메뉴 건너뛰기




Volumn 6, Issue 3, 2011, Pages

Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CYCLOPHOSPHAMIDE; GEMCITABINE; GLYCOPROTEIN P 15095; INTERLEUKIN 8; NEUTRALIZING ANTIBODY; CHEMOTACTIC FACTOR;

EID: 79952659848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017922     Document Type: Article
Times cited : (35)

References (56)
  • 1
    • 22044438503 scopus 로고    scopus 로고
    • Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8
    • Feijoo E, Alfaro C, Mazzolini G, Serra P, Penuelas I, et al. (2005) Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8. Int J Cancer 116: 275-281.
    • (2005) Int J Cancer , vol.116 , pp. 275-281
    • Feijoo, E.1    Alfaro, C.2    Mazzolini, G.3    Serra, P.4    Penuelas, I.5
  • 2
    • 20044396550 scopus 로고    scopus 로고
    • Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
    • Mazzolini G, Alfaro C, Sangro B, Feijoo E, Ruiz J, et al. (2005) Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas. J Clin Oncol 23: 999-1010.
    • (2005) J Clin Oncol , vol.23 , pp. 999-1010
    • Mazzolini, G.1    Alfaro, C.2    Sangro, B.3    Feijoo, E.4    Ruiz, J.5
  • 3
    • 0034849755 scopus 로고    scopus 로고
    • Interleukin-8 and human cancer biology
    • Xie K, (2001) Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12: 375-391.
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 375-391
    • Xie, K.1
  • 4
    • 0032903573 scopus 로고    scopus 로고
    • Distinct patterns and kinetics of chemokine production regulate dendritic cell function
    • Sallusto F, Palermo B, Lenig D, Miettinen M, Matikainen S, et al. (1999) Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur J Immunol 29: 1617-1625.
    • (1999) Eur J Immunol , vol.29 , pp. 1617-1625
    • Sallusto, F.1    Palermo, B.2    Lenig, D.3    Miettinen, M.4    Matikainen, S.5
  • 5
    • 0031571280 scopus 로고    scopus 로고
    • Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines
    • Sozzani S, Luini W, Borsatti A, Polentarutti N, Zhou D, et al. (1997) Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J Immunol 159: 1993-2000.
    • (1997) J Immunol , vol.159 , pp. 1993-2000
    • Sozzani, S.1    Luini, W.2    Borsatti, A.3    Polentarutti, N.4    Zhou, D.5
  • 6
    • 34249658464 scopus 로고    scopus 로고
    • Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8
    • Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, et al. (2007) Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem 282: 11658-11666.
    • (2007) J Biol Chem , vol.282 , pp. 11658-11666
    • Fan, X.1    Patera, A.C.2    Pong-Kennedy, A.3    Deno, G.4    Gonsiorek, W.5
  • 7
    • 0033557170 scopus 로고    scopus 로고
    • Mobilizing dendritic cells for tolerance, priming, and chronic inflammation
    • Sallusto F, Lanzavecchia A, (1999) Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J Exp Med 189: 611-614.
    • (1999) J Exp Med , vol.189 , pp. 611-614
    • Sallusto, F.1    Lanzavecchia, A.2
  • 9
    • 0042922810 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
    • MartIn-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, et al. (2003) Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 198: 615-621.
    • (2003) J Exp Med , vol.198 , pp. 615-621
    • MartIn-Fontecha, A.1    Sebastiani, S.2    Hopken, U.E.3    Uguccioni, M.4    Lipp, M.5
  • 11
    • 19944429072 scopus 로고    scopus 로고
    • Intratumoural administration of dendritic cells: hostile environment and help by gene therapy
    • Huarte E, Tirapu I, Arina A, Vera M, Alfaro C, et al. (2005) Intratumoural administration of dendritic cells: hostile environment and help by gene therapy. Expert Opin Biol Ther 5: 7-22.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 7-22
    • Huarte, E.1    Tirapu, I.2    Arina, A.3    Vera, M.4    Alfaro, C.5
  • 13
    • 58149232586 scopus 로고    scopus 로고
    • The interleukin-8 pathway in cancer
    • Waugh DJ, Wilson C, (2008) The interleukin-8 pathway in cancer. Clin Cancer Res 14: 6735-6741.
    • (2008) Clin Cancer Res , vol.14 , pp. 6735-6741
    • Waugh, D.J.1    Wilson, C.2
  • 14
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C, Muthana M, Coffelt SB, Lewis CE, (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 8: 618-631.
    • (2008) Nat Rev Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 15
    • 0345735832 scopus 로고    scopus 로고
    • IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor
    • Schraufstatter IU, Trieu K, Zhao M, Rose DM, Terkeltaub RA, et al. (2003) IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor. J Immunol 171: 6714-6722.
    • (2003) J Immunol , vol.171 , pp. 6714-6722
    • Schraufstatter, I.U.1    Trieu, K.2    Zhao, M.3    Rose, D.M.4    Terkeltaub, R.A.5
  • 16
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin WW, Karin M, (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183.
    • (2007) J Clin Invest , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 17
    • 43549109264 scopus 로고    scopus 로고
    • The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment
    • Rolny C, Capparuccia L, Casazza A, Mazzone M, Vallario A, et al. (2008) The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment. J Exp Med 205: 1155-1171.
    • (2008) J Exp Med , vol.205 , pp. 1155-1171
    • Rolny, C.1    Capparuccia, L.2    Casazza, A.3    Mazzone, M.4    Vallario, A.5
  • 18
    • 0028027039 scopus 로고
    • Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis
    • Ueda T, Shimada E, Urakawa T, (1994) Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis. J Gastroenterol 29: 423-429.
    • (1994) J Gastroenterol , vol.29 , pp. 423-429
    • Ueda, T.1    Shimada, E.2    Urakawa, T.3
  • 19
    • 76249133170 scopus 로고    scopus 로고
    • Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma
    • Huang D, Ding Y, Zhou M, Rini BI, Petillo D, et al. Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res 70: 1063-1071.
    • Cancer Res , vol.70 , pp. 1063-1071
    • Huang, D.1    Ding, Y.2    Zhou, M.3    Rini, B.I.4    Petillo, D.5
  • 20
    • 0028353278 scopus 로고
    • Interleukin-8 and related chemotactic cytokines. The Giles Filley Lecture
    • Baggiolini M, Moser B, Clark-Lewis I, (1994) Interleukin-8 and related chemotactic cytokines. The Giles Filley Lecture. Chest 105: 95S-98S.
    • (1994) Chest , vol.105
    • Baggiolini, M.1    Moser, B.2    Clark-Lewis, I.3
  • 21
    • 0033823676 scopus 로고    scopus 로고
    • Chemokines in inflammation and immunity
    • Baggiolini M, Loetscher P, (2000) Chemokines in inflammation and immunity. Immunol Today 21: 418-420.
    • (2000) Immunol Today , vol.21 , pp. 418-420
    • Baggiolini, M.1    Loetscher, P.2
  • 22
    • 70149115487 scopus 로고    scopus 로고
    • The functional significance behind expressing two IL-8 receptor types on PMN
    • Stillie R, Farooq SM, Gordon JR, Stadnyk AW, (2009) The functional significance behind expressing two IL-8 receptor types on PMN. J Leukoc Biol 86: 529-543.
    • (2009) J Leukoc Biol , vol.86 , pp. 529-543
    • Stillie, R.1    Farooq, S.M.2    Gordon, J.R.3    Stadnyk, A.W.4
  • 23
    • 0033930588 scopus 로고    scopus 로고
    • Feeding dendritic cells with tumor antigens: self-service buffet or a la carte?
    • Melero I, Vile RG, Colombo MP, (2000) Feeding dendritic cells with tumor antigens: self-service buffet or a la carte? Gene Ther 7: 1167-1170.
    • (2000) Gene Ther , vol.7 , pp. 1167-1170
    • Melero, I.1    Vile, R.G.2    Colombo, M.P.3
  • 24
    • 34247363968 scopus 로고    scopus 로고
    • Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma
    • Guo J, Zhu J, Sheng X, Wang X, Qu L, et al. (2007) Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma. Int J Cancer 120: 2418-2425.
    • (2007) Int J Cancer , vol.120 , pp. 2418-2425
    • Guo, J.1    Zhu, J.2    Sheng, X.3    Wang, X.4    Qu, L.5
  • 25
    • 0034672104 scopus 로고    scopus 로고
    • Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer
    • Triozzi PL, Khurram R, Aldrich WA, Walker MJ, Kim JA, et al. (2000) Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer. Cancer 89: 2646-2654.
    • (2000) Cancer , vol.89 , pp. 2646-2654
    • Triozzi, P.L.1    Khurram, R.2    Aldrich, W.A.3    Walker, M.J.4    Kim, J.A.5
  • 26
    • 63949087054 scopus 로고    scopus 로고
    • Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
    • Alfaro C, Suarez N, Gonzalez A, Solano S, Erro L, et al. (2009) Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes. Br J Cancer 100: 1111-1119.
    • (2009) Br J Cancer , vol.100 , pp. 1111-1119
    • Alfaro, C.1    Suarez, N.2    Gonzalez, A.3    Solano, S.4    Erro, L.5
  • 27
    • 65249088470 scopus 로고    scopus 로고
    • Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
    • Verdijk P, Aarntzen EH, Lesterhuis WJ, Boullart AC, Kok E, et al. (2009) Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res 15: 2531-2540.
    • (2009) Clin Cancer Res , vol.15 , pp. 2531-2540
    • Verdijk, P.1    Aarntzen, E.H.2    Lesterhuis, W.J.3    Boullart, A.C.4    Kok, E.5
  • 28
    • 27944504770 scopus 로고    scopus 로고
    • Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
    • de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, et al. (2005) Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 23: 1407-1413.
    • (2005) Nat Biotechnol , vol.23 , pp. 1407-1413
    • de Vries, I.J.1    Lesterhuis, W.J.2    Barentsz, J.O.3    Verdijk, P.4    van Krieken, J.H.5
  • 29
    • 51349123892 scopus 로고    scopus 로고
    • Cancer immunotherapy by dendritic cells
    • Melief CJ, (2008) Cancer immunotherapy by dendritic cells. Immunity 29: 372-383.
    • (2008) Immunity , vol.29 , pp. 372-383
    • Melief, C.J.1
  • 30
    • 29144489464 scopus 로고    scopus 로고
    • Filter Buffy Coats (FBC): a source of peripheral blood leukocytes recovered from leukocyte depletion filters
    • Meyer TP, Zehnter I, Hofmann B, Zaisserer J, Burkhart J, et al. (2005) Filter Buffy Coats (FBC): a source of peripheral blood leukocytes recovered from leukocyte depletion filters. J Immunol Methods 307: 150-166.
    • (2005) J Immunol Methods , vol.307 , pp. 150-166
    • Meyer, T.P.1    Zehnter, I.2    Hofmann, B.3    Zaisserer, J.4    Burkhart, J.5
  • 31
    • 0035214416 scopus 로고    scopus 로고
    • Metronomic scheduling: the future of chemotherapy?
    • Gasparini G, (2001) Metronomic scheduling: the future of chemotherapy? Lancet Oncol 2: 733-740.
    • (2001) Lancet Oncol , vol.2 , pp. 733-740
    • Gasparini, G.1
  • 32
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • Ghiringhelli F, Menard C, Puig PE, Ladoire S, Roux S, et al. (2007) Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 56: 641-648.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.E.3    Ladoire, S.4    Roux, S.5
  • 33
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F, (2004) Cancer and the chemokine network. Nat Rev Cancer 4: 540-550.
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 34
    • 0035209339 scopus 로고    scopus 로고
    • Imaging of human infection with (131)I-labeled recombinant human interleukin-8
    • Gross MD, Shapiro B, Fig LM, Steventon R, Skinner RW, et al. (2001) Imaging of human infection with (131)I-labeled recombinant human interleukin-8. J Nucl Med 42: 1656-1659.
    • (2001) J Nucl Med , vol.42 , pp. 1656-1659
    • Gross, M.D.1    Shapiro, B.2    Fig, L.M.3    Steventon, R.4    Skinner, R.W.5
  • 35
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi D, Zlotnik A, (2000) The biology of chemokines and their receptors. Annu Rev Immunol 18: 217-242.
    • (2000) Annu Rev Immunol , vol.18 , pp. 217-242
    • Rossi, D.1    Zlotnik, A.2
  • 36
    • 33644520242 scopus 로고    scopus 로고
    • Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma
    • Tirapu I, Huarte E, Guiducci C, Arina A, Zaratiegui M, et al. (2006) Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma. Cancer Res 66: 2442-2450.
    • (2006) Cancer Res , vol.66 , pp. 2442-2450
    • Tirapu, I.1    Huarte, E.2    Guiducci, C.3    Arina, A.4    Zaratiegui, M.5
  • 37
  • 38
    • 44349150012 scopus 로고    scopus 로고
    • Inhibitory B7-family molecules in the tumour microenvironment
    • Zou W, Chen L, (2008) Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol 8: 467-477.
    • (2008) Nat Rev Immunol , vol.8 , pp. 467-477
    • Zou, W.1    Chen, L.2
  • 39
    • 79961102493 scopus 로고    scopus 로고
    • Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
    • Suarez N, Alfaro C, Dubrot J, Palazon A, Bolanos E, et al. Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo. Int J Cancer.
    • Int J Cancer
    • Suarez, N.1    Alfaro, C.2    Dubrot, J.3    Palazon, A.4    Bolanos, E.5
  • 41
    • 33748162638 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells: cytokine modulation comes of age
    • Rutella S, Danese S, Leone G, (2006) Tolerogenic dendritic cells: cytokine modulation comes of age. Blood 108: 1435-1440.
    • (2006) Blood , vol.108 , pp. 1435-1440
    • Rutella, S.1    Danese, S.2    Leone, G.3
  • 42
    • 4644345036 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A
    • Epub 2004 Aug 2029
    • Conejo-Garcia JR, Benencia F, Courreges MC, Kang E, Mohamed-Hadley A, et al. (2004) Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nat Med 10: 950-958 Epub 2004 Aug 2029.
    • (2004) Nat Med , vol.10 , pp. 950-958
    • Conejo-Garcia, J.R.1    Benencia, F.2    Courreges, M.C.3    Kang, E.4    Mohamed-Hadley, A.5
  • 43
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR, Cunningham HT, Meny GM, et al. (1996) Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2: 1096-1103.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5
  • 44
    • 34249000341 scopus 로고    scopus 로고
    • Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development
    • Aspord C, Pedroza-Gonzalez A, Gallegos M, Tindle S, Burton EC, et al. (2007) Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development. J Exp Med 204: 1037-1047.
    • (2007) J Exp Med , vol.204 , pp. 1037-1047
    • Aspord, C.1    Pedroza-Gonzalez, A.2    Gallegos, M.3    Tindle, S.4    Burton, E.C.5
  • 46
    • 0033571785 scopus 로고    scopus 로고
    • In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
    • Bell D, Chomarat P, Broyles D, Netto G, Harb GM, et al. (1999) In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 190: 1417-1426.
    • (1999) J Exp Med , vol.190 , pp. 1417-1426
    • Bell, D.1    Chomarat, P.2    Broyles, D.3    Netto, G.4    Harb, G.M.5
  • 47
    • 0034234661 scopus 로고    scopus 로고
    • Dendritic cells modified to express CD40 ligand elicit therapeutic immunity against preexisting murine tumors
    • Kikuchi T, Moore MA, Crystal RG, (2000) Dendritic cells modified to express CD40 ligand elicit therapeutic immunity against preexisting murine tumors. Blood 96: 91-99.
    • (2000) Blood , vol.96 , pp. 91-99
    • Kikuchi, T.1    Moore, M.A.2    Crystal, R.G.3
  • 48
    • 84941944867 scopus 로고    scopus 로고
    • Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication
    • Miller PW, Sharma S, Stolina M, Butterfield LH, Luo J, et al. (2000) Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication. Hum Gene Ther 11: 53-65.
    • (2000) Hum Gene Ther , vol.11 , pp. 53-65
    • Miller, P.W.1    Sharma, S.2    Stolina, M.3    Butterfield, L.H.4    Luo, J.5
  • 49
    • 0033566984 scopus 로고    scopus 로고
    • Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12
    • Nishioka Y, Hirao M, Robbins PD, Lotze MT, Tahara H, (1999) Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12. Cancer Res 59: 4035-4041.
    • (1999) Cancer Res , vol.59 , pp. 4035-4041
    • Nishioka, Y.1    Hirao, M.2    Robbins, P.D.3    Lotze, M.T.4    Tahara, H.5
  • 50
    • 11144356776 scopus 로고    scopus 로고
    • Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens
    • Tirapu I, Arina A, Mazzolini G, Duarte M, Alfaro C, et al. (2004) Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens. Int J Cancer 110: 51-60.
    • (2004) Int J Cancer , vol.110 , pp. 51-60
    • Tirapu, I.1    Arina, A.2    Mazzolini, G.3    Duarte, M.4    Alfaro, C.5
  • 51
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S, (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9: 162-174.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 52
    • 18244389671 scopus 로고    scopus 로고
    • Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN
    • van Gisbergen KP, Sanchez-Hernandez M, Geijtenbeek TB, van Kooyk Y, (2005) Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. J Exp Med 201: 1281-1292.
    • (2005) J Exp Med , vol.201 , pp. 1281-1292
    • van Gisbergen, K.P.1    Sanchez-Hernandez, M.2    Geijtenbeek, T.B.3    van Kooyk, Y.4
  • 53
    • 33646433944 scopus 로고    scopus 로고
    • Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena
    • Melero I, Arina A, Murillo O, Dubrot J, Alfaro C, et al. (2006) Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena. Clin Cancer Res 12: 2385-2389.
    • (2006) Clin Cancer Res , vol.12 , pp. 2385-2389
    • Melero, I.1    Arina, A.2    Murillo, O.3    Dubrot, J.4    Alfaro, C.5
  • 54
    • 70349243743 scopus 로고    scopus 로고
    • In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
    • Murillo O, Dubrot J, Palazon A, Arina A, Azpilikueta A, et al. (2009) In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb. Eur J Immunol 39: 2424-2436.
    • (2009) Eur J Immunol , vol.39 , pp. 2424-2436
    • Murillo, O.1    Dubrot, J.2    Palazon, A.3    Arina, A.4    Azpilikueta, A.5
  • 55
    • 0032844949 scopus 로고    scopus 로고
    • Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas
    • Melero I, Duarte M, Ruiz J, Sangro B, Galofre J, et al. (1999) Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas. Gene Ther 6: 1779-1784.
    • (1999) Gene Ther , vol.6 , pp. 1779-1784
    • Melero, I.1    Duarte, M.2    Ruiz, J.3    Sangro, B.4    Galofre, J.5
  • 56
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
    • Barnden MJ, Allison J, Heath WR, Carbone FR, (1998) Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 76: 34-40.
    • (1998) Immunol Cell Biol , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.