • Lok, A.S.1    McMahon, B.J.2
  • 24
    • 75449107726 scopus 로고    scopus 로고
    • Entecavir treatment for up to 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B
    • Chang TT, Lai CL, Kew Yoon S, et al. Entecavir treatment for up to 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B. Hepatology. 2010;51(2):422-430.
    • (2010) Hepatology , vol.51 , Issue.2 , pp. 422-430
    • Chang, T.T.1    Lai, C.L.2    Kew Yoon, S.3
  • 25
    • 0032499913 scopus 로고    scopus 로고
    • A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group
    • Lai CL, Chien RN, Leung NW, et al. A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. N Engl J Med. 1998;339(2):61-68.
    • (1998) N Engl J Med , vol.339 , Issue.2 , pp. 61-68
    • Lai, C.L.1    Chien, R.N.2    Leung, N.W.3
  • 26
    • 0029591574 scopus 로고
    • A preliminary trial of lamivudine for chronic hepatitis B infection
    • Dienstag JL, Perrillo RP, Schiff ER, et al. A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med. 1995;333(25):1657-1661.
    • (1995) N Engl J Med , vol.333 , Issue.25 , pp. 1657-1661
    • Dienstag, J.L.1    Perrillo, R.P.2    Schiff, E.R.3
  • 27
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med. 2003;348(9):808-816.
    • (2003) N Engl J Med , vol.348 , Issue.9 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 28
    • 33745921497 scopus 로고    scopus 로고
    • A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B
    • Zeng M, Mao Y, Yao G, et al. A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B. Hepatology. 2006;44(1):108-116.
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 108-116
    • Zeng, M.1    Mao, Y.2    Yao, G.3
  • 29
    • 38449093445 scopus 로고    scopus 로고
    • Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: A randomized trial
    • Chan HL, Heathcote EJ, Marcellin P, et al. Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial. Ann Intern Med. 2007;147(11):745-754.
    • (2007) Ann Intern Med , vol.147 , Issue.11 , pp. 745-754
    • Chan, H.L.1    Heathcote, E.J.2    Marcellin, P.3
  • 30
    • 39549113880 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial
    • Hou J, Yin YK, Xu D, et al. Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial. Hepatology. 2008;47(2):447-454.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 447-454
    • Hou, J.1    Yin, Y.K.2    Xu, D.3
  • 31
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med. 2007;357(25):2576-2588.
    • (2007) N Engl J Med , vol.357 , Issue.25 , pp. 2576-2588
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 32
    • 57349095400 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
    • Marcellin P, Heathcote EJ, Buti M, et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med. 2008; 359(23):2442-2455.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2442-2455
    • Marcellin, P.1    Heathcote, E.J.2    Buti, M.3
  • 33
    • 0037468406 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med. 2003;348(9):800-807.
    • (2003) N Engl J Med , vol.348 , Issue.9 , pp. 800-807
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 34
    • 0032783679 scopus 로고    scopus 로고
    • Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
    • Liaw YF, Chien RN, Yeh CT, et al. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology. 1999;30(2):567-572.
    • (1999) Hepatology , vol.30 , Issue.2 , pp. 567-572
    • Liaw, Y.F.1    Chien, R.N.2    Yeh, C.T.3
  • 35
    • 27744510332 scopus 로고    scopus 로고
    • Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation
    • Fung SK, Andreone P, Han SH, et al. Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation. J Hepatol. 2005;43(6):937-943.
    • (2005) J Hepatol , vol.43 , Issue.6 , pp. 937-943
    • Fung, S.K.1    Andreone, P.2    Han, S.H.3
  • 36
    • 0034993211 scopus 로고    scopus 로고
    • Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after 3 years of therapy
    • Leung NW, Lai CL, Chang TT, et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy. Hepatology. 2001;33(6):1527-1532.
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1527-1532
    • Leung, N.W.1    Lai, C.L.2    Chang, T.T.3
  • 37
    • 70350133508 scopus 로고    scopus 로고
    • Entecavir maintains a high genetic barrier to HBV resistance through 6 years in naive patients (Abstract)
    • Tenney D, Pokornowski K, Rose RE, et al. Entecavir maintains a high genetic barrier to HBV resistance through 6 years in naive patients (Abstract). Hepatology. 2009;50(Suppl 2):S10.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 2
    • Tenney, D.1    Pokornowski, K.2    Rose, R.E.3
  • 38
    • 66149115173 scopus 로고    scopus 로고
    • Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naive patients is rare through 5 years of therapy
    • Tenney DJ, Rose RE, Baldick CJ, et al. Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naive patients is rare through 5 years of therapy. Hepatology. 2009;49(5):1503-1514.
    • (2009) Hepatology , vol.49 , Issue.5 , pp. 1503-1514
    • Tenney, D.J.1    Rose, R.E.2    Baldick, C.J.3
  • 39
    • 21244455293 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med. 2005;352(26):2673-2681.
    • (2005) N Engl J Med , vol.352 , Issue.26 , pp. 2673-2681
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 40
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology. 2006;131(6):1743-1751.
    • (2006) Gastroenterology , vol.131 , Issue.6 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 41
    • 79952676416 scopus 로고    scopus 로고
    • No resistance to tenofovir disoproxil fumarate (TDF) detected following 192 weeks of treatment in subjects mono-infected with chronic hepatitis B virus (Abstract)
    • Snow-Lampart A, Kitrinos K, Chappell BJ, et al. No resistance to tenofovir disoproxil fumarate (TDF) detected following 192 weeks of treatment in subjects mono-infected with chronic hepatitis B virus (Abstract). Hepatology. 2010;52(Suppl 1):977A.
    • (2010) Hepatology , vol.52 , Issue.SUPPL. 1
    • Snow-Lampart, A.1    Kitrinos, K.2    Chappell, B.J.3
  • 42
    • 58649096155 scopus 로고    scopus 로고
    • 2-Year GLOBE trial results: Telbivudine is superior to lamivudine in patients with chronic hepatitis B
    • Liaw YF, Gane E, Leung N, et al. 2-Year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology. 2009;136(2):486-495.
    • (2009) Gastroenterology , vol.136 , Issue.2 , pp. 486-495
    • Liaw, Y.F.1    Gane, E.2    Leung, N.3
  • 43
    • 0029817898 scopus 로고    scopus 로고
    • Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo
    • Tipples GA, Ma MM, Fischer KP, et al. Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology. 1996;24(3):714-717.
    • (1996) Hepatology , vol.24 , Issue.3 , pp. 714-717
    • Tipples, G.A.1    Ma, M.M.2    Fischer, K.P.3
  • 44
    • 0041853784 scopus 로고    scopus 로고
    • Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase
    • Angus P, Vaughan R, Xiong S, et al. Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase. Gastroenterology. 2003;125(2):292-297.
    • (2003) Gastroenterology , vol.125 , Issue.2 , pp. 292-297
    • Angus, P.1    Vaughan, R.2    Xiong, S.3
  • 45
    • 34548349001 scopus 로고    scopus 로고
    • Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials
    • Borroto-Esoda K, Miller MD, Arterburn S. Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials. J Hepatol. 2007;47(4): 492-498.
    • (2007) J Hepatol , vol.47 , Issue.4 , pp. 492-498
    • Borroto-Esoda, K.1    Miller, M.D.2    Arterburn, S.3
  • 46
    • 4344627233 scopus 로고    scopus 로고
    • Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine
    • Tenney DJ, Levine SM, Rose RE, et al. Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine. Antimicrob Agents Chemother. 2004;48(9):3498-3507.
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.9 , pp. 3498-3507
    • Tenney, D.J.1    Levine, S.M.2    Rose, R.E.3
  • 47
    • 43049174567 scopus 로고    scopus 로고
    • Hepatitis B virus quasispecies susceptibility to entecavir confirms the relationship between genotypic resistance and patient virologic response
    • Baldick CJ, Eggers BJ, Fang J, et al. Hepatitis B virus quasispecies susceptibility to entecavir confirms the relationship between genotypic resistance and patient virologic response. J Hepatol. 2008;48(6): 895-902.
    • (2008) J Hepatol , vol.48 , Issue.6 , pp. 895-902
    • Baldick, C.J.1    Eggers, B.J.2    Fang, J.3
  • 48
    • 55349135866 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir in patients with chronic hepatitis B and advanced hepatic fibrosis or cirrhosis
    • Schiff E, Simsek H, Lee WM, et al. Efficacy and safety of entecavir in patients with chronic hepatitis B and advanced hepatic fibrosis or cirrhosis. Am J Gastroenterol. 2008;103(11):2776-2783.
    • (2008) Am J Gastroenterol , vol.103 , Issue.11 , pp. 2776-2783
    • Schiff, E.1    Simsek, H.2    Lee, W.M.3
  • 49
    • 75349107764 scopus 로고    scopus 로고
    • Efficacy of entecavir in treatment-naive patients with hepatitis B virus-related decompensated cirrhosis
    • Shim JH, Lee HC, Kim KM, et al. Efficacy of entecavir in treatment-naive patients with hepatitis B virus-related decompensated cirrhosis. J Hepatol. 2010;52(2):176-182.
    • (2010) J Hepatol , vol.52 , Issue.2 , pp. 176-182
    • Shim, J.H.1    Lee, H.C.2    Kim, K.M.3
  • 50
    • 75449103627 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir versus adefovir in chronic hepatitis B patients with evidence of hepatic decompensation (Abstract)
    • Liaw YF, Raptopoulou-Gigi M, Chienquer H, et al. Efficacy and safety of entecavir versus adefovir in chronic hepatitis B patients with evidence of hepatic decompensation (Abstract). Hepatology. 2009;50(Suppl 4): 505A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 4
    • Liaw, Y.F.1    Raptopoulou-Gigi, M.2    Chienquer, H.3
  • 51
    • 70449105201 scopus 로고    scopus 로고
    • The role of entecavir in preventing hepatitis B recurrence after liver transplantation
    • Xi ZF, Xia Q, Zhang JJ, et al. The role of entecavir in preventing hepatitis B recurrence after liver transplantation. J Dig Dis. 2009;10(4): 321-327.
    • (2009) J Dig Dis , vol.10 , Issue.4 , pp. 321-327
    • Xi, Z.F.1    Xia, Q.2    Zhang, J.J.3
  • 52
    • 63849149651 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir for chronic HBV in HIV/HBV coinfected patients receiving lamivudine as part of antiretroviral therapy
    • Pessoa MG, Gazzard B, Huang AK, et al. Efficacy and safety of entecavir for chronic HBV in HIV/HBV coinfected patients receiving lamivudine as part of antiretroviral therapy. AIDS. 2008;22(14):1779-1787.
    • (2008) AIDS , vol.22 , Issue.14 , pp. 1779-1787
    • Pessoa, M.G.1    Gazzard, B.2    Huang, A.K.3
  • 53
    • 34250722018 scopus 로고    scopus 로고
    • The HBV drug entecavir: Effects on HIV-1 replication and resistance
    • McMahon MA, Jilek BL, Brennan TP, et al. The HBV drug entecavir: effects on HIV-1 replication and resistance. N Engl J Med. 2007; 356(25):2614-2621.
    • (2007) N Engl J Med , vol.356 , Issue.25 , pp. 2614-2621
    • McMahon, M.A.1    Jilek, B.L.2    Brennan, T.P.3
  • 54
    • 43249116834 scopus 로고    scopus 로고
    • The anti-HIV activity of entecavir: A multicentre evaluation of lamivudine-experienced and lamivudine-naive patients
    • Sasadeusz J, Audsley J, Mijch A, et al. The anti-HIV activity of entecavir: a multicentre evaluation of lamivudine-experienced and lamivudine-naive patients. AIDS. 2008;22(8):947-955.
    • (2008) AIDS , vol.22 , Issue.8 , pp. 947-955
    • Sasadeusz, J.1    Audsley, J.2    Mijch, A.3
  • 55
    • 84989805325 scopus 로고    scopus 로고
    • Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents
    • Department of Health and Human Services, December 1, Accessed December 12, 2010
    • Department of Health and Human Services. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Office of AIDS Research Advisory Council (OARAC). December 1, 2009. http://aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL.pdf. Accessed December 12, 2010.
    • (2009) Office of AIDS Research Advisory Council (OARAC)
  • 56
    • 48949097660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel
    • Hammer SM, Eron JJ Jr, Reiss P, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA. 2008;300(5):555-570.
    • (2008) JAMA , vol.300 , Issue.5 , pp. 555-570
    • Hammer, S.M.1    Eron Jr., J.J.2    Reiss, P.3
  • 57
    • 0028817865 scopus 로고
    • Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B
    • McKenzie R, Fried MW, Sallie R, et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med. 1995;333(17):1099-1105.
    • (1995) N Engl J Med , vol.333 , Issue.17 , pp. 1099-1105
    • McKenzie, R.1    Fried, M.W.2    Sallie, R.3
  • 58
    • 0032189850 scopus 로고    scopus 로고
    • Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway
    • Brinkman K, ter Hofstede HJ, Burger DM, et al. Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as common pathway. AIDS. 1998;12(14):1735-1744.
    • (1998) AIDS , vol.12 , Issue.14 , pp. 1735-1744
    • Brinkman, K.1    ter Hofstede, H.J.2    Burger, D.M.3
  • 59
    • 0029866581 scopus 로고    scopus 로고
    • Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU)
    • Colacino JM. Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU). Antiviral Res. 1996;29(2-3):125-139.
    • (1996) Antiviral Res , vol.29 , Issue.2-3 , pp. 125-139
    • Colacino, J.M.1
  • 60
    • 0242363266 scopus 로고    scopus 로고
    • Mitochondrial toxicity of NRTI antiviral drugs: An integrated cellular perspective
    • Lewis W, Day BJ, Copeland WC. Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. Nat Rev Drug Discov. 2003;2(10):812-822.
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.10 , pp. 812-822
    • Lewis, W.1    Day, B.J.2    Copeland, W.C.3
  • 61
    • 38649121164 scopus 로고    scopus 로고
    • Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition
    • Mazzucco CE, Hamatake RK, Colonno RJ, Tenney DJ. Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition. Antimicrob Agents Chemother. 2008;52(2):598-605.
    • (2008) Antimicrob Agents Chemother , vol.52 , Issue.2 , pp. 598-605
    • Mazzucco, C.E.1    Hamatake, R.K.2    Colonno, R.J.3    Tenney, D.J.4
  • 62
    • 73149085984 scopus 로고    scopus 로고
    • Severe lactic acidosis during treatment of chronic hepatitis B with entecavir in patients with impaired liver function
    • Lange CM, Bojunga J, Hofmann WP, et al. Severe lactic acidosis during treatment of chronic hepatitis B with entecavir in patients with impaired liver function. Hepatology. 2009;50(6):2001-2006.
    • (2009) Hepatology , vol.50 , Issue.6 , pp. 2001-2006
    • Lange, C.M.1    Bojunga, J.2    Hofmann, W.P.3
  • 63
    • 73149117465 scopus 로고    scopus 로고
    • Fatal lactic acidosis associated with the use of combination oral medications to treat reactivation of hepatitis B
    • Cohen SM, Levy RM, Jovanovich JF, Ahn J. Fatal lactic acidosis associated with the use of combination oral medications to treat reactivation of hepatitis B. J Clin Gastroenterol. 2009;43(10):1008-1010.
    • (2009) J Clin Gastroenterol , vol.43 , Issue.10 , pp. 1008-1010
    • Cohen, S.M.1    Levy, R.M.2    Jovanovich, J.F.3    Ahn, J.4
  • 64
    • 58149296156 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of chronic hepatitis B
    • European Association for the Study of the Liver
    • European Association for the Study of the Liver. EASL clinical practice guidelines: management of chronic hepatitis B. J Hepatol. 2009;50(2):227-242.
    • (2009) J Hepatol , vol.50 , Issue.2 , pp. 227-242
  • 65
    • 51049107683 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2008 update
    • Liaw YF, Leung N, Kao JH, et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int. 2008;2:263-283.
    • (2008) Hepatol Int , vol.2 , pp. 263-283
    • Liaw, Y.F.1    Leung, N.2    Kao, J.H.3
  • 66
    • 57149091722 scopus 로고    scopus 로고
    • A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update
    • Keeffe EB, Dieterich DT, Han SH, et al. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clin Gastroenterol Hepatol. 2008;6(12):1315-1341.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , Issue.12 , pp. 1315-1341
    • Keeffe, E.B.1    Dieterich, D.T.2    Han, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.