Postnatal variations in blood free and acylcarnitines

Journal of Clinical Laboratory Analysis

Volumn 25, Issue 2, 2011, Pages 126-129

  De, Tanima ^a   Kruthika Vinod, T P ^a   Nagaraja, Dindagur ^a   Christopher, Rita ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Acylcarnitines; Free carnitine; Newborns; Tandem mass spectrometry

Indexed keywords

ACYLCARNITINE; CARNITINE; LONG CHAIN FATTY ACID; MEDIUM CHAIN FATTY ACID; SHORT CHAIN FATTY ACID;

ACIDEMIA; ARTICLE; BLOOD SAMPLING; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIAGNOSTIC ERROR; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; ELECTROSPRAY MASS SPECTROMETRY; FATTY ACID OXIDATION; FEMALE; HUMAN; INDIA; INFANT; NEWBORN; NORMAL HUMAN; PERINATAL PERIOD; RISK ASSESSMENT; SEX DIFFERENCE; TANDEM MASS SPECTROMETRY;

CARNITINE; FEMALE; GENETIC VARIATION; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MALE; METABOLISM, INBORN ERRORS; NEONATAL SCREENING; REFERENCE VALUES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 79952669937     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20445     Document Type: Article

References (10)

1. Sewell AC, Bohles HJ. Acylcarnitines in intermediary metabolism. Eur J Pediatr 1995;154:871-877.
2. Rashed MS. Clinical applications of tandem mass spectrometry: Ten years of diagnosis and screening for inherited metabolic diseases. J Chromatogr B Biomed Sci Appl 2001;758:27-48.
3. Chace DH, Pons R, Chiriboga CA, et al. Neonatal blood carnitine concentrations: Normative data by electrospray tandem mass spectometry. Pediatr Res 2003;53:823-829.
4. Verma IC, Bijarnia S. The burden of genetic disorders in India and a framework for community control. Community Genet 2002;5:192-196.
5. Shenai JP, Borum PR, Mohan P, Donlevy SC. Carnitine status at birth of newborn infants of varying gestation. Pediatr Res 1983;17:579-582.
6. Schmidt-Sommerfeld E, Penn D, Sodha RJ, Progler M, Novak M, Schneider H. Transfer and metabolism of carnitine and carnitine esters in the in vitro perfused human placenta. Pediatr Res 1985;19:700-706.
7. Campoy C, Bayes R, Peinado JM, Rivero M, Lopez C, Molina-Font JA. Evaluation of carnitine nutritional status in full-term newborn infants. Early Hum Dev 1998;53:S149-S164.
8. de Sousa C, English NR, Stacey TE, Chalmers RA. Measurement of L-carnitine and acylcarnitines in body fluids and tissues in children and in adults. Clin Chim Acta 1990;187:317-328.
9. Meyburg J, Schulze A, Kohlmueller D, Linderkamp O, Mayatepek E. Postnatal changes in neonatal acylcarnitine profile. Pediatr Res 2001;49:125-129.
10. Cavedon CT, Bourdoux P, Mertens K, et al. Age-related variations in acylcarnitine and free carnitine concentrations measured by tandem mass spectrometry. Clin Chem 2005;51:745-752.