The Efficacy of Costus igneus Rhizome on Carbohydrate Metabolic, Hepatoproductive and Antioxidative Enzymes in Streptozotocin-induced Diabetic Rats

Journal of Health Science

Volumn 57, Issue 1, 2011, Pages 37-46

  Kalailingam, Pazhanichamy ^a   Devi Sekar, Aiswarya ^a   Clement Samuel, Jeba Samuel ^a   Gandhirajan, Priya ^a   Govindaraju, Yogha ^a   Kesavan, Manjula ^a   Kaliaperumal, Rajendran ^a   Shanmugam, Kumaran ^a   Tamilmani, Eevera ^b  

^a PERIYAR MANIAMMAI UNIVERSITY   (India)

^b TAMIL NADU AGRICULTURAL UNIVERSITY   (India)

Author keywords

Costus igneus; Diosgenin; Glycolytic enzyme; Quercetin

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CATALASE; COSTUS IGNEUS EXTRACT; DIOSGENIN; FRUCTOSE BISPHOSPHATASE; GLIBENCLAMIDE; GLUCOKINASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDE; PLANT EXTRACT; QUERCETIN; SUPEROXIDE DISMUTASE; THIOL GROUP; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; COSTUS; COSTUS IGNEUS; DIABETES MELLITUS; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ASSAY; ENZYME BLOOD LEVEL; ENZYME SYNTHESIS; GLUCONEOGENESIS; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PHYTOCHEMISTRY; RAT; SINGLE DRUG DOSE; STREPTOZOCIN DIABETES; TREATMENT DURATION;

ANIMALIA; COSTUS; RATTUS;

EID: 79952610726     PISSN: 13449702     EISSN: 13475207     Source Type: Journal    
DOI: 10.1248/jhs.57.37     Document Type: Article

References (43)

1. Pavana, P., Sethupathy, S., Santha, K. and Manoharan, S. (2009) Effects of Tephrosia purpurea aqueous seed extract on blood glucose and antioxi- dant enzyme activities in streptozotocin induced di- abetic rats. Afr. J. Trad. CAM, 6, 78-86.
2. Bhor, V. M., Raghuram, N. and Sivakami, S. (2004) Oxidative damage and altered antioxidant enzyme activities in the small intestine of streptozotocin in- duced diabetic rats. Int. J. Biochem. Cell Biol., 36, 89-97.
3. Baynes, J. W. (1991) Role of oxidative stress in de- velopment of complications in diabetes. Diabetes, 40,405-412.
4. Maritim, A. C., Sanders, R. A. and Watkins, J. B. (2003) Diabetes, oxidative stress, and antioxidants: a review. J. Biochem. Mol. Toxicol., 17, 24-38.
5. Mehta, J. L., Rasouli, N., Sinha, A. K. and Molavi, B. (2006) Oxidative stress in diabetes: A mechanis- tic overview of its effects on atherogenesis and my- ocardial dysfunction. Int. J. Biochem. Cell Biol., 38, 794-803.
6. Bartosikova, L., Necas, J., Suchy, V., Kubínova, R., Vesela, D., Benes, L., Illek, J., Salplachta, J., Florian, T., Frydrych, M., Klusakova, J., Bartosik, T., Frana, L., Frana, P. and Dzurova, J. (2003) An- tioxidative effect of morine in ischemia-reperfusion of kidneys in the laboratory rat. Acta Vet. Brno., 72, 87-94.
7. Blaha, L., Kopp, R., Simková, K. and Mares, J. (2004) Oxidative stress biomarkers are modulated in silver carp (Hypophthalmichthys molitrix Val.) ex- posed to microcystin-producing cyanobacterial water bloom. Acta Vet. Brno., 73, 477-482.
8. Dias, A. S., Porawski, M., Alonso, M., Marroni, N., Collado, P. S. and Gonzalez-Gallego, J. (2005) Quercetin decreases oxidative stress, NF-B activation, and iNOS overexpression in liver of streptozo- tocininduced diabetic rats. J. Nutr., 135, 2299-2304.
9. Mallikharjuna, P. B., Rajanna, L. N., Seetharam, Y. N. and Sharnabasappa, G. K. (2007) Phytochemi- cal studies of Stychnos potatorum L.-A Medicinal plant. E-Journal of Chemistry, 4, 510-518.
10. Sudhakar Nayak, S. and Pattabiraman, T. N. (1981) A new colorimetric method for the estimation of glycosylated hemoglobin. Clin. Chem. Acta, 109, 267-274.
11. Begum, N. and Shanmugasundaram, K. R. (1978) Transaminases in experimental diabetes. J. Health Sci., 4, 116-122.
12. Das, S., Vasight, S., Snehlata, R., Das, N. and Srivastava, L. M. (2000) Correlation between total antoxidant status and lipid peroxidation in hyperc- holesterolemia. Curr. Sci., 78, 486-487.
13. Sinha, A. K. (1972) Colorimetric assay of catalase. Anal. Biochem., 47, 389-394.
14. Beutler, E., Vulliamy, T. and Luzzatto, L. (1996) Hematologically important mutations glucose-6- phosphate dehydrogenase. Blood Cells Mol. Dis., 22,49-56.
15. Moron, M. S., Defierre, J. W. and Mannervik, B. (1979) Levels of glutathione, glutathione reductase and glutathione-s-transferase activities in rat lung and liver. J. Biochim. Biophys. Acta, 582, 67-68.
16. Sedlack, J. and Lindsay, R. H. (1968) Estimation of total protein bound and non-protein boundsul- phydryl groups in the tissue with Ellman's reagent. Anal. Biochem., 25, 192-205.
17. Uchiyama, M. and Mihara, M. (1978) Determination of malonaldehyde precursor in tissues by thio- barbituric acid test. Anal. Biochem., 86, 271-278.
18. Neeld, P., Burtis, C. A. and Ashwood, A. (1963) Text Book Of Clinical Chemistry, Vol.27, Saunders Company, Philadelphia, pp. 1280-1282.
19. Rosemberg, H. R. (1992) Chemistry and Physiology of the Vitamins, Interscience Publishers, New York, pp. 452-453.
20. Chatterjee, M. N. and Shinde, R. (2000) Metabolism of Carbohydrates. In Textbook of Medical Biochemistry, JayPee Medical Publishers, Delhi, p. 421.
21. Murray, R. K., Granner, D. K., Mayes, P. A. and Rodwell, V. W. (2000) Harper's Biochemistry, 25th Ed., Appleton and Lange, Stanford, pp. 610-617.
22. Grover, J. K., Vats, V. and Rathi, S. S. (2000) Antihyperglycemic effect of Eugenia jambolana and Tinosporacordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J. Ethnopharmacol., 73, 461-470.
23. Berg, J. M., Tymoczko, J. L. and Stryer, L. (2001) Glycolysis and gluconeogenesis. In Biochemistry (Berg, J. M., Tymoczko, J. L. and Stryer, L., (Eds.), WH Freeman and Company, New York, pp. 425- 464.
24. Guignot, L. and Mithieux, G. (1999) Mechanisms by which insulin, associated or not with glucose, may inhibit hepatic glucose production in the rate. Am. J. Physiol., 277, E984-E989.
25. Baquer, N. Z., Gupta, D. and Raju, J. (1988) Reg- ulations of metabolic pathways in liver and kidney during experimental diabetes. Effect of antidiabetic compounds. Indian J. Clin. Biochem., 13, 63-80.
26. Jorda, A., Gomez, M., Cabo, J. and Grisolia, S. (1982) Effect of streptozotocin diabetes on some urea cycle enzymes. Biochem. Biophys. Res. Com- mun., 106, 37-43.
27. Mohan Rao, G. M., Morghom, L. O., Kabar, M. N., Benmohamud, B. M. and Ashibani, K. (1989) Serum glutamic oxaloacetic transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in diabetes mellitus. Indian J. Med. Sci., 5, 118-122.
28. Prince, P. S. M., Menon, V. P. and Pari, L. (1997) Effect of Syzigium cumini extracts on hepatic hex- okinase and glucose 6-phosphatase in experimental diabetes. Phytother. Res., 11, 529-531.
29. Vagga, A. A., Deshpande, K. H., Katkam, R. V. and Suryakar, A. N. (2004) Oxidative stress and an- tioxidants status in diabetic retinopathy. Indian Med. Gaz., 9, 370-374.
30. Satheesh, M. A. and Pari, L. (2004) Antioxidant effect of Boerhavia diffuse L in tissues of alloxan in- duced diabetic rats. Indian J. Exp. Biol., 42, 989- 992.
31. Wolff, S. and Dean, R. T. (1987) Glucose autoox- idation and protein modification. Biochem. J., 245, 243-250.
32. Dass Vasisht, S., Snehlata, R., Das, N. and Srivastava, L. (2000) Correlations between total an- tioxidant status and lipid peroixation in hypercholes- terolemia. Curr. Sci., 78, 486.
33. Lu, S. C. (1999) Regulation of hepatic glutathione synthesis, current concepts and controversies. FASEB J., 13, 1169-1183.
34. Garg, M. C., Ojha, S. and Bansal, D. D. (1996) Antioxidant status of streptozotocin diabetic rats. In- dian J. Exp. Biol., 34, 264-266.
35. Bryszewska, M., Zavodnik, I. B., Niekurzak, A. and Szosland, K. (1995) Oxidative processes in red blood cells from normal and diabetic individuals. Biochem. Mol. Biol. Int., 37, 345-354.
36. Krishnakumar, K., Augusti, K. T. and Vijayammal, P. L. (1999) Hypoglycemic and antioxidant activity of Salacia oblonga Wall, Extract in streptozotocin induced diabetic rats. Indian J. Physiol. Pharmacol., 43,510-514.
37. Smith, T. A. (1998) Carotenoids and cancer: Prevention and potential therapy. Br. J. Biomed. Sci., 55, 268-275.
38. Kumar, G., Sharmila Banu, G., Kannan, V. and Rajasekarapandian, M. (2005) Antihepatotoxic ef- fect of pcarotene on paracetamol induced hepatic damage in rats. Indian J. Exp. Biol., 43, 351-355.
39. Jill Startman, F. W. and Lardy, H. A. (1988) Enzymatic down regulation with exercise in rat skeletal muscle. Biochem. Biophys., 263, 137-149.
40. Anuradha, C. V. and Balakrishnan, S. D. (1998) Effect of training on lipid peroxidation, thiol status and antioxidant enzymes in tissues of rats. Indian J. Physiol. Pharmacol., 42, 64-70.
41. Selloum, L., Reichl, S., Müller, M., Sebihi, L. and Arnhold, J. (2001) Effects of flavonols on the generation of superoxide anion radicals by xanthine oxidase and stimulated neutrophils. Arch. Biochem. Biophys., 395, 49-56.
42. Hanasaki, Y., Ogawa, S. and Fukui, S. (1994) The correlation between active oxygen scavenging and antioxidative effects of flavonoids. Free Radic. Biol. Med., 16, 845-850.
43. Manach, C., Morand, C., Crespy, V., Demigné, C., Texier, O. and Régérat, F. (2002) Flavonoid quercetin in chronic nitric oxide deficient rats. J. Hypertens., 20, 1843-1854.